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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited versus non-edited samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for MRPS30

check button Gene summary
Gene informationGene symbol

MRPS30

Gene ID

10884

Gene namemitochondrial ribosomal protein S30
SynonymsMRP-S30|PAP|PDCD9|S30mt
Cytomap

5p12

Type of geneprotein-coding
Description39S ribosomal protein S30, mitochondrial28S ribosomal protein S30, mitochondrialmitochondrial large ribosomal subunit protein mL65mitochondrial large ribosomal subunit protein mS30programmed cell death 9
Modification date20200313
UniProtAcc

Q9NP92,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for MRPS30

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1203714(44815550, +), ADediting_1203715(44815551, +), ADediting_1203716(44815566, +), ADediting_1203717(44815567, +), ADediting_1203718(44815573, +), ADediting_1203719(44815575, +), ADediting_1203720(44815588, +), ADediting_1203721(44815589, +), ADediting_1203722(44815607, +), ADediting_1203723(44815612, +), ADediting_1203724(44815615, +), ADediting_1203725(44815623, +), ADediting_1203726(44815626, +), ADediting_1203727(44815636, +), ADediting_1203728(44815644, +), ADediting_1203729(44815646, +), ADediting_1203730(44815651, +), ADediting_1203731(44815662, +), ADediting_1203732(44815663, +), ADediting_1203733(44815666, +), ADediting_1203734(44815668, +), ADediting_1203735(44815669, +), ADediting_1203736(44815670, +), ADediting_1203737(44815671, +), ADediting_1203738(44815672, +), ADediting_1203739(44815675, +), ADediting_1203740(44815702, +), ADediting_1203741(44815707, +), ADediting_1203742(44815711, +), ADediting_1203743(44815724, +), ADediting_1203744(44815731, +), ADediting_1203745(44815734, +), ADediting_1203746(44815737, +), ADediting_1203747(44815742, +), ADediting_1203748(44815743, +), ADediting_1203749(44815754, +), ADediting_1203750(44815767, +), ADediting_1203751(44815768, +), ADediting_1203752(44815772, +), ADediting_1203753(44815792, +), ADediting_1203754(44816252, +), ADediting_1203755(44816260, +), ADediting_1203756(44816278, +), ADediting_1203757(44816281, +), ADediting_1203758(44816290, +), ADediting_1203759(44816303, +), ADediting_1203760(44816304, +), ADediting_1203761(44816321, +), ADediting_1203762(44816330, +), ADediting_1203763(44816347, +), ADediting_1203764(44816349, +), ADediting_1203765(44816353, +), ADediting_1203766(44816373, +), ADediting_1203767(44816374, +), ADediting_1203768(44816383, +), ADediting_1203769(44816387, +), ADediting_1203770(44816407, +), ADediting_1203771(44816416, +), ADediting_1203772(44816441, +), ADediting_1203773(44816450, +), ADediting_1203774(44816467, +), ADediting_1203775(44816468, +), ADediting_1203776(44816469, +), ADediting_1203777(44816481, +), ADediting_1203778(44816483, +), ADediting_1203779(44816490, +), ADediting_1203780(44819764, +), ADediting_1203781(44819781, +), ADediting_1203782(44819786, +), ADediting_1203783(44819793, +), ADediting_1203784(44819807, +), ADediting_1203785(44819810, +), ADediting_1203786(44819856, +), ADediting_1203787(44819883, +), ADediting_1203788(44819890, +), ADediting_1203789(44819902, +), ADediting_1203790(44819927, +), ADediting_1203791(44819928, +), ADediting_1203792(44819954, +), ADediting_1581588(44815583, +), ADediting_1581589(44815621, +), ADediting_1581590(44815638, +), ADediting_1581591(44815643, +), ADediting_1581592(44815645, +), ADediting_1581593(44815657, +), ADediting_1581594(44815664, +), ADediting_1581595(44815701, +), ADediting_1581596(44819824, +), ADediting_1656963(44815730, +), ADediting_1656964(44816273, +), ADediting_1656965(44816308, +),

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RNA editing positional annotations for MRPS30 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1203714chr5_44815550_+downstream
ADediting_1203715chr5_44815551_+downstream
ADediting_1203716chr5_44815566_+downstream
ADediting_1203717chr5_44815567_+downstream
ADediting_1203718chr5_44815573_+downstream
ADediting_1203719chr5_44815575_+downstream
ADediting_1203720chr5_44815588_+downstream
ADediting_1203721chr5_44815589_+downstream
ADediting_1203722chr5_44815607_+downstream
ADediting_1203723chr5_44815612_+downstream
ADediting_1203724chr5_44815615_+downstream
ADediting_1203725chr5_44815623_+downstream
ADediting_1203726chr5_44815626_+downstream
ADediting_1203727chr5_44815636_+downstream
ADediting_1203728chr5_44815644_+downstream
ADediting_1203729chr5_44815646_+downstream
ADediting_1203730chr5_44815651_+downstream
ADediting_1203731chr5_44815662_+downstream
ADediting_1203732chr5_44815663_+downstream
ADediting_1203733chr5_44815666_+downstream
ADediting_1203734chr5_44815668_+downstream
ADediting_1203735chr5_44815669_+downstream
ADediting_1203736chr5_44815670_+downstream
ADediting_1203737chr5_44815671_+downstream
ADediting_1203738chr5_44815672_+downstream
ADediting_1203739chr5_44815675_+downstream
ADediting_1203740chr5_44815702_+downstream
ADediting_1203741chr5_44815707_+downstream
ADediting_1203742chr5_44815711_+downstream
ADediting_1203743chr5_44815724_+downstream
ADediting_1203744chr5_44815731_+downstream
ADediting_1203745chr5_44815734_+downstream
ADediting_1203746chr5_44815737_+downstream
ADediting_1203747chr5_44815742_+downstream
ADediting_1203748chr5_44815743_+downstream
ADediting_1203749chr5_44815754_+downstream
ADediting_1203750chr5_44815767_+downstream
ADediting_1203751chr5_44815768_+downstream
ADediting_1203752chr5_44815772_+downstream
ADediting_1203753chr5_44815792_+downstream
ADediting_1203754chr5_44816252_+downstream
ADediting_1203755chr5_44816260_+downstream
ADediting_1203756chr5_44816278_+downstream
ADediting_1203757chr5_44816281_+downstream
ADediting_1203758chr5_44816290_+downstream
ADediting_1203759chr5_44816303_+downstream
ADediting_1203760chr5_44816304_+downstream
ADediting_1203761chr5_44816321_+downstream
ADediting_1203762chr5_44816330_+downstream
ADediting_1203763chr5_44816347_+downstream
ADediting_1203764chr5_44816349_+downstream
ADediting_1203765chr5_44816353_+downstream
ADediting_1203766chr5_44816373_+downstream
ADediting_1203767chr5_44816374_+downstream
ADediting_1203768chr5_44816383_+downstream
ADediting_1203769chr5_44816387_+downstream
ADediting_1203770chr5_44816407_+downstream
ADediting_1203771chr5_44816416_+downstream
ADediting_1203772chr5_44816441_+downstream
ADediting_1203773chr5_44816450_+downstream
ADediting_1203774chr5_44816467_+downstream
ADediting_1203775chr5_44816468_+downstream
ADediting_1203776chr5_44816469_+downstream
ADediting_1203777chr5_44816481_+downstream
ADediting_1203778chr5_44816483_+downstream
ADediting_1203779chr5_44816490_+downstream
ADediting_1203780chr5_44819764_+intergenic
ADediting_1203781chr5_44819781_+intergenic
ADediting_1203782chr5_44819786_+intergenic
ADediting_1203783chr5_44819793_+intergenic
ADediting_1203784chr5_44819807_+intergenic
ADediting_1203785chr5_44819810_+intergenic
ADediting_1203786chr5_44819856_+intergenic
ADediting_1203787chr5_44819883_+intergenic
ADediting_1203788chr5_44819890_+intergenic
ADediting_1203789chr5_44819902_+intergenic
ADediting_1203790chr5_44819927_+intergenic
ADediting_1203791chr5_44819928_+intergenic
ADediting_1203792chr5_44819954_+intergenic
ADediting_1581588chr5_44815583_+downstream
ADediting_1581589chr5_44815621_+downstream
ADediting_1581590chr5_44815638_+downstream
ADediting_1581591chr5_44815643_+downstream
ADediting_1581592chr5_44815645_+downstream
ADediting_1581593chr5_44815657_+downstream
ADediting_1581594chr5_44815664_+downstream
ADediting_1581595chr5_44815701_+downstream
ADediting_1581596chr5_44819824_+intergenic
ADediting_1656963chr5_44815730_+downstream
ADediting_1656964chr5_44816273_+downstream
ADediting_1656965chr5_44816308_+downstream

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1203714chr5_44815550_+SINEAluName=AluSz6
ADediting_1203715chr5_44815551_+SINEAluName=AluSz6
ADediting_1203716chr5_44815566_+SINEAluName=AluSz6
ADediting_1203717chr5_44815567_+SINEAluName=AluSz6
ADediting_1203718chr5_44815573_+SINEAluName=AluSz6
ADediting_1203719chr5_44815575_+SINEAluName=AluSz6
ADediting_1203720chr5_44815588_+SINEAluName=AluSz6
ADediting_1203721chr5_44815589_+SINEAluName=AluSz6
ADediting_1203722chr5_44815607_+SINEAluName=AluSz6
ADediting_1203723chr5_44815612_+SINEAluName=AluSz6
ADediting_1203724chr5_44815615_+SINEAluName=AluSz6
ADediting_1203725chr5_44815623_+SINEAluName=AluSz6
ADediting_1203726chr5_44815626_+SINEAluName=AluSz6
ADediting_1203727chr5_44815636_+SINEAluName=AluSz6
ADediting_1203728chr5_44815644_+SINEAluName=AluSz6
ADediting_1203729chr5_44815646_+SINEAluName=AluSz6
ADediting_1203730chr5_44815651_+SINEAluName=AluSz6
ADediting_1203731chr5_44815662_+SINEAluName=AluSz6
ADediting_1203732chr5_44815663_+SINEAluName=AluSz6
ADediting_1203733chr5_44815666_+SINEAluName=AluSz6
ADediting_1203734chr5_44815668_+SINEAluName=AluSz6
ADediting_1203735chr5_44815669_+SINEAluName=AluSz6
ADediting_1203736chr5_44815670_+SINEAluName=AluSz6
ADediting_1203737chr5_44815671_+SINEAluName=AluSz6
ADediting_1203738chr5_44815672_+SINEAluName=AluSz6
ADediting_1203739chr5_44815675_+SINEAluName=AluSz6
ADediting_1203740chr5_44815702_+SINEAluName=AluSz6
ADediting_1203741chr5_44815707_+SINEAluName=AluSz6
ADediting_1203742chr5_44815711_+SINEAluName=AluSz6
ADediting_1203743chr5_44815724_+SINEAluName=AluSz6
ADediting_1203744chr5_44815731_+SINEAluName=AluSz6
ADediting_1203745chr5_44815734_+SINEAluName=AluSz6
ADediting_1203746chr5_44815737_+SINEAluName=AluSz6
ADediting_1203747chr5_44815742_+SINEAluName=AluSz6
ADediting_1203748chr5_44815743_+SINEAluName=AluSz6
ADediting_1203749chr5_44815754_+SINEAluName=AluSz6
ADediting_1203750chr5_44815767_+SINEAluName=AluSz6
ADediting_1203751chr5_44815768_+SINEAluName=AluSz6
ADediting_1203752chr5_44815772_+SINEAluName=AluSz6
ADediting_1203753chr5_44815792_+SINEAluName=AluSz6
ADediting_1203754chr5_44816252_+SINEAluName=AluSp
ADediting_1203755chr5_44816260_+SINEAluName=AluSp
ADediting_1203756chr5_44816278_+SINEAluName=AluSp
ADediting_1203757chr5_44816281_+SINEAluName=AluSp
ADediting_1203758chr5_44816290_+SINEAluName=AluSp
ADediting_1203759chr5_44816303_+SINEAluName=AluSp
ADediting_1203760chr5_44816304_+SINEAluName=AluSp
ADediting_1203761chr5_44816321_+SINEAluName=AluSp
ADediting_1203762chr5_44816330_+SINEAluName=AluSp
ADediting_1203763chr5_44816347_+SINEAluName=AluSp
ADediting_1203764chr5_44816349_+SINEAluName=AluSp
ADediting_1203765chr5_44816353_+SINEAluName=AluSp
ADediting_1203766chr5_44816373_+SINEAluName=AluSp
ADediting_1203767chr5_44816374_+SINEAluName=AluSp
ADediting_1203768chr5_44816383_+SINEAluName=AluSp
ADediting_1203769chr5_44816387_+SINEAluName=AluSp
ADediting_1203770chr5_44816407_+SINEAluName=AluSp
ADediting_1203771chr5_44816416_+SINEAluName=AluSp
ADediting_1203772chr5_44816441_+SINEAluName=AluSp
ADediting_1203773chr5_44816450_+SINEAluName=AluSp
ADediting_1203774chr5_44816467_+SINEAluName=AluSp
ADediting_1203775chr5_44816468_+SINEAluName=AluSp
ADediting_1203776chr5_44816469_+SINEAluName=AluSp
ADediting_1203777chr5_44816481_+SINEAluName=AluSp
ADediting_1203778chr5_44816483_+SINEAluName=AluSp
ADediting_1203779chr5_44816490_+SINEAluName=AluSp
ADediting_1203780chr5_44819764_+SINEAluName=AluSz
ADediting_1203781chr5_44819781_+SINEAluName=AluSz
ADediting_1203782chr5_44819786_+SINEAluName=AluSz
ADediting_1203783chr5_44819793_+SINEAluName=AluSz
ADediting_1203784chr5_44819807_+SINEAluName=AluSz
ADediting_1203785chr5_44819810_+SINEAluName=AluSz
ADediting_1203786chr5_44819856_+SINEAluName=AluSz
ADediting_1203787chr5_44819883_+SINEAluName=AluSz
ADediting_1203788chr5_44819890_+SINEAluName=AluSz
ADediting_1203789chr5_44819902_+SINEAluName=AluSz
ADediting_1203790chr5_44819927_+SINEAluName=AluSz
ADediting_1203791chr5_44819928_+SINEAluName=AluSz
ADediting_1203792chr5_44819954_+SINEAluName=AluSz
ADediting_1581588chr5_44815583_+SINEAluName=AluSz6
ADediting_1581589chr5_44815621_+SINEAluName=AluSz6
ADediting_1581590chr5_44815638_+SINEAluName=AluSz6
ADediting_1581591chr5_44815643_+SINEAluName=AluSz6
ADediting_1581592chr5_44815645_+SINEAluName=AluSz6
ADediting_1581593chr5_44815657_+SINEAluName=AluSz6
ADediting_1581594chr5_44815664_+SINEAluName=AluSz6
ADediting_1581595chr5_44815701_+SINEAluName=AluSz6
ADediting_1581596chr5_44819824_+SINEAluName=AluSz
ADediting_1656963chr5_44815730_+SINEAluName=AluSz6
ADediting_1656964chr5_44816273_+SINEAluName=AluSp
ADediting_1656965chr5_44816308_+SINEAluName=AluSp

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RNA A-to-I editing events in the alternative splicing sites for MRPS30

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MRPS30

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for MRPS30

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for MRPS30

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1203715chr5_44815551_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3130-3pchr544815545448155517mer-m84481552944815552149-22.69
ADediting_1203715chr5_44815551_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-324-3pchr544815548448155547mer-m84481553244815555170-34.39
ADediting_1203715chr5_44815551_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-4252chr544815549448155557mer-m84481553744815556154-22.79
ADediting_1203773chr5_44816450_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-1228-5pchr544816448448164547mer-m84481555544816455162-33.11
ADediting_1203774chr5_44816467_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-6771-5pchr544816462448164698mer-1a4481644844816469151-24.79
ADediting_1203775chr5_44816468_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-326chr544816464448164707mer-m84481645244816471140-13.37
ADediting_1203775chr5_44816468_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-330-5pchr544816464448164707mer-m84481645044816471140-20.32
ADediting_1203775chr5_44816468_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-4314chr544816463448164697mer-m84481645344816470140-21.18
ADediting_1203775chr5_44816468_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-514a-5pchr544816465448164717mer-m84481644944816472146-18.62
ADediting_1203776chr5_44816469_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3189-3pchr544816464448164707mer-m84481644844816471153-24.71
ADediting_1203776chr5_44816469_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-6813-3pchr544816465448164717mer-m84481645244816472140-11.6
ADediting_1203778chr5_44816483_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-100-5pchr544816480448164867mer-m84481646544816487162-22.89
ADediting_1203778chr5_44816483_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-99a-5pchr544816480448164867mer-m84481646444816487155-21.46
ADediting_1203778chr5_44816483_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-99b-5pchr544816480448164867mer-m84481646444816487155-25.13
ADediting_1203779chr5_44816490_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-663bchr544816489448164957mer-m84481647544816496147-24.56
ADediting_1203780chr5_44819764_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-383-3pchr544819761448197677mer-m84481974744819768156-24.23
ADediting_1203782chr5_44819786_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-6089chr544819785448197917mer-m84481976944819792169-38.13
ADediting_1203783chr5_44819793_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-25-5pchr544819789448197957mer-m84481977244819796149-24
ADediting_1203783chr5_44819793_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-658chr544819788448197947mer-m84481976944819795153-28.47
ADediting_1203784chr5_44819807_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3140-5pchr544819802448198087mer-m84481979144819809156-14.54
ADediting_1203784chr5_44819807_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-5187-3pchr544819801448198077mer-m84481978844819808145-11.7
ADediting_1203786chr5_44819856_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-4442chr544819851448198577mer-m84481984244819858146-21.92
ADediting_1203787chr5_44819883_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-548as-3pchr544819882448198887mer-m84481986744819889146-9.47
ADediting_1203787chr5_44819883_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-660-5pchr544819879448198857mer-m84481986544819886141-10.24
ADediting_1203789chr5_44819902_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3940-3pchr544819900448199067mer-m84481988944819907144-24.53
ADediting_1203791chr5_44819928_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3622a-3pchr544819925448199328mer-1a4481991144819932144-13.55
ADediting_1203791chr5_44819928_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3622b-3pchr544819925448199328mer-1a4481991244819932153-19.33
ADediting_1203791chr5_44819928_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-544bchr544819923448199297mer-m84481991044819930157-19.04
ADediting_1203791chr5_44819928_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-7162-3pchr544819922448199287mer-m84481990944819929142-17.47
ADediting_1203792chr5_44819954_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3189-3pchr544819949448199557mer-m84481993344819956144-22.22
ADediting_1581596chr5_44819824_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-6089chr544819823448198297mer-m84481980744819830164-37.06

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1203714chr5_44815550_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-32-5pchr544815546448155527mer-m84481553144815553147-18.09
ADediting_1203714chr5_44815550_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-363-3pchr544815546448155527mer-m84481553744815553142-16.75
ADediting_1203714chr5_44815550_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-367-3pchr544815546448155527mer-m84481553044815553154-17.15
ADediting_1203714chr5_44815550_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-500a-3pchr544815545448155517mer-1a4481552744815551142-20.8
ADediting_1203714chr5_44815550_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-92a-3pchr544815546448155527mer-m84481553244815553145-18.9
ADediting_1203714chr5_44815550_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-92b-3pchr544815546448155527mer-m84481553244815553149-18.7
ADediting_1203715chr5_44815551_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-32-5pchr544815546448155527mer-m84481553144815553147-18.09
ADediting_1203715chr5_44815551_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-363-3pchr544815546448155527mer-m84481553744815553142-16.75
ADediting_1203715chr5_44815551_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-367-3pchr544815546448155527mer-m84481553044815553154-17.15
ADediting_1203715chr5_44815551_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-92a-3pchr544815546448155527mer-m84481553244815553145-18.9
ADediting_1203715chr5_44815551_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-92b-3pchr544815546448155527mer-m84481553244815553149-18.7
ADediting_1203773chr5_44816450_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3165chr544816446448164527mer-m84481555144816453150-17.86
ADediting_1203773chr5_44816450_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-6745chr544816447448164548mer-1a4481555444816454154-22.8
ADediting_1203773chr5_44816450_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-6748-5pchr544816449448164557mer-m84481555344816456149-23.57
ADediting_1203774chr5_44816467_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-30b-3pchr544816461448164688mer-1a4481644744816468155-18.05
ADediting_1203774chr5_44816467_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3689a-3pchr544816461448164688mer-1a4481644744816468145-21.61
ADediting_1203774chr5_44816467_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3689b-3pchr544816461448164688mer-1a4481644744816468145-21.66
ADediting_1203774chr5_44816467_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3689cchr544816461448164688mer-1a4481644744816468145-21.66
ADediting_1203774chr5_44816467_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-6779-5pchr544816461448164688mer-1a4481644544816468151-24.22
ADediting_1203774chr5_44816467_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-6780a-5pchr544816461448164688mer-1a4481644544816468148-20.23
ADediting_1203774chr5_44816467_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-887-5pchr544816462448164698mer-1a4481644944816469147-13.82
ADediting_1203775chr5_44816468_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-887-5pchr544816462448164698mer-1a4481644944816469147-13.82
ADediting_1203779chr5_44816490_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-4284chr544816487448164948mer-1a4481647744816494151-19.56
ADediting_1203780chr5_44819764_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-101-3pchr544819762448197687mer-m84481975044819769151-16.57
ADediting_1203781chr5_44819781_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-6807-5pchr544819775448197817mer-m84481976144819782141-18.61
ADediting_1203782chr5_44819786_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-17-3pchr544819781448197877mer-m84481976844819788153-17.56
ADediting_1203782chr5_44819786_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-485-5pchr544819785448197917mer-m84481977244819792153-17.86
ADediting_1203782chr5_44819786_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-6884-5pchr544819785448197917mer-m84481977044819792146-20.16
ADediting_1203783chr5_44819793_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-12114chr544819790448197967mer-m84481977544819797155-25.76
ADediting_1203783chr5_44819793_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-4443chr544819787448197937mer-m84481977744819794143-17.78
ADediting_1203783chr5_44819793_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-7847-3pchr544819788448197947mer-m84481977344819795146-20.12
ADediting_1203786chr5_44819856_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-1207-3pchr544819854448198618mer-1a4481984444819861144-15.42
ADediting_1203786chr5_44819856_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-4638-3pchr544819851448198577mer-m84481983544819858145-22.83
ADediting_1203787chr5_44819883_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-5696chr544819877448198837mer-m84481986144819884145-12.5
ADediting_1203789chr5_44819902_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-3190-5pchr544819897448199037mer-m84481988544819904147-18.34
ADediting_1203789chr5_44819902_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-548schr544819896448199027mer-m84481987744819903147-12.43
ADediting_1581596chr5_44819824_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-4478chr544819822448198287mer-m84481981444819829149-25.05
ADediting_1581596chr5_44819824_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-4649-3pchr544819819448198257mer-m84481980644819826140-15.87
ADediting_1581596chr5_44819824_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-485-5pchr544819823448198297mer-m84481980944819830153-20.11
ADediting_1581596chr5_44819824_+ENSG00000112996.11ENST00000230914.4MRPS30-201hsa-miR-7160-5pchr544819820448198267mer-m84481980544819827149-20.61

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1535953chr14_101045971_+ENSG00000112996.11ENST00000507110.6MRPS30-202hsa-miR-381-3pchr544815413448154197mer-1a4481539844815419141-12.62
ADediting_1535954chr14_101045974_+ENSG00000112996.11ENST00000507110.6MRPS30-202hsa-miR-381-3pchr544815413448154197mer-1a4481539844815419141-12.62

check button Differentially expressed gene-miRNA network
Differentially expressed lncRNA-miRNA network
boxplot

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The effects of the RNA editing to the stability of the RNA structures for MRPS30

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000230914.4lncRNASoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1203714ENST00000230914.4chr5_44815550_+332-1071.40-1072.10-1103.10
ADediting_1203715ENST00000230914.4chr5_44815551_+333-1078.30-1072.10-1103.10
ADediting_1203773ENST00000230914.4chr5_44816450_+353-1072.30-1072.10-1103.10
ADediting_1203774ENST00000230914.4chr5_44816467_+370-1077.70-1072.10-1103.10
ADediting_1203775ENST00000230914.4chr5_44816468_+371-1074.00-1072.10-1103.10
ADediting_1203776ENST00000230914.4chr5_44816469_+372-1078.30-1072.10-1103.10
ADediting_1203777ENST00000230914.4chr5_44816481_+384-1071.10-1072.10-1103.10
ADediting_1203778ENST00000230914.4chr5_44816483_+386-1071.40-1072.10-1103.10
ADediting_1203779ENST00000230914.4chr5_44816490_+393-1071.20-1072.10-1103.10
ADediting_1203780ENST00000230914.4chr5_44819764_+3667-1074.70-1072.10-1103.10
ADediting_1203781ENST00000230914.4chr5_44819781_+3684-1072.10-1072.10-1103.10
ADediting_1203782ENST00000230914.4chr5_44819786_+3689-1072.10-1072.10-1103.10
ADediting_1203783ENST00000230914.4chr5_44819793_+3696-1071.70-1072.10-1103.10
ADediting_1203784ENST00000230914.4chr5_44819807_+3710-1076.00-1072.10-1103.10
ADediting_1203785ENST00000230914.4chr5_44819810_+3713-1073.00-1072.10-1103.10
ADediting_1581596ENST00000230914.4chr5_44819824_+3727-1074.10-1072.10-1103.10
ADediting_1203786ENST00000230914.4chr5_44819856_+3759-1072.00-1072.10-1103.10
ADediting_1203787ENST00000230914.4chr5_44819883_+3786-1072.10-1072.10-1103.10
ADediting_1203788ENST00000230914.4chr5_44819890_+3793-1072.80-1072.10-1103.10
ADediting_1203789ENST00000230914.4chr5_44819902_+3805-1072.10-1072.10-1103.10
ADediting_1203790ENST00000230914.4chr5_44819927_+3830-1071.80-1072.10-1103.10
ADediting_1203791ENST00000230914.4chr5_44819928_+3831-1072.10-1072.10-1103.10
ADediting_1203792ENST00000230914.4chr5_44819954_+3857-1073.90-1072.10-1103.10

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Relation with ADAR for MRPS30

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_1203715chr5_44815551_+4.36430264766592e-080.304785063686570.005291361156443490.1580316911394020.933681997396312-0.0047453369946994
CERADediting_1203715chr5_44815551_+2.68778721265528e-070.4052439316762741.50086601113463e-060.3810874968061399.74709938157278e-060.352406934911611
CERADediting_1203716chr5_44815566_+7.85262424341476e-050.3167310394780740.0005302643750990390.2795899048630610.001026592039335850.265461352932842
DLPFCADediting_1203718chr5_44815573_+1.03032175063344e-080.3180001731824255.38129760337631e-050.2272761822658630.2134528143842410.0708590682721059
CERADediting_1203718chr5_44815573_+1.65259335545829e-160.607641433843961.33876299863902e-160.6090985453428469.34562182262051e-060.353083062128062
TCXADediting_1203718chr5_44815573_+2.04066830587462e-050.3402684681467180.1249830989328780.1258202245351850.03436789352989190.172891741660286
CERADediting_1203720chr5_44815588_+8.77958205248575e-120.5203727265593461.83591446072336e-140.5729625736960530.001273598382489140.260681143137336
TCXADediting_1203720chr5_44815588_+2.09940603452594e-050.3397920938193277.765885767513e-060.356041287023940.0790995478697265-0.143828257505085
IFGADediting_1203723chr5_44815612_+0.7512073570601330.06675646710948520.765533918975240.0628006318378350.006962275131725830.525658428401746
STGADediting_1203725chr5_44815623_+0.48880251970544-0.07656305526066930.531408914697745-0.06924204904722640.002811538249167020.322069415251864
CERADediting_1203726chr5_44815626_+0.0001680080006412960.30253235346332.76832576434622e-080.4345016238170590.3489569878252070.077004792918949
CERADediting_1203730chr5_44815651_+1.10331611184145e-060.3855529808123031.45487578222099e-090.4687204192551590.00958045446063480.210902418129262
CERADediting_1203733chr5_44815666_+2.24093334463626e-110.5115255690432231.62508455875793e-130.5554072768100740.0086831718308690.213580169249167
CERADediting_1203735chr5_44815669_+2.13714749989437e-100.4891307319594718.61380515989328e-110.4983505501761170.00203671304440630.249955391784059
TCXADediting_1203735chr5_44815669_+2.24770024251047e-050.3386431068218820.3693577779568370.07381244915634334.08575428099978e-050.328383541293655
IFGADediting_1203735chr5_44815669_+0.5439485761809390.1273965996269640.3628865515897230.1900388647892580.007192714558102380.523866682964641
CERADediting_1203739chr5_44815675_+2.49755793043613e-120.5318542818967451.0959651477987e-150.5942075453873480.0005680107319895790.278153787304273
IFGADediting_1203739chr5_44815675_+0.6350419800920160.09980025568012030.6064149513231870.1082792044381960.002214493187112090.583198039162852
CERADediting_1203744chr5_44815731_+3.0586680024033e-070.4034934697400182.42606576215551e-100.4878220950917760.08158680785434820.142662322868869
TCXADediting_1203744chr5_44815731_+0.0008178477585661060.2704086399197321.9994946773299e-070.4092127609222290.0243429063266812-0.183816631603904
CERADediting_1203746chr5_44815737_+2.95555278572672e-080.4336969099291011.86717243887454e-100.4905184411299470.001376914969469410.258929892352601
TCXADediting_1203746chr5_44815737_+0.001442040041685560.257886681059232.8209619393703e-050.3347858018283250.348754813081452-0.0770370052182631
CERADediting_1203749chr5_44815754_+1.95445623698312e-090.4654565970595271.48082040142498e-120.536504071194130.04180113810877170.166428743466147
CERADediting_1203754chr5_44816252_+1.05424342029646e-160.6107426138279239.72635026519896e-150.5778875039290920.01445147959743850.199360903071551
TCXADediting_1203754chr5_44816252_+6.3286003856879e-050.3206322297263290.06185155487713490.1528506487454480.01269609289991110.203059917157081
CERADediting_1203757chr5_44816281_+0.0001128643609820280.3100485707275120.0002392180118827210.2956813106807480.489762657234670.056824075001442
CERADediting_1203758chr5_44816290_+5.3802807046651e-090.4539924387082321.0593740145425e-090.4721902449855380.3268786196954920.0805948967673082
CERADediting_1203760chr5_44816304_+0.0001319375840997270.3071225873968513.55455191124255e-050.3308074308845980.5822026732304080.0452769200191422
IFGADediting_1203760chr5_44816304_+0.06185104979658130.3788094891330230.008781357911580780.5126735904352880.5151978621863540.136531344773757
CERADediting_1203761chr5_44816321_+0.004074336529110950.2332339690700634.27729017669294e-050.3275817508025620.1035478916191910.133437953609536
CERADediting_1203771chr5_44816416_+9.6590908267616e-050.3129362564864784.68315177286027e-050.3259886017706780.598143198195290.0433779056816445
CERADediting_1203772chr5_44816441_+0.0001771047729089020.30152072394623.250188425654e-070.4026675456970930.007163456882964480.218732485188924
CERADediting_1203776chr5_44816469_+6.92216501640421e-050.3190178301016140.007416247812715750.2178119971348470.02515368073635670.182802314595663
CERADediting_1203777chr5_44816481_+4.53926017635565e-070.3980844109169852.35560762162404e-050.3378510927516690.004911961983535930.228524778399533
IFGADediting_1203777chr5_44816481_+0.717066832599078-0.07627563954672490.6666349100818970.09061575626433070.0222438157823650.455151098111274

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC4.44541822680015e-700.7992465479220734.19682033571263e-430.6781738253232490.7368438447868940.0191612070752401
AC2.28652357797971e-700.8481095124381865.94345318922987e-700.846830734627120.1154610968531520.0998071608007946
PCC4.72709078584552e-440.8013871598486161.37088796355796e-560.8580295459879080.4687654062807940.052731865199782
CER6.73522826390577e-500.8807518085299872.20002669295519e-260.7314222657674410.03608482841133320.171301191593687
TCX2.29651877803196e-460.8658643120503872.1258788145943e-260.7315686563525260.579489973795638-0.0456024511298398
FP2.87687085086237e-170.5782070857062026.96359365663077e-310.7298197001819480.660625117555252-0.0331325985910103
IFG1.91547678066105e-070.8363508319005646.63693920585468e-050.7116396817863990.9907812442461430.00243554665963808
PG8.51182942304865e-580.867854813133065.01298829042266e-390.7782184736250170.224570825836151-0.0894732251448549
STG6.4304817167143e-170.7585344722011171.21330961355712e-210.8208071095819080.262116183670344-0.123738309268964

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Relation with AD stages for MRPS30

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_1203718chr5_44815573_+1.90850280391525e-050.398830698502996
CERADediting_1203720chr5_44815588_+0.0013024460907310.305527643967331
CERADediting_1203730chr5_44815651_+0.0006040313226383090.324815830539614
CERADediting_1203733chr5_44815666_+1.9641167507108e-050.398283526866437
CERADediting_1203735chr5_44815669_+0.0003537685268834240.337533289746701
CERADediting_1203739chr5_44815675_+0.0001107250038612170.363413828245581
CERADediting_1203754chr5_44816252_+0.001301464433906510.305547214653783
TCXADediting_1203716chr5_44815566_+4.53310896895115e-050.385298332802612
TCXADediting_1203717chr5_44815567_+5.5171980223294e-050.381294454900631
TCXADediting_1203735chr5_44815669_+5.63586670738968e-050.380857619815848
TCXADediting_1203739chr5_44815675_+1.93624780713935e-060.443383817987602
TCXADediting_1203754chr5_44816252_+1.55013382610197e-050.406299147614194
TCXADediting_1203760chr5_44816304_+0.0002742087573594890.346499020497558

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER0.0008802415123305730.315522668945613

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RelatedDrugs for MRPS30

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MRPS30

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource