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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for RN7SL737P |
 Gene summary |
| Gene information | Gene symbol | RN7SL737P | Gene ID | 106481123 |
| Gene name | RNA, 7SL, cytoplasmic 737, pseudogene | |
| Synonyms | - | |
| Cytomap | 12q22 | |
| Type of gene | pseudo | |
| Description | - | |
| Modification date | 20200320 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for RN7SL737P |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_376303(93509490, +), ADediting_376304(93509496, +), ADediting_376305(93509502, +), ADediting_376306(93509512, +), ADediting_376307(93509526, +), ADediting_376308(93509534, +), ADediting_376309(93509535, +), ADediting_376310(93509539, +), ADediting_376311(93509542, +), ADediting_376312(93509548, +), ADediting_376313(93509553, +), ADediting_376314(93509558, +), ADediting_376315(93509561, +), ADediting_376316(93509704, +), |
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RNA editing positional annotations for RN7SL737P using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_376303 | chr12_93509490_+ | ncRNA_exonic |
| ADediting_376304 | chr12_93509496_+ | ncRNA_exonic |
| ADediting_376305 | chr12_93509502_+ | ncRNA_exonic |
| ADediting_376306 | chr12_93509512_+ | ncRNA_exonic |
| ADediting_376307 | chr12_93509526_+ | ncRNA_exonic |
| ADediting_376308 | chr12_93509534_+ | ncRNA_exonic |
| ADediting_376309 | chr12_93509535_+ | ncRNA_exonic |
| ADediting_376310 | chr12_93509539_+ | ncRNA_exonic |
| ADediting_376311 | chr12_93509542_+ | ncRNA_exonic |
| ADediting_376312 | chr12_93509548_+ | ncRNA_exonic |
| ADediting_376313 | chr12_93509553_+ | ncRNA_exonic |
| ADediting_376314 | chr12_93509558_+ | ncRNA_exonic |
| ADediting_376315 | chr12_93509561_+ | ncRNA_exonic |
| ADediting_376316 | chr12_93509704_+ | ncRNA_exonic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_376303 | chr12_93509490_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376304 | chr12_93509496_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376305 | chr12_93509502_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376306 | chr12_93509512_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376307 | chr12_93509526_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376308 | chr12_93509534_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376309 | chr12_93509535_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376310 | chr12_93509539_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376311 | chr12_93509542_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376312 | chr12_93509548_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376313 | chr12_93509553_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376314 | chr12_93509558_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376315 | chr12_93509561_+ | srpRNA | srpRNA | Name=7SLRNA |
| ADediting_376316 | chr12_93509704_+ | srpRNA | srpRNA | Name=7SLRNA |
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RNA A-to-I editing events in the alternative splicing sites for RN7SL737P |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RN7SL737P |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for RN7SL737P |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for RN7SL737P |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for RN7SL737P |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for RN7SL737P |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 7.9071141788334e-11 | 0.358415333691821 | 1.45105532612642e-13 | 0.403463010270093 | 0.122543837339644 | 0.0878889956068323 |
| PCC | 1.57873634146419e-10 | 0.441774816601925 | 1.00753764330207e-10 | 0.44598696195799 | 0.418343045828859 | 0.058894587101978 |
| CER | 1.21563806223885e-23 | 0.702724790019939 | 1.10953312243868e-19 | 0.65419998450842 | 0.081289409947629 | 0.142800215353665 |
| TCX | 6.47114131424083e-16 | 0.598012337462993 | 1.18339439368952e-08 | 0.444766341860261 | 0.0369788608387773 | 0.170498117522635 |
| IFG | 0.0478581648080246 | -0.399522921377022 | 0.0954875982734861 | -0.340807342145954 | 0.853651994707719 | 0.0388682051771049 |
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Relation with AD stages for RN7SL737P |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 0.000506278256652892 | 0.329073237868716 |
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RelatedDrugs for RN7SL737P |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RN7SL737P |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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