ADeditome: functional annotation of RNA A-to-I editing in AD

Gene summary for ZNF273

Gene summary

Gene information	Gene symbol	ZNF273
	Gene ID	10793
	Gene name	zinc finger protein 273
	Synonyms	HZF9
	Cytomap	7q11.21
	Type of gene	protein-coding
	Description	zinc finger protein 273zinc finger protein 9zinc finger protein HZF9
	Modification date	20200313
	UniProtAcc	Q14593,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for ZNF273

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_1344211(64894134, +), ADediting_1344212(64894185, +), ADediting_1344213(64894191, +), ADediting_1344214(64894194, +), ADediting_1344215(64894214, +), ADediting_1344216(64894234, +), ADediting_1344217(64894279, +), ADediting_1344218(64894874, +), ADediting_1344219(64894880, +), ADediting_1344220(64894932, +), ADediting_1344221(64894946, +), ADediting_1344222(64894951, +), ADediting_1344223(64894952, +), ADediting_1344224(64895016, +), ADediting_1344225(64895017, +), ADediting_1344226(64895062, +), ADediting_1344227(64897353, +), ADediting_1344228(64897396, +), ADediting_1344229(64897420, +), ADediting_1344230(64897456, +), ADediting_1344231(64897488, +), ADediting_1344232(64897492, +), ADediting_1344233(64897493, +), ADediting_1344234(64897502, +), ADediting_1344235(64897508, +), ADediting_1344236(64897511, +), ADediting_1344237(64897565, +), ADediting_1344238(64897588, +), ADediting_1344239(64897600, +), ADediting_1344240(64897844, +), ADediting_1344241(64897856, +), ADediting_1344242(64897866, +), ADediting_1344243(64897892, +), ADediting_1344244(64897909, +), ADediting_1344245(64897912, +), ADediting_1344246(64897918, +), ADediting_1344247(64897926, +), ADediting_1344248(64897934, +), ADediting_1344249(64897938, +), ADediting_1344250(64897989, +), ADediting_1344251(64898001, +), ADediting_1344252(64899383, +), ADediting_1344253(64899400, +), ADediting_1344254(64899427, +), ADediting_1344255(64899445, +), ADediting_1344256(64899469, +), ADediting_1344257(64899471, +), ADediting_1344258(64899479, +), ADediting_1344259(64899484, +), ADediting_1344260(64899490, +), ADediting_1344261(64899493, +), ADediting_1344262(64899494, +), ADediting_1344263(64899499, +), ADediting_1344264(64899508, +), ADediting_1344265(64899512, +), ADediting_1344266(64899528, +), ADediting_1344267(64899534, +), ADediting_1344268(64899535, +), ADediting_1344269(64899551, +), ADediting_1344270(64899557, +), ADediting_1344271(64899561, +), ADediting_1344272(64899562, +), ADediting_1344273(64899567, +), ADediting_1344274(64899570, +), ADediting_1344275(64899588, +), ADediting_1344276(64899601, +), ADediting_1344277(64899605, +), ADediting_1344278(64899606, +), ADediting_1344279(64899817, +), ADediting_1344280(64899860, +), ADediting_1344281(64899861, +), ADediting_1344282(64899887, +), ADediting_1344283(64899890, +), ADediting_1344284(64899900, +), ADediting_1344285(64899906, +), ADediting_1344286(64899927, +), ADediting_1344287(64899934, +), ADediting_1344288(64899940, +), ADediting_1344289(64899969, +), ADediting_1344290(64899988, +), ADediting_1344291(64900239, +), ADediting_1344292(64900306, +), ADediting_1344293(64900309, +), ADediting_1344294(64900360, +), ADediting_1344295(64900361, +), ADediting_1344296(64901103, +), ADediting_1344297(64901113, +), ADediting_1344298(64901115, +), ADediting_1344299(64901120, +), ADediting_1344300(64901142, +), ADediting_1344301(64901145, +), ADediting_1344302(64901158, +), ADediting_1344303(64901160, +), ADediting_1344304(64901168, +), ADediting_1344305(64901169, +), ADediting_1344306(64901183, +), ADediting_1344307(64901225, +), ADediting_1344308(64901695, +), ADediting_1344309(64901696, +), ADediting_1344310(64901701, +), ADediting_1344311(64901786, +), ADediting_1344312(64901803, +), ADediting_1344313(64901829, +), ADediting_1344314(64901830, +), ADediting_1344315(64901839, +), ADediting_1344316(64901859, +), ADediting_1344317(64901862, +), ADediting_1344318(64902452, +), ADediting_1344319(64902510, +), ADediting_1344320(64902515, +), ADediting_1344321(64902520, +), ADediting_1344322(64902528, +), ADediting_1344323(64902529, +), ADediting_1344324(64902544, +), ADediting_1344325(64902554, +), ADediting_1344326(64902574, +), ADediting_1344327(64902583, +), ADediting_1344328(64902591, +), ADediting_1344329(64902604, +), ADediting_1344330(64902608, +), ADediting_1344331(64902641, +), ADediting_1344332(64902650, +), ADediting_1344333(64904119, +), ADediting_1344334(64904144, +), ADediting_1344335(64904163, +), ADediting_1344336(64904192, +), ADediting_1344337(64904193, +), ADediting_1344338(64904270, +), ADediting_1344339(64904273, +), ADediting_1344340(64904324, +), ADediting_1344341(64904358, +), ADediting_1344342(64905215, +), ADediting_1344343(64905216, +), ADediting_1344344(64905233, +), ADediting_1344345(64905299, +), ADediting_1344346(64905351, +), ADediting_1344347(64905363, +), ADediting_1344351(64915941, +), ADediting_1344352(64915971, +), ADediting_1344353(64915972, +), ADediting_1344354(64915994, +), ADediting_1344355(64915995, +), ADediting_1344356(64916040, +), ADediting_1344357(64916049, +), ADediting_1344358(64916085, +), ADediting_1344359(64916088, +), ADediting_1344360(64916102, +), ADediting_1344361(64916128, +), ADediting_1344362(64916457, +), ADediting_1344363(64918452, +), ADediting_1344364(64918505, +), ADediting_1344365(64918514, +), ADediting_1344366(64918540, +), ADediting_1344367(64919369, +), ADediting_1344368(64919548, +), ADediting_1344369(64921121, +), ADediting_1344370(64921164, +), ADediting_1344371(64921165, +), ADediting_1344372(64921169, +), ADediting_1344373(64921286, +), ADediting_1344374(64921679, +), ADediting_1344375(64921726, +), ADediting_1344376(64922393, +), ADediting_1344377(64922409, +), ADediting_1344378(64922429, +), ADediting_1344379(64922492, +), ADediting_1344380(64922547, +), ADediting_1344381(64922564, +), ADediting_1344382(64922586, +), ADediting_1344383(64922740, +), ADediting_1344384(64922769, +), ADediting_1344385(64922779, +), ADediting_1344386(64922789, +), ADediting_1344387(64922803, +), ADediting_1344388(64922809, +), ADediting_1344389(64922823, +), ADediting_1344390(64922886, +), ADediting_1344391(64922891, +), ADediting_1344392(64922915, +), ADediting_1344393(64922916, +), ADediting_1344394(64922941, +), ADediting_1344395(64923421, +), ADediting_1344396(64923441, +), ADediting_1344397(64923442, +), ADediting_1344398(64923525, +), ADediting_1344399(64923571, +), ADediting_1344400(64927149, +), ADediting_1344401(64927162, +), ADediting_1344402(64927193, +), ADediting_1344403(64927222, +), ADediting_1344404(64929936, +), ADediting_1344405(64930006, +), ADediting_1344406(64930047, +), ADediting_1344407(64930053, +), ADediting_1587993(64897540, +), ADediting_1587994(64899422, +), ADediting_1587995(64899435, +), ADediting_1587996(64899497, +), ADediting_1587997(64899505, +), ADediting_1587998(64899585, +), ADediting_1587999(64900264, +), ADediting_1588000(64900292, +), ADediting_1588001(64900335, +), ADediting_1588002(64901039, +), ADediting_1588003(64901966, +), ADediting_1588004(64902565, +), ADediting_1588005(64902570, +), ADediting_1588006(64902680, +), ADediting_1588007(64904244, +), ADediting_1588008(64921690, +), ADediting_1588009(64927232, +),

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RNA editing positional annotations for ZNF273 using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_1344211	chr7_64894134_+	intergenic
ADediting_1344212	chr7_64894185_+	intergenic
ADediting_1344213	chr7_64894191_+	intergenic
ADediting_1344214	chr7_64894194_+	intergenic
ADediting_1344215	chr7_64894214_+	intergenic
ADediting_1344216	chr7_64894234_+	intergenic
ADediting_1344217	chr7_64894279_+	intergenic
ADediting_1344218	chr7_64894874_+	intergenic
ADediting_1344219	chr7_64894880_+	intergenic
ADediting_1344220	chr7_64894932_+	intergenic
ADediting_1344221	chr7_64894946_+	intergenic
ADediting_1344222	chr7_64894951_+	intergenic
ADediting_1344223	chr7_64894952_+	intergenic
ADediting_1344224	chr7_64895016_+	intergenic
ADediting_1344225	chr7_64895017_+	intergenic
ADediting_1344226	chr7_64895062_+	intergenic
ADediting_1344227	chr7_64897353_+	intergenic
ADediting_1344228	chr7_64897396_+	intergenic
ADediting_1344229	chr7_64897420_+	intergenic
ADediting_1344230	chr7_64897456_+	intergenic
ADediting_1344231	chr7_64897488_+	intergenic
ADediting_1344232	chr7_64897492_+	intergenic
ADediting_1344233	chr7_64897493_+	intergenic
ADediting_1344234	chr7_64897502_+	intergenic
ADediting_1344235	chr7_64897508_+	intergenic
ADediting_1344236	chr7_64897511_+	intergenic
ADediting_1344237	chr7_64897565_+	intergenic
ADediting_1344238	chr7_64897588_+	intergenic
ADediting_1344239	chr7_64897600_+	intergenic
ADediting_1344240	chr7_64897844_+	intergenic
ADediting_1344241	chr7_64897856_+	intergenic
ADediting_1344242	chr7_64897866_+	intergenic
ADediting_1344243	chr7_64897892_+	intergenic
ADediting_1344244	chr7_64897909_+	intergenic
ADediting_1344245	chr7_64897912_+	intergenic
ADediting_1344246	chr7_64897918_+	intergenic
ADediting_1344247	chr7_64897926_+	intergenic
ADediting_1344248	chr7_64897934_+	intergenic
ADediting_1344249	chr7_64897938_+	intergenic
ADediting_1344250	chr7_64897989_+	intergenic
ADediting_1344251	chr7_64898001_+	intergenic
ADediting_1344252	chr7_64899383_+	intergenic
ADediting_1344253	chr7_64899400_+	intergenic
ADediting_1344254	chr7_64899427_+	intergenic
ADediting_1344255	chr7_64899445_+	intergenic
ADediting_1344256	chr7_64899469_+	intergenic
ADediting_1344257	chr7_64899471_+	intergenic
ADediting_1344258	chr7_64899479_+	intergenic
ADediting_1344259	chr7_64899484_+	intergenic
ADediting_1344260	chr7_64899490_+	intergenic
ADediting_1344261	chr7_64899493_+	intergenic
ADediting_1344262	chr7_64899494_+	intergenic
ADediting_1344263	chr7_64899499_+	intergenic
ADediting_1344264	chr7_64899508_+	intergenic
ADediting_1344265	chr7_64899512_+	intergenic
ADediting_1344266	chr7_64899528_+	intergenic
ADediting_1344267	chr7_64899534_+	intergenic
ADediting_1344268	chr7_64899535_+	intergenic
ADediting_1344269	chr7_64899551_+	intergenic
ADediting_1344270	chr7_64899557_+	intergenic
ADediting_1344271	chr7_64899561_+	intergenic
ADediting_1344272	chr7_64899562_+	intergenic
ADediting_1344273	chr7_64899567_+	intergenic
ADediting_1344274	chr7_64899570_+	intergenic
ADediting_1344275	chr7_64899588_+	intergenic
ADediting_1344276	chr7_64899601_+	intergenic
ADediting_1344277	chr7_64899605_+	intergenic
ADediting_1344278	chr7_64899606_+	intergenic
ADediting_1344279	chr7_64899817_+	intergenic
ADediting_1344280	chr7_64899860_+	intergenic
ADediting_1344281	chr7_64899861_+	intergenic
ADediting_1344282	chr7_64899887_+	intergenic
ADediting_1344283	chr7_64899890_+	intergenic
ADediting_1344284	chr7_64899900_+	intergenic
ADediting_1344285	chr7_64899906_+	intergenic
ADediting_1344286	chr7_64899927_+	intergenic
ADediting_1344287	chr7_64899934_+	intergenic
ADediting_1344288	chr7_64899940_+	intergenic
ADediting_1344289	chr7_64899969_+	intergenic
ADediting_1344290	chr7_64899988_+	intergenic
ADediting_1344291	chr7_64900239_+	intergenic
ADediting_1344292	chr7_64900306_+	intergenic
ADediting_1344293	chr7_64900309_+	intergenic
ADediting_1344294	chr7_64900360_+	intergenic
ADediting_1344295	chr7_64900361_+	intergenic
ADediting_1344296	chr7_64901103_+	intergenic
ADediting_1344297	chr7_64901113_+	intergenic
ADediting_1344298	chr7_64901115_+	intergenic
ADediting_1344299	chr7_64901120_+	intergenic
ADediting_1344300	chr7_64901142_+	intergenic
ADediting_1344301	chr7_64901145_+	intergenic
ADediting_1344302	chr7_64901158_+	intergenic
ADediting_1344303	chr7_64901160_+	intergenic
ADediting_1344304	chr7_64901168_+	intergenic
ADediting_1344305	chr7_64901169_+	intergenic
ADediting_1344306	chr7_64901183_+	intergenic
ADediting_1344307	chr7_64901225_+	intergenic
ADediting_1344308	chr7_64901695_+	intergenic
ADediting_1344309	chr7_64901696_+	intergenic
ADediting_1344310	chr7_64901701_+	intergenic
ADediting_1344311	chr7_64901786_+	intergenic
ADediting_1344312	chr7_64901803_+	intergenic
ADediting_1344313	chr7_64901829_+	intergenic
ADediting_1344314	chr7_64901830_+	intergenic
ADediting_1344315	chr7_64901839_+	intergenic
ADediting_1344316	chr7_64901859_+	intergenic
ADediting_1344317	chr7_64901862_+	intergenic
ADediting_1344318	chr7_64902452_+	upstream
ADediting_1344319	chr7_64902510_+	upstream
ADediting_1344320	chr7_64902515_+	upstream
ADediting_1344321	chr7_64902520_+	upstream
ADediting_1344322	chr7_64902528_+	upstream
ADediting_1344323	chr7_64902529_+	upstream
ADediting_1344324	chr7_64902544_+	upstream
ADediting_1344325	chr7_64902554_+	upstream
ADediting_1344326	chr7_64902574_+	upstream
ADediting_1344327	chr7_64902583_+	upstream
ADediting_1344328	chr7_64902591_+	upstream
ADediting_1344329	chr7_64902604_+	upstream
ADediting_1344330	chr7_64902608_+	upstream
ADediting_1344331	chr7_64902641_+	upstream
ADediting_1344332	chr7_64902650_+	upstream
ADediting_1344333	chr7_64904119_+	intronic
ADediting_1344334	chr7_64904144_+	intronic
ADediting_1344335	chr7_64904163_+	intronic
ADediting_1344336	chr7_64904192_+	intronic
ADediting_1344337	chr7_64904193_+	intronic
ADediting_1344338	chr7_64904270_+	intronic
ADediting_1344339	chr7_64904273_+	intronic
ADediting_1344340	chr7_64904324_+	intronic
ADediting_1344341	chr7_64904358_+	intronic
ADediting_1344342	chr7_64905215_+	intronic
ADediting_1344343	chr7_64905216_+	intronic
ADediting_1344344	chr7_64905233_+	intronic
ADediting_1344345	chr7_64905299_+	intronic
ADediting_1344346	chr7_64905351_+	intronic
ADediting_1344347	chr7_64905363_+	intronic
ADediting_1344351	chr7_64915941_+	intronic
ADediting_1344352	chr7_64915971_+	intronic
ADediting_1344353	chr7_64915972_+	intronic
ADediting_1344354	chr7_64915994_+	intronic
ADediting_1344355	chr7_64915995_+	intronic
ADediting_1344356	chr7_64916040_+	intronic
ADediting_1344357	chr7_64916049_+	intronic
ADediting_1344358	chr7_64916085_+	intronic
ADediting_1344359	chr7_64916088_+	intronic
ADediting_1344360	chr7_64916102_+	intronic
ADediting_1344361	chr7_64916128_+	intronic
ADediting_1344362	chr7_64916457_+	intronic
ADediting_1344363	chr7_64918452_+	intronic
ADediting_1344364	chr7_64918505_+	intronic
ADediting_1344365	chr7_64918514_+	intronic
ADediting_1344366	chr7_64918540_+	intronic
ADediting_1344367	chr7_64919369_+	intronic
ADediting_1344368	chr7_64919548_+	intronic
ADediting_1344369	chr7_64921121_+	intronic
ADediting_1344370	chr7_64921164_+	intronic
ADediting_1344371	chr7_64921165_+	intronic
ADediting_1344372	chr7_64921169_+	intronic
ADediting_1344373	chr7_64921286_+	intronic
ADediting_1344374	chr7_64921679_+	intronic
ADediting_1344375	chr7_64921726_+	intronic
ADediting_1344376	chr7_64922393_+	intronic
ADediting_1344377	chr7_64922409_+	intronic
ADediting_1344378	chr7_64922429_+	intronic
ADediting_1344379	chr7_64922492_+	intronic
ADediting_1344380	chr7_64922547_+	intronic
ADediting_1344381	chr7_64922564_+	intronic
ADediting_1344382	chr7_64922586_+	intronic
ADediting_1344383	chr7_64922740_+	intronic
ADediting_1344384	chr7_64922769_+	intronic
ADediting_1344385	chr7_64922779_+	intronic
ADediting_1344386	chr7_64922789_+	intronic
ADediting_1344387	chr7_64922803_+	intronic
ADediting_1344388	chr7_64922809_+	intronic
ADediting_1344389	chr7_64922823_+	intronic
ADediting_1344390	chr7_64922886_+	intronic
ADediting_1344391	chr7_64922891_+	intronic
ADediting_1344392	chr7_64922915_+	intronic
ADediting_1344393	chr7_64922916_+	intronic
ADediting_1344394	chr7_64922941_+	intronic
ADediting_1344395	chr7_64923421_+	intronic
ADediting_1344396	chr7_64923441_+	intronic
ADediting_1344397	chr7_64923442_+	intronic
ADediting_1344398	chr7_64923525_+	intronic
ADediting_1344399	chr7_64923571_+	intronic
ADediting_1344400	chr7_64927149_+	intronic
ADediting_1344401	chr7_64927162_+	intronic
ADediting_1344402	chr7_64927193_+	intronic
ADediting_1344403	chr7_64927222_+	intronic
ADediting_1344404	chr7_64929936_+	UTR3
ADediting_1344405	chr7_64930006_+	UTR3
ADediting_1344406	chr7_64930047_+	UTR3
ADediting_1344407	chr7_64930053_+	UTR3
ADediting_1587993	chr7_64897540_+	intergenic
ADediting_1587994	chr7_64899422_+	intergenic
ADediting_1587995	chr7_64899435_+	intergenic
ADediting_1587996	chr7_64899497_+	intergenic
ADediting_1587997	chr7_64899505_+	intergenic
ADediting_1587998	chr7_64899585_+	intergenic
ADediting_1587999	chr7_64900264_+	intergenic
ADediting_1588000	chr7_64900292_+	intergenic
ADediting_1588001	chr7_64900335_+	intergenic
ADediting_1588002	chr7_64901039_+	intergenic
ADediting_1588003	chr7_64901966_+	intergenic
ADediting_1588004	chr7_64902565_+	upstream
ADediting_1588005	chr7_64902570_+	upstream
ADediting_1588006	chr7_64902680_+	upstream
ADediting_1588007	chr7_64904244_+	intronic
ADediting_1588008	chr7_64921690_+	intronic
ADediting_1588009	chr7_64927232_+	intronic

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_1344211	chr7_64894134_+	SINE	Alu	Name=AluSz
ADediting_1344212	chr7_64894185_+	SINE	Alu	Name=AluSz
ADediting_1344213	chr7_64894191_+	SINE	Alu	Name=AluSz
ADediting_1344214	chr7_64894194_+	SINE	Alu	Name=AluSz
ADediting_1344215	chr7_64894214_+	SINE	Alu	Name=AluSz
ADediting_1344216	chr7_64894234_+	SINE	Alu	Name=AluSz
ADediting_1344217	chr7_64894279_+	SINE	Alu	Name=AluSz
ADediting_1344218	chr7_64894874_+	SINE	Alu	Name=AluSx3
ADediting_1344219	chr7_64894880_+	SINE	Alu	Name=AluSx3
ADediting_1344220	chr7_64894932_+	SINE	Alu	Name=AluSx3
ADediting_1344221	chr7_64894946_+	SINE	Alu	Name=AluSx3
ADediting_1344222	chr7_64894951_+	SINE	Alu	Name=AluSx3
ADediting_1344223	chr7_64894952_+	SINE	Alu	Name=AluSx3
ADediting_1344224	chr7_64895016_+	SINE	Alu	Name=AluSx3
ADediting_1344225	chr7_64895017_+	SINE	Alu	Name=AluSx3
ADediting_1344226	chr7_64895062_+	SINE	Alu	Name=AluSx3
ADediting_1344227	chr7_64897353_+	SINE	Alu	Name=AluY
ADediting_1344228	chr7_64897396_+	SINE	Alu	Name=AluY
ADediting_1344229	chr7_64897420_+	SINE	Alu	Name=AluY
ADediting_1344230	chr7_64897456_+	SINE	Alu	Name=AluY
ADediting_1344231	chr7_64897488_+	SINE	Alu	Name=AluY
ADediting_1344232	chr7_64897492_+	SINE	Alu	Name=AluY
ADediting_1344233	chr7_64897493_+	SINE	Alu	Name=AluY
ADediting_1344234	chr7_64897502_+	SINE	Alu	Name=AluY
ADediting_1344235	chr7_64897508_+	SINE	Alu	Name=AluY
ADediting_1344236	chr7_64897511_+	SINE	Alu	Name=AluY
ADediting_1344237	chr7_64897565_+	SINE	Alu	Name=AluY
ADediting_1344238	chr7_64897588_+	SINE	Alu	Name=AluY
ADediting_1344239	chr7_64897600_+	SINE	Alu	Name=AluY
ADediting_1344240	chr7_64897844_+	SINE	Alu	Name=AluY
ADediting_1344241	chr7_64897856_+	SINE	Alu	Name=AluY
ADediting_1344242	chr7_64897866_+	SINE	Alu	Name=AluY
ADediting_1344243	chr7_64897892_+	SINE	Alu	Name=AluY
ADediting_1344244	chr7_64897909_+	SINE	Alu	Name=AluY
ADediting_1344245	chr7_64897912_+	SINE	Alu	Name=AluY
ADediting_1344246	chr7_64897918_+	SINE	Alu	Name=AluY
ADediting_1344247	chr7_64897926_+	SINE	Alu	Name=AluY
ADediting_1344248	chr7_64897934_+	SINE	Alu	Name=AluY
ADediting_1344249	chr7_64897938_+	SINE	Alu	Name=AluY
ADediting_1344250	chr7_64897989_+	SINE	Alu	Name=AluY
ADediting_1344251	chr7_64898001_+	SINE	Alu	Name=AluY
ADediting_1344252	chr7_64899383_+	SINE	Alu	Name=AluSz
ADediting_1344253	chr7_64899400_+	SINE	Alu	Name=AluSz
ADediting_1344254	chr7_64899427_+	SINE	Alu	Name=AluSz
ADediting_1344255	chr7_64899445_+	SINE	Alu	Name=AluSz
ADediting_1344256	chr7_64899469_+	SINE	Alu	Name=AluSz
ADediting_1344257	chr7_64899471_+	SINE	Alu	Name=AluSz
ADediting_1344258	chr7_64899479_+	SINE	Alu	Name=AluSz
ADediting_1344259	chr7_64899484_+	SINE	Alu	Name=AluSz
ADediting_1344260	chr7_64899490_+	SINE	Alu	Name=AluSz
ADediting_1344261	chr7_64899493_+	SINE	Alu	Name=AluSz
ADediting_1344262	chr7_64899494_+	SINE	Alu	Name=AluSz
ADediting_1344263	chr7_64899499_+	SINE	Alu	Name=AluSz
ADediting_1344264	chr7_64899508_+	SINE	Alu	Name=AluSz
ADediting_1344265	chr7_64899512_+	SINE	Alu	Name=AluSz
ADediting_1344266	chr7_64899528_+	SINE	Alu	Name=AluSz
ADediting_1344267	chr7_64899534_+	SINE	Alu	Name=AluSz
ADediting_1344268	chr7_64899535_+	SINE	Alu	Name=AluSz
ADediting_1344269	chr7_64899551_+	SINE	Alu	Name=AluSz
ADediting_1344270	chr7_64899557_+	SINE	Alu	Name=AluSz
ADediting_1344271	chr7_64899561_+	SINE	Alu	Name=AluSz
ADediting_1344272	chr7_64899562_+	SINE	Alu	Name=AluSz
ADediting_1344273	chr7_64899567_+	SINE	Alu	Name=AluSz
ADediting_1344274	chr7_64899570_+	SINE	Alu	Name=AluSz
ADediting_1344275	chr7_64899588_+	SINE	Alu	Name=AluSz
ADediting_1344276	chr7_64899601_+	SINE	Alu	Name=AluSz
ADediting_1344277	chr7_64899605_+	SINE	Alu	Name=AluSz
ADediting_1344278	chr7_64899606_+	SINE	Alu	Name=AluSz
ADediting_1344279	chr7_64899817_+	SINE	Alu	Name=AluSp
ADediting_1344280	chr7_64899860_+	SINE	Alu	Name=AluSp
ADediting_1344281	chr7_64899861_+	SINE	Alu	Name=AluSp
ADediting_1344282	chr7_64899887_+	SINE	Alu	Name=AluSp
ADediting_1344283	chr7_64899890_+	SINE	Alu	Name=AluSp
ADediting_1344284	chr7_64899900_+	SINE	Alu	Name=AluSp
ADediting_1344285	chr7_64899906_+	SINE	Alu	Name=AluSp
ADediting_1344286	chr7_64899927_+	SINE	Alu	Name=AluSp
ADediting_1344287	chr7_64899934_+	SINE	Alu	Name=AluSp
ADediting_1344288	chr7_64899940_+	SINE	Alu	Name=AluSp
ADediting_1344289	chr7_64899969_+	SINE	Alu	Name=AluSp
ADediting_1344290	chr7_64899988_+	SINE	Alu	Name=AluSp
ADediting_1344291	chr7_64900239_+	SINE	Alu	Name=AluSz6
ADediting_1344292	chr7_64900306_+	SINE	Alu	Name=AluSz6
ADediting_1344293	chr7_64900309_+	SINE	Alu	Name=AluSz6
ADediting_1344294	chr7_64900360_+	SINE	Alu	Name=AluSz6
ADediting_1344295	chr7_64900361_+	SINE	Alu	Name=AluSz6
ADediting_1344296	chr7_64901103_+	SINE	Alu	Name=AluSx
ADediting_1344297	chr7_64901113_+	SINE	Alu	Name=AluSx
ADediting_1344298	chr7_64901115_+	SINE	Alu	Name=AluSx
ADediting_1344299	chr7_64901120_+	SINE	Alu	Name=AluSx
ADediting_1344300	chr7_64901142_+	SINE	Alu	Name=AluSx
ADediting_1344301	chr7_64901145_+	SINE	Alu	Name=AluSx
ADediting_1344302	chr7_64901158_+	SINE	Alu	Name=AluSx
ADediting_1344303	chr7_64901160_+	SINE	Alu	Name=AluSx
ADediting_1344304	chr7_64901168_+	SINE	Alu	Name=AluSx
ADediting_1344305	chr7_64901169_+	SINE	Alu	Name=AluSx
ADediting_1344306	chr7_64901183_+	SINE	Alu	Name=AluSx
ADediting_1344307	chr7_64901225_+	SINE	Alu	Name=AluSx
ADediting_1344308	chr7_64901695_+	SINE	Alu	Name=AluSp
ADediting_1344309	chr7_64901696_+	SINE	Alu	Name=AluSp
ADediting_1344310	chr7_64901701_+	SINE	Alu	Name=AluSp
ADediting_1344311	chr7_64901786_+	SINE	Alu	Name=AluSp
ADediting_1344312	chr7_64901803_+	SINE	Alu	Name=AluSp
ADediting_1344313	chr7_64901829_+	SINE	Alu	Name=AluSp
ADediting_1344314	chr7_64901830_+	SINE	Alu	Name=AluSp
ADediting_1344315	chr7_64901839_+	SINE	Alu	Name=AluSp
ADediting_1344316	chr7_64901859_+	SINE	Alu	Name=AluSp
ADediting_1344317	chr7_64901862_+	SINE	Alu	Name=AluSp
ADediting_1344318	chr7_64902452_+	SINE	Alu	Name=AluSx
ADediting_1344319	chr7_64902510_+	SINE	Alu	Name=AluSx
ADediting_1344320	chr7_64902515_+	SINE	Alu	Name=AluSx
ADediting_1344321	chr7_64902520_+	SINE	Alu	Name=AluSx
ADediting_1344322	chr7_64902528_+	SINE	Alu	Name=AluSx
ADediting_1344323	chr7_64902529_+	SINE	Alu	Name=AluSx
ADediting_1344324	chr7_64902544_+	SINE	Alu	Name=AluSx
ADediting_1344325	chr7_64902554_+	SINE	Alu	Name=AluSx
ADediting_1344326	chr7_64902574_+	SINE	Alu	Name=AluSx
ADediting_1344327	chr7_64902583_+	SINE	Alu	Name=AluSx
ADediting_1344328	chr7_64902591_+	SINE	Alu	Name=AluSx
ADediting_1344329	chr7_64902604_+	SINE	Alu	Name=AluSx
ADediting_1344330	chr7_64902608_+	SINE	Alu	Name=AluSx
ADediting_1344331	chr7_64902641_+	SINE	Alu	Name=AluSx
ADediting_1344332	chr7_64902650_+	SINE	Alu	Name=AluSx
ADediting_1344333	chr7_64904119_+	SINE	Alu	Name=AluSx
ADediting_1344334	chr7_64904144_+	SINE	Alu	Name=AluSx
ADediting_1344335	chr7_64904163_+	SINE	Alu	Name=AluSx
ADediting_1344336	chr7_64904192_+	SINE	Alu	Name=AluSx
ADediting_1344337	chr7_64904193_+	SINE	Alu	Name=AluSx
ADediting_1344338	chr7_64904270_+	SINE	Alu	Name=AluSx
ADediting_1344339	chr7_64904273_+	SINE	Alu	Name=AluSx
ADediting_1344340	chr7_64904324_+	SINE	Alu	Name=AluSx
ADediting_1344341	chr7_64904358_+	SINE	Alu	Name=AluSx
ADediting_1344342	chr7_64905215_+	SINE	Alu	Name=AluSz
ADediting_1344343	chr7_64905216_+	SINE	Alu	Name=AluSz
ADediting_1344344	chr7_64905233_+	SINE	Alu	Name=AluSz
ADediting_1344345	chr7_64905299_+	SINE	Alu	Name=AluSz
ADediting_1344346	chr7_64905351_+	SINE	Alu	Name=AluSz
ADediting_1344347	chr7_64905363_+	SINE	Alu	Name=AluSz
ADediting_1344351	chr7_64915941_+	SINE	Alu	Name=AluSx
ADediting_1344352	chr7_64915971_+	SINE	Alu	Name=AluSx
ADediting_1344353	chr7_64915972_+	SINE	Alu	Name=AluSx
ADediting_1344354	chr7_64915994_+	SINE	Alu	Name=AluSx
ADediting_1344355	chr7_64915995_+	SINE	Alu	Name=AluSx
ADediting_1344356	chr7_64916040_+	SINE	Alu	Name=AluSx
ADediting_1344357	chr7_64916049_+	SINE	Alu	Name=AluSx
ADediting_1344358	chr7_64916085_+	SINE	Alu	Name=AluSx
ADediting_1344359	chr7_64916088_+	SINE	Alu	Name=AluSx
ADediting_1344360	chr7_64916102_+	SINE	Alu	Name=AluSx
ADediting_1344361	chr7_64916128_+	SINE	Alu	Name=AluSx
ADediting_1344362	chr7_64916457_+	SINE	Alu	Name=AluSq2
ADediting_1344363	chr7_64918452_+	SINE	Alu	Name=AluSc
ADediting_1344364	chr7_64918505_+	SINE	Alu	Name=AluSc
ADediting_1344365	chr7_64918514_+	SINE	Alu	Name=AluSc
ADediting_1344366	chr7_64918540_+	SINE	Alu	Name=AluSc
ADediting_1344367	chr7_64919369_+	SINE	Alu	Name=AluSz
ADediting_1344368	chr7_64919548_+	SINE	Alu	Name=AluSz
ADediting_1344369	chr7_64921121_+	SINE	Alu	Name=AluSq2
ADediting_1344370	chr7_64921164_+	SINE	Alu	Name=AluSq2
ADediting_1344371	chr7_64921165_+	SINE	Alu	Name=AluSq2
ADediting_1344372	chr7_64921169_+	SINE	Alu	Name=AluSq2
ADediting_1344373	chr7_64921286_+	SINE	Alu	Name=AluSq2
ADediting_1344374	chr7_64921679_+	SINE	Alu	Name=AluSx1
ADediting_1344375	chr7_64921726_+	SINE	Alu	Name=AluSx1
ADediting_1344376	chr7_64922393_+	SINE	Alu	Name=AluSz
ADediting_1344377	chr7_64922409_+	SINE	Alu	Name=AluSz
ADediting_1344378	chr7_64922429_+	SINE	Alu	Name=AluSz
ADediting_1344379	chr7_64922492_+	SINE	Alu	Name=AluSz
ADediting_1344380	chr7_64922547_+	SINE	Alu	Name=AluSz
ADediting_1344381	chr7_64922564_+	SINE	Alu	Name=AluSz
ADediting_1344382	chr7_64922586_+	SINE	Alu	Name=AluSz
ADediting_1344383	chr7_64922740_+	SINE	Alu	Name=AluSx
ADediting_1344384	chr7_64922769_+	SINE	Alu	Name=AluSx
ADediting_1344385	chr7_64922779_+	SINE	Alu	Name=AluSx
ADediting_1344386	chr7_64922789_+	SINE	Alu	Name=AluSx
ADediting_1344387	chr7_64922803_+	SINE	Alu	Name=AluSx
ADediting_1344388	chr7_64922809_+	SINE	Alu	Name=AluSx
ADediting_1344389	chr7_64922823_+	SINE	Alu	Name=AluSx
ADediting_1344390	chr7_64922886_+	SINE	Alu	Name=AluSx
ADediting_1344391	chr7_64922891_+	SINE	Alu	Name=AluSx
ADediting_1344392	chr7_64922915_+	SINE	Alu	Name=AluSx
ADediting_1344393	chr7_64922916_+	SINE	Alu	Name=AluSx
ADediting_1344394	chr7_64922941_+	SINE	Alu	Name=AluSx
ADediting_1344395	chr7_64923421_+	SINE	Alu	Name=AluSx
ADediting_1344396	chr7_64923441_+	SINE	Alu	Name=AluSx
ADediting_1344397	chr7_64923442_+	SINE	Alu	Name=AluSx
ADediting_1344398	chr7_64923525_+	SINE	Alu	Name=AluSx
ADediting_1344399	chr7_64923571_+	SINE	Alu	Name=AluSx
ADediting_1344400	chr7_64927149_+	SINE	Alu	Name=AluSg
ADediting_1344401	chr7_64927162_+	SINE	Alu	Name=AluSg
ADediting_1344402	chr7_64927193_+	SINE	Alu	Name=AluSg
ADediting_1344403	chr7_64927222_+	SINE	Alu	Name=AluSg
ADediting_1344404	chr7_64929936_+	SINE	Alu	Name=AluSp
ADediting_1344405	chr7_64930006_+	SINE	Alu	Name=AluSp
ADediting_1344406	chr7_64930047_+	SINE	Alu	Name=AluSp
ADediting_1344407	chr7_64930053_+	SINE	Alu	Name=AluSp
ADediting_1587993	chr7_64897540_+	SINE	Alu	Name=AluY
ADediting_1587994	chr7_64899422_+	SINE	Alu	Name=AluSz
ADediting_1587995	chr7_64899435_+	SINE	Alu	Name=AluSz
ADediting_1587996	chr7_64899497_+	SINE	Alu	Name=AluSz
ADediting_1587997	chr7_64899505_+	SINE	Alu	Name=AluSz
ADediting_1587998	chr7_64899585_+	SINE	Alu	Name=AluSz
ADediting_1587999	chr7_64900264_+	SINE	Alu	Name=AluSz6
ADediting_1588000	chr7_64900292_+	SINE	Alu	Name=AluSz6
ADediting_1588001	chr7_64900335_+	SINE	Alu	Name=AluSz6
ADediting_1588002	chr7_64901039_+	SINE	Alu	Name=AluSx
ADediting_1588003	chr7_64901966_+	SINE	Alu	Name=AluSz
ADediting_1588004	chr7_64902565_+	SINE	Alu	Name=AluSx
ADediting_1588005	chr7_64902570_+	SINE	Alu	Name=AluSx
ADediting_1588006	chr7_64902680_+	SINE	Alu	Name=AluSx
ADediting_1588007	chr7_64904244_+	SINE	Alu	Name=AluSx
ADediting_1588008	chr7_64921690_+	SINE	Alu	Name=AluSx1
ADediting_1588009	chr7_64927232_+	SINE	Alu	Name=AluSg

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RNA A-to-I editing events in the alternative splicing sites for ZNF273

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

ADeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF273

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

Top

Protein coding region RNA A-to-I editings for ZNF273

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for ZNF273

RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_1344227	chr7_64897353_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4432	chr7	64897351	64897357	7mer-m8	64893889	64897358	146	-13.78
ADediting_1344228	chr7_64897396_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4537	chr7	64897394	64897401	8mer-1a	64897379	64897401	151	-25.6
ADediting_1344230	chr7_64897456_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4691-3p	chr7	64897454	64897460	7mer-m8	64897434	64897461	150	-26.36
ADediting_1344232	chr7_64897492_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-1207-3p	chr7	64897486	64897493	8mer-1a	64897476	64897493	140	-14.68
ADediting_1344232	chr7_64897492_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-34a-3p	chr7	64897489	64897495	7mer-m8	64897474	64897496	143	-8.12
ADediting_1344233	chr7_64897493_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4661-5p	chr7	64897488	64897494	7mer-m8	64897474	64897495	149	-18.5
ADediting_1344233	chr7_64897493_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-548ae-3p	chr7	64897492	64897498	7mer-m8	64897479	64897499	141	-6.06
ADediting_1344233	chr7_64897493_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-548ah-3p	chr7	64897492	64897498	7mer-m8	64897477	64897499	143	-6.06
ADediting_1344233	chr7_64897493_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-548aj-3p	chr7	64897492	64897498	7mer-m8	64897479	64897499	141	-6.96
ADediting_1344233	chr7_64897493_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-548am-3p	chr7	64897492	64897498	7mer-m8	64897477	64897499	143	-6.06
ADediting_1344233	chr7_64897493_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-548aq-3p	chr7	64897492	64897498	7mer-m8	64897478	64897499	141	-6.06
ADediting_1344233	chr7_64897493_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-548j-3p	chr7	64897492	64897498	7mer-m8	64897479	64897499	141	-6.06
ADediting_1344233	chr7_64897493_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-548x-3p	chr7	64897492	64897498	7mer-m8	64897480	64897499	141	-6.96
ADediting_1344233	chr7_64897493_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-7844-5p	chr7	64897490	64897496	7mer-m8	64897476	64897497	168	-22.99
ADediting_1344237	chr7_64897565_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4776-5p	chr7	64897563	64897569	7mer-m8	64897549	64897570	156	-23.71
ADediting_1344237	chr7_64897565_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4800-5p	chr7	64897564	64897570	7mer-m8	64897548	64897571	147	-23.73
ADediting_1344238	chr7_64897588_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-3189-3p	chr7	64897583	64897589	7mer-m8	64897567	64897590	153	-24.71
ADediting_1344238	chr7_64897588_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-6813-3p	chr7	64897584	64897590	7mer-m8	64897571	64897591	140	-12.55
ADediting_1344240	chr7_64897844_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-6089	chr7	64897843	64897849	7mer-m8	64897827	64897850	164	-39.05
ADediting_1344241	chr7_64897856_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4691-3p	chr7	64897854	64897860	7mer-m8	64897834	64897861	155	-28.26
ADediting_1344242	chr7_64897866_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-17-3p	chr7	64897863	64897869	7mer-m8	64897848	64897870	154	-20.36
ADediting_1344243	chr7_64897892_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-34a-3p	chr7	64897889	64897895	7mer-m8	64897875	64897896	140	-8.35
ADediting_1344244	chr7_64897909_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-3613-3p	chr7	64897903	64897909	7mer-m8	64897884	64897910	147	-10.11
ADediting_1344246	chr7_64897918_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-340-3p	chr7	64897913	64897919	7mer-m8	64897899	64897920	152	-16.58
ADediting_1344246	chr7_64897918_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-6827-3p	chr7	64897913	64897919	7mer-m8	64897900	64897920	153	-17.53
ADediting_1344248	chr7_64897934_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-3190-5p	chr7	64897933	64897939	7mer-m8	64897922	64897940	152	-22.63
ADediting_1344248	chr7_64897934_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-548s	chr7	64897932	64897938	7mer-m8	64897915	64897939	151	-15.32
ADediting_1344250	chr7_64897989_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-3189-3p	chr7	64897984	64897990	7mer-m8	64897969	64897991	149	-24.47
ADediting_1344250	chr7_64897989_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-6813-3p	chr7	64897985	64897991	7mer-m8	64897972	64897992	140	-12.55
ADediting_1344395	chr7_64923421_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-17-3p	chr7	64923415	64923421	7mer-m8	64923401	64923422	146	-16.38
ADediting_1344395	chr7_64923421_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-485-5p	chr7	64923419	64923425	7mer-m8	64923406	64923426	150	-17.92
ADediting_1344395	chr7_64923421_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-6884-5p	chr7	64923419	64923425	7mer-m8	64923404	64923426	146	-19.8
ADediting_1344397	chr7_64923442_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-3140-5p	chr7	64923437	64923443	7mer-m8	64923424	64923444	146	-13.93
ADediting_1344397	chr7_64923442_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-3622a-3p	chr7	64923439	64923446	8mer-1a	64923425	64923446	149	-19.91
ADediting_1344397	chr7_64923442_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-3622b-3p	chr7	64923439	64923446	8mer-1a	64923427	64923446	159	-26.27
ADediting_1344397	chr7_64923442_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-5187-3p	chr7	64923436	64923442	7mer-m8	64923423	64923443	146	-14.71
ADediting_1344399	chr7_64923571_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-4755-3p	chr7	64923566	64923572	7mer-m8	64923552	64923573	144	-19.64

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_1344228	chr7_64897396_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-3160-3p	chr7	64897394	64897401	8mer-1a	64897380	64897401	152	-19.51
ADediting_1344229	chr7_64897420_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-1273h-5p	chr7	64897414	64897420	7mer-m8	64897402	64897421	154	-24.88
ADediting_1344229	chr7_64897420_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-3689a-3p	chr7	64897414	64897420	7mer-m8	64897401	64897421	144	-19.41
ADediting_1344229	chr7_64897420_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-3689b-3p	chr7	64897414	64897420	7mer-m8	64897401	64897421	152	-22.4
ADediting_1344229	chr7_64897420_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-3689c	chr7	64897414	64897420	7mer-m8	64897401	64897421	152	-22.4
ADediting_1344229	chr7_64897420_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4738-3p	chr7	64897419	64897426	8mer-1a	64897400	64897426	155	-22.36
ADediting_1344229	chr7_64897420_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-6780a-5p	chr7	64897414	64897420	7mer-m8	64897402	64897421	152	-24.66
ADediting_1344230	chr7_64897456_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-5690	chr7	64897454	64897460	7mer-m8	64897441	64897461	145	-16.75
ADediting_1344231	chr7_64897488_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-5589-5p	chr7	64897484	64897490	7mer-m8	64897471	64897491	149	-18.88
ADediting_1344240	chr7_64897844_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4329	chr7	64897839	64897845	7mer-m8	64897828	64897846	141	-10.68
ADediting_1344240	chr7_64897844_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4478	chr7	64897842	64897848	7mer-m8	64897833	64897849	151	-27.88
ADediting_1344240	chr7_64897844_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-485-5p	chr7	64897843	64897849	7mer-m8	64897829	64897850	153	-18.28
ADediting_1344241	chr7_64897856_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-5690	chr7	64897854	64897860	7mer-m8	64897841	64897861	145	-16.75
ADediting_1344242	chr7_64897866_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-20b-3p	chr7	64897863	64897869	7mer-m8	64897848	64897870	153	-18.18
ADediting_1344245	chr7_64897912_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4684-5p	chr7	64897910	64897916	7mer-m8	64897894	64897917	155	-14.98
ADediting_1344246	chr7_64897918_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-10a-5p	chr7	64897916	64897922	7mer-m8	64897901	64897923	145	-13.67
ADediting_1344246	chr7_64897918_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-10b-5p	chr7	64897916	64897922	7mer-m8	64897901	64897923	140	-12.49
ADediting_1344246	chr7_64897918_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-339-5p	chr7	64897915	64897921	7mer-m8	64897897	64897922	150	-18.37
ADediting_1344246	chr7_64897918_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4421	chr7	64897914	64897920	7mer-m8	64897900	64897921	155	-17.44
ADediting_1344246	chr7_64897918_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-5699-3p	chr7	64897914	64897920	7mer-m8	64897900	64897921	153	-17.34
ADediting_1344246	chr7_64897918_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-6818-3p	chr7	64897912	64897918	7mer-m8	64897898	64897919	140	-12.78
ADediting_1344248	chr7_64897934_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4794	chr7	64897933	64897939	7mer-m8	64897918	64897940	151	-21.79
ADediting_1344248	chr7_64897934_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-664a-5p	chr7	64897933	64897939	7mer-m8	64897917	64897940	141	-16.24
ADediting_1344249	chr7_64897938_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4793-5p	chr7	64897937	64897943	7mer-m8	64897921	64897944	154	-20.69
ADediting_1344249	chr7_64897938_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-4794	chr7	64897933	64897939	7mer-m8	64897918	64897940	151	-21.79
ADediting_1344249	chr7_64897938_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-664a-5p	chr7	64897933	64897939	7mer-m8	64897917	64897940	141	-16.24
ADediting_1344251	chr7_64898001_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-2054	chr7	64897997	64898003	7mer-m8	64897980	64898004	146	-11.94
ADediting_1344395	chr7_64923421_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-377-5p	chr7	64923419	64923425	7mer-m8	64923405	64923426	147	-17.97
ADediting_1344395	chr7_64923421_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-6086	chr7	64923419	64923425	7mer-m8	64923406	64923426	145	-15.82
ADediting_1344395	chr7_64923421_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-6516-5p	chr7	64923415	64923421	7mer-m8	64923401	64923422	155	-14.94
ADediting_1344396	chr7_64923441_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-3614-5p	chr7	64923440	64923446	7mer-1a	64923424	64923446	149	-21.45
ADediting_1344397	chr7_64923442_+	ENSG00000198039.11	ENST00000489672.5	ZNF273-206	hsa-miR-3614-5p	chr7	64923440	64923446	7mer-1a	64923424	64923446	149	-21.45
ADediting_1587993	chr7_64897540_+	ENSG00000198039.11	ENST00000527278.5	ZNF273-207	hsa-miR-591	chr7	64897539	64897545	7mer-m8	64897525	64897546	144	-17.41

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_291761

chr11_93733708_-

ENSG00000198039.11

ENST00000476120.1

ZNF273-204

hsa-miR-1304-3p

chr7

64929219

64929225

7mer-m8

64929205

64929226

140

-13.38

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

Differentially expressed lncRNA-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for ZNF273

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000527278.5	lncRNA
ENST00000489672.5	lncRNA

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in lncRNA.

ADeditom_ID	ENST	Editing_Information	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
ADediting_1344227	ENST00000527278.5	chr7_64897353_+	494	-824.60	-820.40	-857.80
ADediting_1344228	ENST00000527278.5	chr7_64897396_+	537	-820.40	-820.40	-857.80
ADediting_1344229	ENST00000527278.5	chr7_64897420_+	561	-820.20	-820.40	-857.80
ADediting_1344230	ENST00000527278.5	chr7_64897456_+	597	-821.00	-820.40	-857.80
ADediting_1344231	ENST00000527278.5	chr7_64897488_+	629	-819.70	-820.40	-857.80
ADediting_1344232	ENST00000527278.5	chr7_64897492_+	633	-820.10	-820.40	-857.80
ADediting_1344233	ENST00000527278.5	chr7_64897493_+	634	-820.40	-820.40	-857.80
ADediting_1344234	ENST00000527278.5	chr7_64897502_+	643	-819.90	-820.40	-857.80
ADediting_1344235	ENST00000527278.5	chr7_64897508_+	649	-823.70	-820.40	-857.80
ADediting_1344236	ENST00000527278.5	chr7_64897511_+	652	-821.20	-820.40	-857.80
ADediting_1587993	ENST00000527278.5	chr7_64897540_+	681	-822.80	-820.40	-857.80
ADediting_1344237	ENST00000527278.5	chr7_64897565_+	706	-821.60	-820.40	-857.80
ADediting_1344238	ENST00000527278.5	chr7_64897588_+	729	-826.30	-820.40	-857.80
ADediting_1344239	ENST00000527278.5	chr7_64897600_+	741	-820.40	-820.40	-857.80
ADediting_1344240	ENST00000527278.5	chr7_64897844_+	985	-821.30	-820.40	-857.80
ADediting_1344241	ENST00000527278.5	chr7_64897856_+	997	-823.10	-820.40	-857.80
ADediting_1344242	ENST00000527278.5	chr7_64897866_+	1007	-822.20	-820.40	-857.80
ADediting_1344243	ENST00000527278.5	chr7_64897892_+	1033	-820.10	-820.40	-857.80
ADediting_1344244	ENST00000527278.5	chr7_64897909_+	1050	-823.60	-820.40	-857.80
ADediting_1344245	ENST00000527278.5	chr7_64897912_+	1053	-821.40	-820.40	-857.80
ADediting_1344246	ENST00000527278.5	chr7_64897918_+	1059	-821.30	-820.40	-857.80
ADediting_1344247	ENST00000527278.5	chr7_64897926_+	1067	-821.40	-820.40	-857.80
ADediting_1344248	ENST00000527278.5	chr7_64897934_+	1075	-825.00	-820.40	-857.80
ADediting_1344249	ENST00000527278.5	chr7_64897938_+	1079	-822.00	-820.40	-857.80
ADediting_1344250	ENST00000527278.5	chr7_64897989_+	1130	-823.00	-820.40	-857.80
ADediting_1344251	ENST00000527278.5	chr7_64898001_+	1142	-820.70	-820.40	-857.80
ADediting_1344395	ENST00000489672.5	chr7_64923421_+	462	-382.07	-381.17	-394.77
ADediting_1344396	ENST00000489672.5	chr7_64923441_+	482	-382.47	-381.17	-394.77
ADediting_1344397	ENST00000489672.5	chr7_64923442_+	483	-383.67	-381.17	-394.77
ADediting_1344398	ENST00000489672.5	chr7_64923525_+	566	-381.57	-381.17	-394.77
ADediting_1344399	ENST00000489672.5	chr7_64923571_+	612	-388.37	-381.17	-394.77

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Relation with ADAR for ZNF273

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
CER	ADediting_1344245	chr7_64897912_+	3.6130485438597e-05	0.330524411860147	9.67298159237745e-06	0.352529750058381	0.00726520407174702	0.218358576521354
DLPFC	ADediting_1344246	chr7_64897918_+	1.12774263473197e-09	0.337085805163452	3.81184619122515e-12	0.380959563333596	0.00406340133446486	0.162754705675067
CER	ADediting_1344246	chr7_64897918_+	2.75423010678788e-06	0.372078949528947	3.36882680292838e-08	0.432081267539877	0.00654009380734047	0.221132072466936
TCX	ADediting_1344246	chr7_64897918_+	0.00532217781358196	0.226476242980092	1.26149294766264e-05	0.348226823032992	0.64853539990848	-0.0375164690481387
DLPFC	ADediting_1344248	chr7_64897934_+	0.000113861208721105	0.217426003222204	1.6022796642413e-11	0.370501716284264	0.0183533736107963	0.133885990486629
CER	ADediting_1344248	chr7_64897934_+	1.79606762099327e-05	0.34240224817651	9.76910500906382e-08	0.418614985495104	0.000162407442363664	0.303180852992424
TCX	ADediting_1344248	chr7_64897934_+	0.014367946731755	0.199527777797846	3.55860471195103e-05	0.33078768195914	0.295297722591908	-0.0860131838587257
CER	ADediting_1344249	chr7_64897938_+	3.83119857923815e-05	0.32950561169544	6.40076797539812e-06	0.359098560553517	0.0303551224543134	0.176889326112353
DLPFC	ADediting_1344331	chr7_64902641_+	0.429053119181622	0.04507441718514	0.263174562129145	-0.063743205475025	7.48950147025349e-13	0.392376852822597
DLPFC	ADediting_1344332	chr7_64902650_+	0.378414881528223	0.0501984957172125	0.460469387811131	-0.0420711887545332	4.67969533823324e-11	0.362442833470162
DLPFC	ADediting_1344334	chr7_64904144_+	0.0802516222131564	0.0995047473952104	0.640614612425952	-0.0266175397684866	4.48611592700105e-12	0.37979197269613
DLPFC	ADediting_1344336	chr7_64904192_+	0.258946036258361	0.0643098074945868	0.124994132781735	-0.0873197890730507	4.75775006844828e-20	0.489101952774117
DLPFC	ADediting_1344341	chr7_64904358_+	0.492418155204782	0.0391318986930465	0.0919412955526754	-0.0958821901991631	1.26527193407383e-20	0.495653386821951
DLPFC	ADediting_1344358	chr7_64916085_+	0.871257680202918	-0.00924159344523168	0.214528086789807	-0.0706933603059548	2.53499937370033e-09	0.330249930505225

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	1.24389406112525e-20	0.495736763930749	4.69699083751647e-11	0.36241470379497	5.68822792505452e-33	0.609921969929442
AC	1.04436143389696e-23	0.578255808673263	2.56609062431009e-20	0.539915871715534	3.25014690471279e-11	0.403651978846615
PCC	8.95149638314919e-21	0.609038620519662	7.53793223174064e-23	0.633791838571948	4.28736485650246e-10	0.432192722467066
CER	6.8824563437177e-24	0.705459284475437	5.50958816456916e-28	0.746633060804359	0.0110110048659584	0.207059415302563
TCX	8.45501059334543e-16	0.596087525574514	5.80164201069961e-34	0.795150889461573	0.83983263233983	0.016640073206911
FP	4.02882704607548e-26	0.686277139183949	4.22179133863697e-24	0.665170148104598	2.99391015536924e-06	0.341922017516775
IFG	6.2047787857376e-05	0.713590451568432	5.3737509001548e-06	0.775087455449892	0.00865383661134135	0.513506706392507
PG	1.73324006567352e-40	0.787235523251818	5.64367254611128e-41	0.790148388814269	0.949070783419705	0.00471520857085365
STG	1.16887208269627e-10	0.631712658042941	1.46495508800961e-09	0.601299025062292	0.0376388082336377	0.227240581300318

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Relation with AD stages for ZNF273

Correlation between AD stages and RNA editing frequency

Tissue	ADeditomID	position	P-val	Coeff.
CER	ADediting_1344236	chr7_64897511_+	0.000158038926409455	0.355719937073611

Correlation between AD stages and this gene's expression

Tissue	P-val	Coeff.
CER	1.20313698386988e-05	0.407490590575042

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RelatedDrugs for ZNF273

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for ZNF273

Diseases associated with this gene.
(DisGeNet 4.0)

Gene

Disease ID

Disease name

# pubmeds

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Gene summary for ZNF273

RNA A-to-I events for ZNF273

RNA editing positional annotations for ZNF273 using Annovar

RNA A-to-I editing events in the alternative splicing sites for ZNF273

Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF273

Protein coding region RNA A-to-I editings for ZNF273

The effects of the RNA editing to the miRNA binding sites for ZNF273

The effects of the RNA editing to the stability of the RNA structures for ZNF273

Relation with ADAR for ZNF273

Relation with AD stages for ZNF273

RelatedDrugs for ZNF273

RelatedDiseases for ZNF273

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene