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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for TCFL5

check button Gene summary
Gene informationGene symbol

TCFL5

Gene ID

10732

Gene nametranscription factor like 5
SynonymsCHA|E2BP-1|Figlb|SOSF1|bHLHe82
Cytomap

20q13.33

Type of geneprotein-coding
Descriptiontranscription factor-like 5 proteinHPV-16 E2-binding protein 1cha transcription factorspermatogenesis- and oogenesis-specific bHLH-containing protein 1transcription factor-like 5 (basic helix-loop-helix)
Modification date20200313
UniProtAcc

Q9UL49,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
TCFL5

GO:0000122

negative regulation of transcription by RNA polymerase II

12923186

TCFL5

GO:0006355

regulation of transcription, DNA-templated

9763657


Top

RNA A-to-I events for TCFL5

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_948254(62845207, -), ADediting_948255(62845254, -), ADediting_948256(62845259, -), ADediting_948257(62845260, -), ADediting_948258(62845350, -), ADediting_948259(62845365, -), ADediting_948260(62845378, -), ADediting_948261(62845395, -), ADediting_948262(62845409, -), ADediting_948263(62847123, -), ADediting_948264(62847144, -), ADediting_948265(62847825, -), ADediting_948266(62848566, -), ADediting_948267(62848699, -), ADediting_948268(62848932, -), ADediting_948269(62848950, -), ADediting_948270(62848965, -), ADediting_948271(62849005, -), ADediting_948272(62849046, -), ADediting_948273(62849052, -), ADediting_948274(62849113, -), ADediting_948275(62849806, -), ADediting_948276(62851845, -), ADediting_948277(62851870, -), ADediting_948278(62851873, -), ADediting_948279(62851877, -), ADediting_948280(62851878, -), ADediting_948281(62851882, -), ADediting_948282(62851885, -), ADediting_948283(62851886, -), ADediting_948284(62851906, -), ADediting_948285(62851914, -), ADediting_948286(62851920, -), ADediting_948287(62851923, -), ADediting_948288(62851937, -), ADediting_948289(62851941, -), ADediting_948290(62851947, -), ADediting_948291(62851965, -), ADediting_948292(62851969, -), ADediting_948293(62851973, -), ADediting_948294(62851974, -), ADediting_948295(62851975, -), ADediting_948296(62851978, -), ADediting_948297(62851980, -), ADediting_948298(62851981, -), ADediting_948299(62851982, -), ADediting_948300(62851983, -), ADediting_948301(62851984, -), ADediting_948302(62851987, -), ADediting_948303(62852004, -), ADediting_948304(62852007, -), ADediting_948305(62852009, -), ADediting_948306(62852010, -), ADediting_948307(62852033, -), ADediting_948308(62852094, -), ADediting_948309(62853382, -), ADediting_948310(62853385, -), ADediting_948311(62853407, -), ADediting_948312(62853409, -), ADediting_948313(62853423, -), ADediting_948314(62853488, -), ADediting_948315(62853496, -), ADediting_948316(62853514, -), ADediting_948317(62853517, -), ADediting_948318(62853519, -), ADediting_948319(62853520, -), ADediting_948320(62853526, -), ADediting_948321(62853530, -), ADediting_948322(62853539, -), ADediting_948323(62853546, -), ADediting_948324(62853547, -), ADediting_948325(62853552, -), ADediting_948326(62853554, -), ADediting_948327(62853555, -), ADediting_948328(62853564, -), ADediting_948329(62853600, -), ADediting_948330(62853623, -), ADediting_948331(62853624, -), ADediting_948332(62853640, -), ADediting_948333(62853646, -), ADediting_948334(62855193, -), ADediting_948335(62855194, -), ADediting_948336(62855222, -), ADediting_948337(62855262, -), ADediting_948338(62855268, -), ADediting_948339(62855277, -), ADediting_948340(62855290, -), ADediting_948341(62855294, -), ADediting_948342(62855306, -), ADediting_948343(62855322, -), ADediting_948344(62855358, -), ADediting_948345(62855362, -), ADediting_948346(62855379, -), ADediting_948347(62855380, -), ADediting_948348(62855390, -), ADediting_948349(62855510, -), ADediting_948350(62855519, -), ADediting_948351(62855550, -), ADediting_948352(62855562, -), ADediting_948353(62855575, -), ADediting_948354(62855638, -), ADediting_948355(62855654, -), ADediting_948356(62855666, -), ADediting_948357(62855683, -), ADediting_948358(62855684, -), ADediting_948359(62855690, -), ADediting_948360(62855703, -), ADediting_948361(62855708, -), ADediting_948362(62855727, -), ADediting_948363(62855740, -), ADediting_948364(62855753, -), ADediting_948365(62855994, -), ADediting_948366(62856006, -), ADediting_948367(62856044, -), ADediting_948368(62856057, -), ADediting_948369(62856064, -), ADediting_948370(62856066, -), ADediting_948371(62856069, -), ADediting_948372(62856076, -), ADediting_948373(62856083, -), ADediting_948374(62856086, -), ADediting_948375(62856101, -), ADediting_948376(62856102, -), ADediting_948377(62856106, -), ADediting_948378(62856126, -), ADediting_948379(62856128, -), ADediting_948380(62856138, -), ADediting_948381(62856150, -), ADediting_948382(62856174, -), ADediting_948383(62856187, -), ADediting_948384(62856203, -), ADediting_948385(62856206, -), ADediting_948386(62856251, -), ADediting_948387(62856515, -), ADediting_948388(62856540, -), ADediting_948389(62856557, -), ADediting_948390(62856558, -), ADediting_948391(62856582, -), ADediting_948392(62856584, -), ADediting_948393(62856594, -), ADediting_948394(62856606, -), ADediting_948395(62856624, -), ADediting_948396(62856659, -), ADediting_948397(62859853, -), ADediting_948398(62859858, -), ADediting_948399(62859885, -), ADediting_948400(62859927, -), ADediting_948401(62859928, -), ADediting_948402(62859981, -), ADediting_948403(62859982, -), ADediting_1567851(62848572, -), ADediting_1567852(62849847, -), ADediting_1567853(62853533, -), ADediting_1567854(62853575, -), ADediting_1567855(62853618, -), ADediting_1567856(62855387, -), ADediting_1567857(62855679, -), ADediting_1567858(62856547, -),

Top

RNA editing positional annotations for TCFL5 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_948254chr20_62845207_-UTR3
ADediting_948255chr20_62845254_-UTR3
ADediting_948256chr20_62845259_-UTR3
ADediting_948257chr20_62845260_-UTR3
ADediting_948258chr20_62845350_-UTR3
ADediting_948259chr20_62845365_-UTR3
ADediting_948260chr20_62845378_-UTR3
ADediting_948261chr20_62845395_-UTR3
ADediting_948262chr20_62845409_-UTR3
ADediting_948263chr20_62847123_-intronic
ADediting_948264chr20_62847144_-intronic
ADediting_948265chr20_62847825_-intronic
ADediting_948266chr20_62848566_-intronic
ADediting_948267chr20_62848699_-intronic
ADediting_948268chr20_62848932_-intronic
ADediting_948269chr20_62848950_-intronic
ADediting_948270chr20_62848965_-intronic
ADediting_948271chr20_62849005_-intronic
ADediting_948272chr20_62849046_-intronic
ADediting_948273chr20_62849052_-intronic
ADediting_948274chr20_62849113_-intronic
ADediting_948275chr20_62849806_-intronic
ADediting_948276chr20_62851845_-intronic
ADediting_948277chr20_62851870_-intronic
ADediting_948278chr20_62851873_-intronic
ADediting_948279chr20_62851877_-intronic
ADediting_948280chr20_62851878_-intronic
ADediting_948281chr20_62851882_-intronic
ADediting_948282chr20_62851885_-intronic
ADediting_948283chr20_62851886_-intronic
ADediting_948284chr20_62851906_-intronic
ADediting_948285chr20_62851914_-intronic
ADediting_948286chr20_62851920_-intronic
ADediting_948287chr20_62851923_-intronic
ADediting_948288chr20_62851937_-intronic
ADediting_948289chr20_62851941_-intronic
ADediting_948290chr20_62851947_-intronic
ADediting_948291chr20_62851965_-intronic
ADediting_948292chr20_62851969_-intronic
ADediting_948293chr20_62851973_-intronic
ADediting_948294chr20_62851974_-intronic
ADediting_948295chr20_62851975_-intronic
ADediting_948296chr20_62851978_-intronic
ADediting_948297chr20_62851980_-intronic
ADediting_948298chr20_62851981_-intronic
ADediting_948299chr20_62851982_-intronic
ADediting_948300chr20_62851983_-intronic
ADediting_948301chr20_62851984_-intronic
ADediting_948302chr20_62851987_-intronic
ADediting_948303chr20_62852004_-intronic
ADediting_948304chr20_62852007_-intronic
ADediting_948305chr20_62852009_-intronic
ADediting_948306chr20_62852010_-intronic
ADediting_948307chr20_62852033_-intronic
ADediting_948308chr20_62852094_-intronic
ADediting_948309chr20_62853382_-intronic
ADediting_948310chr20_62853385_-intronic
ADediting_948311chr20_62853407_-intronic
ADediting_948312chr20_62853409_-intronic
ADediting_948313chr20_62853423_-intronic
ADediting_948314chr20_62853488_-intronic
ADediting_948315chr20_62853496_-intronic
ADediting_948316chr20_62853514_-intronic
ADediting_948317chr20_62853517_-intronic
ADediting_948318chr20_62853519_-intronic
ADediting_948319chr20_62853520_-intronic
ADediting_948320chr20_62853526_-intronic
ADediting_948321chr20_62853530_-intronic
ADediting_948322chr20_62853539_-intronic
ADediting_948323chr20_62853546_-intronic
ADediting_948324chr20_62853547_-intronic
ADediting_948325chr20_62853552_-intronic
ADediting_948326chr20_62853554_-intronic
ADediting_948327chr20_62853555_-intronic
ADediting_948328chr20_62853564_-intronic
ADediting_948329chr20_62853600_-intronic
ADediting_948330chr20_62853623_-intronic
ADediting_948331chr20_62853624_-intronic
ADediting_948332chr20_62853640_-intronic
ADediting_948333chr20_62853646_-intronic
ADediting_948334chr20_62855193_-intronic
ADediting_948335chr20_62855194_-intronic
ADediting_948336chr20_62855222_-intronic
ADediting_948337chr20_62855262_-intronic
ADediting_948338chr20_62855268_-intronic
ADediting_948339chr20_62855277_-intronic
ADediting_948340chr20_62855290_-intronic
ADediting_948341chr20_62855294_-intronic
ADediting_948342chr20_62855306_-intronic
ADediting_948343chr20_62855322_-intronic
ADediting_948344chr20_62855358_-intronic
ADediting_948345chr20_62855362_-intronic
ADediting_948346chr20_62855379_-intronic
ADediting_948347chr20_62855380_-intronic
ADediting_948348chr20_62855390_-intronic
ADediting_948349chr20_62855510_-intronic
ADediting_948350chr20_62855519_-intronic
ADediting_948351chr20_62855550_-intronic
ADediting_948352chr20_62855562_-intronic
ADediting_948353chr20_62855575_-intronic
ADediting_948354chr20_62855638_-intronic
ADediting_948355chr20_62855654_-intronic
ADediting_948356chr20_62855666_-intronic
ADediting_948357chr20_62855683_-intronic
ADediting_948358chr20_62855684_-intronic
ADediting_948359chr20_62855690_-intronic
ADediting_948360chr20_62855703_-intronic
ADediting_948361chr20_62855708_-intronic
ADediting_948362chr20_62855727_-intronic
ADediting_948363chr20_62855740_-intronic
ADediting_948364chr20_62855753_-intronic
ADediting_948365chr20_62855994_-intronic
ADediting_948366chr20_62856006_-intronic
ADediting_948367chr20_62856044_-intronic
ADediting_948368chr20_62856057_-intronic
ADediting_948369chr20_62856064_-intronic
ADediting_948370chr20_62856066_-intronic
ADediting_948371chr20_62856069_-intronic
ADediting_948372chr20_62856076_-intronic
ADediting_948373chr20_62856083_-intronic
ADediting_948374chr20_62856086_-intronic
ADediting_948375chr20_62856101_-intronic
ADediting_948376chr20_62856102_-intronic
ADediting_948377chr20_62856106_-intronic
ADediting_948378chr20_62856126_-intronic
ADediting_948379chr20_62856128_-intronic
ADediting_948380chr20_62856138_-intronic
ADediting_948381chr20_62856150_-intronic
ADediting_948382chr20_62856174_-intronic
ADediting_948383chr20_62856187_-intronic
ADediting_948384chr20_62856203_-intronic
ADediting_948385chr20_62856206_-intronic
ADediting_948386chr20_62856251_-intronic
ADediting_948387chr20_62856515_-intronic
ADediting_948388chr20_62856540_-intronic
ADediting_948389chr20_62856557_-intronic
ADediting_948390chr20_62856558_-intronic
ADediting_948391chr20_62856582_-intronic
ADediting_948392chr20_62856584_-intronic
ADediting_948393chr20_62856594_-intronic
ADediting_948394chr20_62856606_-intronic
ADediting_948395chr20_62856624_-intronic
ADediting_948396chr20_62856659_-intronic
ADediting_948397chr20_62859853_-intronic
ADediting_948398chr20_62859858_-intronic
ADediting_948399chr20_62859885_-intronic
ADediting_948400chr20_62859927_-intronic
ADediting_948401chr20_62859928_-intronic
ADediting_948402chr20_62859981_-intronic
ADediting_948403chr20_62859982_-intronic
ADediting_1567851chr20_62848572_-intronic
ADediting_1567852chr20_62849847_-intronic
ADediting_1567853chr20_62853533_-intronic
ADediting_1567854chr20_62853575_-intronic
ADediting_1567855chr20_62853618_-intronic
ADediting_1567856chr20_62855387_-intronic
ADediting_1567857chr20_62855679_-intronic
ADediting_1567858chr20_62856547_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_948254chr20_62845207_-SINEAluName=AluSq2
ADediting_948255chr20_62845254_-SINEAluName=AluSq2
ADediting_948256chr20_62845259_-SINEAluName=AluSq2
ADediting_948257chr20_62845260_-SINEAluName=AluSq2
ADediting_948258chr20_62845350_-SINEAluName=AluSq2
ADediting_948259chr20_62845365_-SINEAluName=AluSq2
ADediting_948260chr20_62845378_-SINEAluName=AluSq2
ADediting_948261chr20_62845395_-SINEAluName=AluSq2
ADediting_948262chr20_62845409_-SINEAluName=AluSq2
ADediting_948263chr20_62847123_-SINEAluName=AluSp
ADediting_948264chr20_62847144_-SINEAluName=AluSp
ADediting_948265chr20_62847825_-SINEAluName=AluSx
ADediting_948266chr20_62848566_-SINEAluName=AluSq2
ADediting_948267chr20_62848699_-SINEAluName=AluSq2
ADediting_948268chr20_62848932_-SINEAluName=AluSz
ADediting_948269chr20_62848950_-SINEAluName=AluSz
ADediting_948270chr20_62848965_-SINEAluName=AluSz
ADediting_948271chr20_62849005_-SINEAluName=AluSz
ADediting_948272chr20_62849046_-SINEAluName=AluSz
ADediting_948273chr20_62849052_-SINEAluName=AluSz
ADediting_948274chr20_62849113_-SINEAluName=AluSz
ADediting_948275chr20_62849806_-SINEAluName=AluJb
ADediting_948276chr20_62851845_-SINEAluName=AluSz
ADediting_948277chr20_62851870_-SINEAluName=AluSz
ADediting_948278chr20_62851873_-SINEAluName=AluSz
ADediting_948279chr20_62851877_-SINEAluName=AluSz
ADediting_948280chr20_62851878_-SINEAluName=AluSz
ADediting_948281chr20_62851882_-SINEAluName=AluSz
ADediting_948282chr20_62851885_-SINEAluName=AluSz
ADediting_948283chr20_62851886_-SINEAluName=AluSz
ADediting_948284chr20_62851906_-SINEAluName=AluSz
ADediting_948285chr20_62851914_-SINEAluName=AluSz
ADediting_948286chr20_62851920_-SINEAluName=AluSz
ADediting_948287chr20_62851923_-SINEAluName=AluSz
ADediting_948288chr20_62851937_-SINEAluName=AluSz
ADediting_948289chr20_62851941_-SINEAluName=AluSz
ADediting_948290chr20_62851947_-SINEAluName=AluSz
ADediting_948291chr20_62851965_-SINEAluName=AluSz
ADediting_948292chr20_62851969_-SINEAluName=AluSz
ADediting_948293chr20_62851973_-SINEAluName=AluSz
ADediting_948294chr20_62851974_-SINEAluName=AluSz
ADediting_948295chr20_62851975_-SINEAluName=AluSz
ADediting_948296chr20_62851978_-SINEAluName=AluSz
ADediting_948297chr20_62851980_-SINEAluName=AluSz
ADediting_948298chr20_62851981_-SINEAluName=AluSz
ADediting_948299chr20_62851982_-SINEAluName=AluSz
ADediting_948300chr20_62851983_-SINEAluName=AluSz
ADediting_948301chr20_62851984_-SINEAluName=AluSz
ADediting_948302chr20_62851987_-SINEAluName=AluSz
ADediting_948303chr20_62852004_-SINEAluName=AluSz
ADediting_948304chr20_62852007_-SINEAluName=AluSz
ADediting_948305chr20_62852009_-SINEAluName=AluSz
ADediting_948306chr20_62852010_-SINEAluName=AluSz
ADediting_948307chr20_62852033_-SINEAluName=AluSz
ADediting_948308chr20_62852094_-SINEAluName=AluSz
ADediting_948309chr20_62853382_-SINEAluName=AluJb
ADediting_948310chr20_62853385_-SINEAluName=AluJb
ADediting_948311chr20_62853407_-SINEAluName=AluJb
ADediting_948312chr20_62853409_-SINEAluName=AluJb
ADediting_948313chr20_62853423_-SINEAluName=AluJb
ADediting_948314chr20_62853488_-SINEAluName=AluJb
ADediting_948315chr20_62853496_-SINEAluName=AluJb
ADediting_948316chr20_62853514_-SINEAluName=AluJb
ADediting_948317chr20_62853517_-SINEAluName=AluJb
ADediting_948318chr20_62853519_-SINEAluName=AluJb
ADediting_948319chr20_62853520_-SINEAluName=AluJb
ADediting_948320chr20_62853526_-SINEAluName=AluJb
ADediting_948321chr20_62853530_-SINEAluName=AluJb
ADediting_948322chr20_62853539_-SINEAluName=AluJb
ADediting_948323chr20_62853546_-SINEAluName=AluJb
ADediting_948324chr20_62853547_-SINEAluName=AluJb
ADediting_948325chr20_62853552_-SINEAluName=AluJb
ADediting_948326chr20_62853554_-SINEAluName=AluJb
ADediting_948327chr20_62853555_-SINEAluName=AluJb
ADediting_948328chr20_62853564_-SINEAluName=AluJb
ADediting_948329chr20_62853600_-SINEAluName=AluJb
ADediting_948330chr20_62853623_-SINEAluName=AluJb
ADediting_948331chr20_62853624_-SINEAluName=AluJb
ADediting_948332chr20_62853640_-SINEAluName=AluJb
ADediting_948333chr20_62853646_-SINEAluName=AluJb
ADediting_948334chr20_62855193_-SINEAluName=AluJo
ADediting_948335chr20_62855194_-SINEAluName=AluJo
ADediting_948336chr20_62855222_-SINEAluName=AluJo
ADediting_948337chr20_62855262_-SINEAluName=AluJo
ADediting_948338chr20_62855268_-SINEAluName=AluJo
ADediting_948339chr20_62855277_-SINEAluName=AluJo
ADediting_948340chr20_62855290_-SINEAluName=AluJo
ADediting_948341chr20_62855294_-SINEAluName=AluJo
ADediting_948342chr20_62855306_-SINEAluName=AluJo
ADediting_948343chr20_62855322_-SINEAluName=AluJo
ADediting_948344chr20_62855358_-SINEAluName=AluJo
ADediting_948345chr20_62855362_-SINEAluName=AluJo
ADediting_948346chr20_62855379_-SINEAluName=AluJo
ADediting_948347chr20_62855380_-SINEAluName=AluJo
ADediting_948348chr20_62855390_-SINEAluName=AluJo
ADediting_948349chr20_62855510_-SINEAluName=AluSp
ADediting_948350chr20_62855519_-SINEAluName=AluSp
ADediting_948351chr20_62855550_-SINEAluName=AluSp
ADediting_948352chr20_62855562_-SINEAluName=AluSp
ADediting_948353chr20_62855575_-SINEAluName=AluSp
ADediting_948354chr20_62855638_-SINEAluName=AluSp
ADediting_948355chr20_62855654_-SINEAluName=AluSp
ADediting_948356chr20_62855666_-SINEAluName=AluSp
ADediting_948357chr20_62855683_-SINEAluName=AluSp
ADediting_948358chr20_62855684_-SINEAluName=AluSp
ADediting_948359chr20_62855690_-SINEAluName=AluSp
ADediting_948360chr20_62855703_-SINEAluName=AluSp
ADediting_948361chr20_62855708_-SINEAluName=AluSp
ADediting_948362chr20_62855727_-SINEAluName=AluSp
ADediting_948363chr20_62855740_-SINEAluName=AluSp
ADediting_948364chr20_62855753_-SINEAluName=AluSp
ADediting_948365chr20_62855994_-SINEAluName=AluSx4
ADediting_948366chr20_62856006_-SINEAluName=AluSx4
ADediting_948367chr20_62856044_-SINEAluName=AluSx4
ADediting_948368chr20_62856057_-SINEAluName=AluSx4
ADediting_948369chr20_62856064_-SINEAluName=AluSx4
ADediting_948370chr20_62856066_-SINEAluName=AluSx4
ADediting_948371chr20_62856069_-SINEAluName=AluSx4
ADediting_948372chr20_62856076_-SINEAluName=AluSx4
ADediting_948373chr20_62856083_-SINEAluName=AluSx4
ADediting_948374chr20_62856086_-SINEAluName=AluSx4
ADediting_948375chr20_62856101_-SINEAluName=AluSx4
ADediting_948376chr20_62856102_-SINEAluName=AluSx4
ADediting_948377chr20_62856106_-SINEAluName=AluSx4
ADediting_948378chr20_62856126_-SINEAluName=AluSx4
ADediting_948379chr20_62856128_-SINEAluName=AluSx4
ADediting_948380chr20_62856138_-SINEAluName=AluSx4
ADediting_948381chr20_62856150_-SINEAluName=AluSx4
ADediting_948382chr20_62856174_-SINEAluName=AluSx4
ADediting_948383chr20_62856187_-SINEAluName=AluSx4
ADediting_948384chr20_62856203_-SINEAluName=AluSx4
ADediting_948385chr20_62856206_-SINEAluName=AluSx4
ADediting_948386chr20_62856251_-SINEAluName=AluSx4
ADediting_948387chr20_62856515_-SINEAluName=AluY
ADediting_948388chr20_62856540_-SINEAluName=AluY
ADediting_948389chr20_62856557_-SINEAluName=AluY
ADediting_948390chr20_62856558_-SINEAluName=AluY
ADediting_948391chr20_62856582_-SINEAluName=AluY
ADediting_948392chr20_62856584_-SINEAluName=AluY
ADediting_948393chr20_62856594_-SINEAluName=AluY
ADediting_948394chr20_62856606_-SINEAluName=AluY
ADediting_948395chr20_62856624_-SINEAluName=AluY
ADediting_948396chr20_62856659_-SINEAluName=AluY
ADediting_948397chr20_62859853_-SINEAluName=AluSx1
ADediting_948398chr20_62859858_-SINEAluName=AluSx1
ADediting_948399chr20_62859885_-SINEAluName=AluSx1
ADediting_948400chr20_62859927_-SINEAluName=AluSx1
ADediting_948401chr20_62859928_-SINEAluName=AluSx1
ADediting_948402chr20_62859981_-SINEAluName=AluSx1
ADediting_948403chr20_62859982_-SINEAluName=AluSx1
ADediting_1567851chr20_62848572_-SINEAluName=AluSq2
ADediting_1567852chr20_62849847_-SINEAluName=AluJb
ADediting_1567853chr20_62853533_-SINEAluName=AluJb
ADediting_1567854chr20_62853575_-SINEAluName=AluJb
ADediting_1567855chr20_62853618_-SINEAluName=AluJb
ADediting_1567856chr20_62855387_-SINEAluName=AluJo
ADediting_1567857chr20_62855679_-SINEAluName=AluSp
ADediting_1567858chr20_62856547_-SINEAluName=AluY

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RNA A-to-I editing events in the alternative splicing sites for TCFL5

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESADediting_948386chr20_62856251_-62856247:628562693ss2iTTTTTTTTTTTTTTTTTGAGACG3.97TTTTTTTTTTTTTTTTTGGGACG-3.99
ESADediting_948386chr20_62856251_-62856247:628562693ss2iTTTTTTTTTTTTTTTTTGAGACG3.97TTTTTTTTTTTTTTTTTGGGACG-3.99
ESADediting_948386chr20_62856251_-62856247:628562693ss2iTTTTTTTTTTTTTTTTTGAGACG3.97TTTTTTTTTTTTTTTTTGGGACG-3.99
ESADediting_948378chr20_62856126_-62856119:628561275ss2eCAGGTACCC8.63CGGGTACCC4.19
ESADediting_948378chr20_62856126_-62856119:628561275ss2eCAGGTACCC8.63CGGGTACCC4.19
ESADediting_948378chr20_62856126_-62856119:628561275ss2eCAGGTACCC8.63CGGGTACCC4.19
ESADediting_948378chr20_62856126_-62856119:628561275ss2eCAGGTACCC8.63CGGGTACCC4.19
ESADediting_948378chr20_62856126_-62856119:628561275ss2eCAGGTACCC8.63CGGGTACCC4.19
ME1ADediting_948386chr20_62856251_-62856247:628562693ss2iTTTTTTTTTTTTTTTTTGAGACG3.97TTTTTTTTTTTTTTTTTGGGACG-3.99

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TCFL5

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for TCFL5

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for TCFL5

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_948254chr20_62845207_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-1281chr2062845206628452138mer-1a6284520662845222145-18.19
ADediting_948256chr20_62845259_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-8052chr2062845254628452607mer-1a6284525462845272143-23.67
ADediting_948257chr20_62845260_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-513a-5pchr2062845259628452657mer-m86284525862845275156-19.07
ADediting_948257chr20_62845260_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-638chr2062845254628452607mer-1a6284525462845278159-34.39
ADediting_948260chr20_62845378_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-150-5pchr2062845378628453847mer-m86284537762845398140-15.8
ADediting_948260chr20_62845378_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-6778-3pchr2062845376628453827mer-m86284537562845395143-14.47
ADediting_948261chr20_62845395_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-8052chr2062845390628453967mer-1a6284539062845408140-24.15
ADediting_948262chr20_62845409_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-6807-5pchr2062845404628454107mer-m86284540362845424140-18.6

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_948254chr20_62845207_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-3152-5pchr2062845205628452128mer-1a6284520562845228150-16.15
ADediting_948254chr20_62845207_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-6782-3pchr2062845202628452087mer-m86284520162845223153-17.36
ADediting_948254chr20_62845207_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-6836-3pchr2062845206628452138mer-1a6284520662845226140-14.97
ADediting_948255chr20_62845254_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-5089-5pchr2062845254628452607mer-m86284525362845276149-15.84
ADediting_948255chr20_62845254_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-6506-5pchr2062845253628452597mer-m86284525262845273147-16.08
ADediting_948256chr20_62845259_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-10399-5pchr2062845258628452647mer-m86284525762845278152-11.75
ADediting_948256chr20_62845259_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-5089-5pchr2062845254628452607mer-m86284525362845276149-15.84
ADediting_948256chr20_62845259_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-6504-3pchr2062845258628452647mer-m86284525762845278144-12.42
ADediting_948257chr20_62845260_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-10399-5pchr2062845258628452647mer-m86284525762845278152-11.75
ADediting_948257chr20_62845260_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-6504-3pchr2062845258628452647mer-m86284525762845278144-12.42
ADediting_948257chr20_62845260_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-7151-3pchr2062845259628452668mer-1a6284525962845280143-12.91
ADediting_948261chr20_62845395_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-10399-5pchr2062845394628454007mer-m86284539362845415141-10.39
ADediting_948261chr20_62845395_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-5089-5pchr2062845390628453967mer-m86284538962845411148-13.96
ADediting_948261chr20_62845395_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-6504-3pchr2062845394628454007mer-m86284539362845412140-7.96

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-589-3pchr2062845574628455807mer-1a6284557462845597140-31.77
ADediting_1337757chr7_5495852_-ENSG00000101190.13ENST00000335351.8TCFL5-202hsa-miR-589-3pchr2062841690628416978mer-1a6284169062841713140-15.72
ADediting_1556067chr19_40282625_-ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-641chr2062845721628457277mer-m86284572062845743145-17.61
ADediting_1631458chr19_40282624_-ENSG00000101190.13ENST00000335351.8TCFL5-202hsa-miR-641chr2062841775628417817mer-m86284177462841799150-15.56

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1535951chr14_100874558_+ENSG00000101190.13ENST00000217162.5TCFL5-201hsa-miR-337-3pchr2062845483628454908mer-1a6284548362845507155-15.17
ADediting_1596844chr1_162342605_+ENSG00000101190.13ENST00000335351.8TCFL5-202hsa-miR-556-3pchr2062841253628412597mer-m86284125262841272144-7.14

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for TCFL5

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000217162.5protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_948254ENST00000217162.5chr20_62845207_-2384-1026.80-1025.80-1037.30
ADediting_948255ENST00000217162.5chr20_62845254_-2337-1028.80-1025.80-1037.30
ADediting_948256ENST00000217162.5chr20_62845259_-2332-1026.60-1025.80-1037.30
ADediting_948257ENST00000217162.5chr20_62845260_-2331-1026.80-1025.80-1037.30
ADediting_948258ENST00000217162.5chr20_62845350_-2241-1026.90-1025.80-1037.30
ADediting_948259ENST00000217162.5chr20_62845365_-2226-1030.00-1025.80-1037.30
ADediting_948260ENST00000217162.5chr20_62845378_-2213-1031.30-1025.80-1037.30
ADediting_948261ENST00000217162.5chr20_62845395_-2196-1025.80-1025.80-1037.30
ADediting_948262ENST00000217162.5chr20_62845409_-2182-1026.00-1025.80-1037.30

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for TCFL5

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_948278chr20_62851873_-0.006816939763063010.2200423230401632.30897008641616e-050.3381891180897420.1611135717850590.115000671607412
DLPFCADediting_948320chr20_62853526_-0.3070717432802980.05819672930023640.491728520815739-0.03919423587164722.88890553372363e-130.398861931159023
CERADediting_948337chr20_62855262_-1.50258056406644e-050.3453580929859482.35776772786142e-080.4364667250607130.001697279423001250.254173783712045
CERADediting_948339chr20_62855277_-0.001102329876513610.2638928290668960.0007458856464791440.272386970543590.0001891649312945790.300251644738154
CERADediting_948340chr20_62855290_-0.0002147857352166780.2977881317547381.21214440388101e-080.444481030386170.04952719727976370.160662665536273
CERADediting_948348chr20_62855390_-0.004763643783866010.2293033012234877.05495235512777e-060.357563578335860.3372703225875360.0788865229732443
CERADediting_948356chr20_62855666_-0.0003227096933885230.2897404299878154.10441632328803e-050.3283038849302770.3486856812864320.0770480226117968
CERADediting_948362chr20_62855727_-0.02354561289863040.1848427521454174.86331570146723e-050.3253225637564610.347956920483040.0771642474144222
CERADediting_948363chr20_62855740_-0.0009284509680614640.2676596623555582.97636625380668e-050.3338677180341260.4907484500093850.0566953238222523
DLPFCADediting_948374chr20_62856086_-0.07537502710559330.1011430445536760.668924383237346-0.02438233818527213.50711760399003e-120.381555059960691

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.29899163724902e-230.5275903707155861.98310275337312e-190.4818799423634527.42603272228389e-100.340547594507525
AC8.60239860204743e-340.6688883471880323.53912570006314e-220.5615647966504557.79982338818386e-290.628036255110529
PCC4.82680071904619e-090.4076462279599185.55936825911229e-090.4061507028180180.0003001318717611860.258813319394529
CER0.0391098531266670.168647943930420.122045560785610.1268009108327662.06291823590452e-060.376401236101394
TCX0.901243588746531-0.01021715715732451.18791215404135e-06-0.3844869180675478.01462197662036e-110.499070451798524
FP1.73910677414429e-100.4551378089109633.30798032126361e-110.4708264432417393.76650845557241e-090.423773069874988
PG2.41370784051997e-300.7143844342528578.7606012090009e-160.5450496963084090.03351875616516770.155968481700604
STG7.47066461443877e-110.6367707362952338.07325701466225e-070.50808064053470.0003503006388622810.380949592632312

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Relation with AD stages for TCFL5

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
IFGADediting_948290chr20_62851947_-0.03009815802707530.434211849874622

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for TCFL5

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TCFL5

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource