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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for PCCA-DT

check button Gene summary
Gene informationGene symbol

PCCA-DT

Gene ID

105370333

Gene namePCCA divergent transcript
Synonyms-
Cytomap

13q32.3

Type of genencRNA
Description-
Modification date20200313
UniProtAcc

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for PCCA-DT

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_380346(100059486, -), ADediting_380347(100059595, -), ADediting_380348(100061076, -), ADediting_380349(100065428, -), ADediting_380350(100065566, -), ADediting_380351(100065580, -), ADediting_380352(100065605, -), ADediting_380353(100066767, -), ADediting_380354(100066789, -), ADediting_380355(100066792, -), ADediting_380356(100067708, -), ADediting_380357(100067723, -), ADediting_380358(100067877, -), ADediting_380359(100067890, -), ADediting_380360(100069915, -), ADediting_380361(100069927, -), ADediting_380362(100069937, -), ADediting_380363(100069977, -), ADediting_380364(100069997, -), ADediting_380365(100070067, -), ADediting_380366(100070078, -), ADediting_380367(100070083, -), ADediting_380368(100070090, -), ADediting_380369(100070091, -), ADediting_380370(100070122, -), ADediting_380371(100070127, -), ADediting_380372(100070128, -), ADediting_380373(100070132, -), ADediting_380374(100070141, -), ADediting_380375(100070168, -), ADediting_380376(100070169, -), ADediting_380377(100070500, -), ADediting_380378(100070506, -), ADediting_380379(100070516, -), ADediting_380380(100070524, -), ADediting_380381(100070529, -), ADediting_380382(100070532, -), ADediting_380383(100070577, -), ADediting_380384(100070590, -), ADediting_380385(100070594, -), ADediting_380386(100070596, -), ADediting_380387(100070602, -), ADediting_380388(100070605, -), ADediting_380389(100070624, -), ADediting_380390(100070634, -), ADediting_380391(100070653, -), ADediting_380392(100070657, -), ADediting_380393(100070664, -), ADediting_380394(100070673, -), ADediting_380395(100071180, -), ADediting_380396(100071183, -), ADediting_380397(100071195, -), ADediting_380398(100071196, -), ADediting_380399(100071222, -), ADediting_380400(100071223, -), ADediting_380401(100071236, -), ADediting_380402(100072840, -), ADediting_380403(100073047, -), ADediting_380404(100073053, -), ADediting_380405(100073059, -), ADediting_380406(100073778, -), ADediting_380407(100073781, -), ADediting_380408(100073794, -), ADediting_380409(100073813, -), ADediting_380410(100073817, -), ADediting_380411(100073836, -), ADediting_380412(100073839, -), ADediting_380413(100073845, -), ADediting_380414(100073860, -), ADediting_380415(100073908, -), ADediting_380416(100073936, -), ADediting_380417(100073948, -), ADediting_380418(100074692, -), ADediting_380419(100074696, -), ADediting_380420(100074765, -), ADediting_380421(100074955, -), ADediting_380422(100074960, -), ADediting_380423(100074961, -), ADediting_380424(100075004, -), ADediting_380425(100075007, -), ADediting_380426(100075093, -), ADediting_380427(100075111, -), ADediting_380428(100075163, -), ADediting_380429(100075164, -), ADediting_380430(100075391, -), ADediting_380431(100075400, -), ADediting_380432(100075413, -), ADediting_380433(100075430, -), ADediting_380434(100075463, -), ADediting_380435(100075465, -), ADediting_380436(100075475, -), ADediting_380437(100075481, -), ADediting_380438(100075490, -), ADediting_380439(100075499, -), ADediting_380440(100075535, -), ADediting_380441(100075538, -), ADediting_380442(100075539, -), ADediting_380443(100075547, -), ADediting_380444(100075552, -), ADediting_380445(100075564, -), ADediting_380446(100075565, -), ADediting_380447(100075595, -), ADediting_380448(100075603, -), ADediting_380449(100075614, -), ADediting_380450(100075625, -), ADediting_380451(100075641, -), ADediting_380452(100076467, -), ADediting_380453(100076479, -), ADediting_380454(100076489, -), ADediting_380455(100076519, -), ADediting_380456(100076534, -), ADediting_380457(100076550, -), ADediting_380458(100076556, -), ADediting_380459(100076559, -), ADediting_380460(100076601, -), ADediting_380461(100076654, -), ADediting_380462(100076660, -), ADediting_380463(100076721, -), ADediting_380464(100076984, -), ADediting_380465(100085305, -), ADediting_380466(100085314, -), ADediting_380467(100085315, -), ADediting_380468(100085333, -), ADediting_380469(100085337, -), ADediting_380470(100085341, -), ADediting_380471(100085449, -), ADediting_380472(100085516, -), ADediting_380473(100085555, -), ADediting_380474(100085701, -), ADediting_380475(100085730, -), ADediting_380476(100085731, -), ADediting_380477(100085734, -), ADediting_380478(100085755, -), ADediting_380479(100085809, -), ADediting_380480(100085819, -), ADediting_380481(100085820, -), ADediting_380482(100085843, -), ADediting_380483(100085854, -), ADediting_380484(100085947, -), ADediting_380485(100085956, -), ADediting_380486(100086479, -), ADediting_380487(100086515, -), ADediting_380488(100086527, -), ADediting_380489(100086530, -), ADediting_380490(100086534, -), ADediting_380491(100086556, -), ADediting_380492(100086575, -), ADediting_380493(100086595, -), ADediting_380494(100086598, -), ADediting_380495(100086601, -), ADediting_380496(100086622, -), ADediting_380497(100086690, -), ADediting_380498(100086692, -), ADediting_1534543(100069976, -), ADediting_1534544(100070051, -), ADediting_1534545(100070057, -), ADediting_1534546(100070070, -), ADediting_1534547(100070071, -), ADediting_1534548(100070136, -), ADediting_1534549(100070512, -), ADediting_1534550(100070644, -), ADediting_1534551(100070651, -), ADediting_1534552(100072871, -), ADediting_1534553(100072892, -), ADediting_1534554(100072933, -), ADediting_1534555(100072938, -), ADediting_1534556(100075525, -), ADediting_1534557(100075609, -), ADediting_1534558(100085723, -), ADediting_1534559(100085785, -), ADediting_1534560(100085936, -), ADediting_1534561(100086594, -),

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RNA editing positional annotations for PCCA-DT using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_380346chr13_100059486_-ncRNA_intronic
ADediting_380347chr13_100059595_-ncRNA_intronic
ADediting_380348chr13_100061076_-ncRNA_intronic
ADediting_380349chr13_100065428_-ncRNA_intronic
ADediting_380350chr13_100065566_-ncRNA_intronic
ADediting_380351chr13_100065580_-ncRNA_intronic
ADediting_380352chr13_100065605_-ncRNA_intronic
ADediting_380353chr13_100066767_-ncRNA_intronic
ADediting_380354chr13_100066789_-ncRNA_intronic
ADediting_380355chr13_100066792_-ncRNA_intronic
ADediting_380356chr13_100067708_-ncRNA_intronic
ADediting_380357chr13_100067723_-ncRNA_intronic
ADediting_380358chr13_100067877_-ncRNA_intronic
ADediting_380359chr13_100067890_-ncRNA_intronic
ADediting_380360chr13_100069915_-ncRNA_intronic
ADediting_380361chr13_100069927_-ncRNA_intronic
ADediting_380362chr13_100069937_-ncRNA_intronic
ADediting_380363chr13_100069977_-ncRNA_intronic
ADediting_380364chr13_100069997_-ncRNA_intronic
ADediting_380365chr13_100070067_-ncRNA_intronic
ADediting_380366chr13_100070078_-ncRNA_intronic
ADediting_380367chr13_100070083_-ncRNA_intronic
ADediting_380368chr13_100070090_-ncRNA_intronic
ADediting_380369chr13_100070091_-ncRNA_intronic
ADediting_380370chr13_100070122_-ncRNA_intronic
ADediting_380371chr13_100070127_-ncRNA_intronic
ADediting_380372chr13_100070128_-ncRNA_intronic
ADediting_380373chr13_100070132_-ncRNA_intronic
ADediting_380374chr13_100070141_-ncRNA_intronic
ADediting_380375chr13_100070168_-ncRNA_intronic
ADediting_380376chr13_100070169_-ncRNA_intronic
ADediting_380377chr13_100070500_-ncRNA_intronic
ADediting_380378chr13_100070506_-ncRNA_intronic
ADediting_380379chr13_100070516_-ncRNA_intronic
ADediting_380380chr13_100070524_-ncRNA_intronic
ADediting_380381chr13_100070529_-ncRNA_intronic
ADediting_380382chr13_100070532_-ncRNA_intronic
ADediting_380383chr13_100070577_-ncRNA_intronic
ADediting_380384chr13_100070590_-ncRNA_intronic
ADediting_380385chr13_100070594_-ncRNA_intronic
ADediting_380386chr13_100070596_-ncRNA_intronic
ADediting_380387chr13_100070602_-ncRNA_intronic
ADediting_380388chr13_100070605_-ncRNA_intronic
ADediting_380389chr13_100070624_-ncRNA_intronic
ADediting_380390chr13_100070634_-ncRNA_intronic
ADediting_380391chr13_100070653_-ncRNA_intronic
ADediting_380392chr13_100070657_-ncRNA_intronic
ADediting_380393chr13_100070664_-ncRNA_intronic
ADediting_380394chr13_100070673_-ncRNA_intronic
ADediting_380395chr13_100071180_-ncRNA_intronic
ADediting_380396chr13_100071183_-ncRNA_intronic
ADediting_380397chr13_100071195_-ncRNA_intronic
ADediting_380398chr13_100071196_-ncRNA_intronic
ADediting_380399chr13_100071222_-ncRNA_intronic
ADediting_380400chr13_100071223_-ncRNA_intronic
ADediting_380401chr13_100071236_-ncRNA_intronic
ADediting_380402chr13_100072840_-ncRNA_intronic
ADediting_380403chr13_100073047_-ncRNA_intronic
ADediting_380404chr13_100073053_-ncRNA_intronic
ADediting_380405chr13_100073059_-ncRNA_intronic
ADediting_380406chr13_100073778_-ncRNA_intronic
ADediting_380407chr13_100073781_-ncRNA_intronic
ADediting_380408chr13_100073794_-ncRNA_intronic
ADediting_380409chr13_100073813_-ncRNA_intronic
ADediting_380410chr13_100073817_-ncRNA_intronic
ADediting_380411chr13_100073836_-ncRNA_intronic
ADediting_380412chr13_100073839_-ncRNA_intronic
ADediting_380413chr13_100073845_-ncRNA_intronic
ADediting_380414chr13_100073860_-ncRNA_intronic
ADediting_380415chr13_100073908_-ncRNA_intronic
ADediting_380416chr13_100073936_-ncRNA_intronic
ADediting_380417chr13_100073948_-ncRNA_intronic
ADediting_380418chr13_100074692_-ncRNA_intronic
ADediting_380419chr13_100074696_-ncRNA_intronic
ADediting_380420chr13_100074765_-ncRNA_intronic
ADediting_380421chr13_100074955_-ncRNA_intronic
ADediting_380422chr13_100074960_-ncRNA_intronic
ADediting_380423chr13_100074961_-ncRNA_intronic
ADediting_380424chr13_100075004_-ncRNA_intronic
ADediting_380425chr13_100075007_-ncRNA_intronic
ADediting_380426chr13_100075093_-ncRNA_intronic
ADediting_380427chr13_100075111_-ncRNA_intronic
ADediting_380428chr13_100075163_-ncRNA_intronic
ADediting_380429chr13_100075164_-ncRNA_intronic
ADediting_380430chr13_100075391_-ncRNA_intronic
ADediting_380431chr13_100075400_-ncRNA_intronic
ADediting_380432chr13_100075413_-ncRNA_intronic
ADediting_380433chr13_100075430_-ncRNA_intronic
ADediting_380434chr13_100075463_-ncRNA_intronic
ADediting_380435chr13_100075465_-ncRNA_intronic
ADediting_380436chr13_100075475_-ncRNA_intronic
ADediting_380437chr13_100075481_-ncRNA_intronic
ADediting_380438chr13_100075490_-ncRNA_intronic
ADediting_380439chr13_100075499_-ncRNA_intronic
ADediting_380440chr13_100075535_-ncRNA_intronic
ADediting_380441chr13_100075538_-ncRNA_intronic
ADediting_380442chr13_100075539_-ncRNA_intronic
ADediting_380443chr13_100075547_-ncRNA_intronic
ADediting_380444chr13_100075552_-ncRNA_intronic
ADediting_380445chr13_100075564_-ncRNA_intronic
ADediting_380446chr13_100075565_-ncRNA_intronic
ADediting_380447chr13_100075595_-ncRNA_intronic
ADediting_380448chr13_100075603_-ncRNA_intronic
ADediting_380449chr13_100075614_-ncRNA_intronic
ADediting_380450chr13_100075625_-ncRNA_intronic
ADediting_380451chr13_100075641_-ncRNA_intronic
ADediting_380452chr13_100076467_-ncRNA_intronic
ADediting_380453chr13_100076479_-ncRNA_intronic
ADediting_380454chr13_100076489_-ncRNA_intronic
ADediting_380455chr13_100076519_-ncRNA_intronic
ADediting_380456chr13_100076534_-ncRNA_intronic
ADediting_380457chr13_100076550_-ncRNA_intronic
ADediting_380458chr13_100076556_-ncRNA_intronic
ADediting_380459chr13_100076559_-ncRNA_intronic
ADediting_380460chr13_100076601_-ncRNA_intronic
ADediting_380461chr13_100076654_-ncRNA_intronic
ADediting_380462chr13_100076660_-ncRNA_intronic
ADediting_380463chr13_100076721_-ncRNA_intronic
ADediting_380464chr13_100076984_-ncRNA_intronic
ADediting_380465chr13_100085305_-ncRNA_intronic
ADediting_380466chr13_100085314_-ncRNA_intronic
ADediting_380467chr13_100085315_-ncRNA_intronic
ADediting_380468chr13_100085333_-ncRNA_intronic
ADediting_380469chr13_100085337_-ncRNA_intronic
ADediting_380470chr13_100085341_-ncRNA_intronic
ADediting_380471chr13_100085449_-ncRNA_intronic
ADediting_380472chr13_100085516_-ncRNA_intronic
ADediting_380473chr13_100085555_-ncRNA_intronic
ADediting_380474chr13_100085701_-ncRNA_intronic
ADediting_380475chr13_100085730_-ncRNA_intronic
ADediting_380476chr13_100085731_-ncRNA_intronic
ADediting_380477chr13_100085734_-ncRNA_intronic
ADediting_380478chr13_100085755_-ncRNA_intronic
ADediting_380479chr13_100085809_-ncRNA_intronic
ADediting_380480chr13_100085819_-ncRNA_intronic
ADediting_380481chr13_100085820_-ncRNA_intronic
ADediting_380482chr13_100085843_-ncRNA_intronic
ADediting_380483chr13_100085854_-ncRNA_intronic
ADediting_380484chr13_100085947_-ncRNA_intronic
ADediting_380485chr13_100085956_-ncRNA_intronic
ADediting_380486chr13_100086479_-ncRNA_exonic
ADediting_380487chr13_100086515_-ncRNA_exonic
ADediting_380488chr13_100086527_-ncRNA_exonic
ADediting_380489chr13_100086530_-ncRNA_exonic
ADediting_380490chr13_100086534_-ncRNA_exonic
ADediting_380491chr13_100086556_-ncRNA_exonic
ADediting_380492chr13_100086575_-ncRNA_exonic
ADediting_380493chr13_100086595_-ncRNA_exonic
ADediting_380494chr13_100086598_-ncRNA_exonic
ADediting_380495chr13_100086601_-ncRNA_exonic
ADediting_380496chr13_100086622_-ncRNA_exonic
ADediting_380497chr13_100086690_-ncRNA_exonic
ADediting_380498chr13_100086692_-ncRNA_exonic
ADediting_1534543chr13_100069976_-ncRNA_intronic
ADediting_1534544chr13_100070051_-ncRNA_intronic
ADediting_1534545chr13_100070057_-ncRNA_intronic
ADediting_1534546chr13_100070070_-ncRNA_intronic
ADediting_1534547chr13_100070071_-ncRNA_intronic
ADediting_1534548chr13_100070136_-ncRNA_intronic
ADediting_1534549chr13_100070512_-ncRNA_intronic
ADediting_1534550chr13_100070644_-ncRNA_intronic
ADediting_1534551chr13_100070651_-ncRNA_intronic
ADediting_1534552chr13_100072871_-ncRNA_intronic
ADediting_1534553chr13_100072892_-ncRNA_intronic
ADediting_1534554chr13_100072933_-ncRNA_intronic
ADediting_1534555chr13_100072938_-ncRNA_intronic
ADediting_1534556chr13_100075525_-ncRNA_intronic
ADediting_1534557chr13_100075609_-ncRNA_intronic
ADediting_1534558chr13_100085723_-ncRNA_intronic
ADediting_1534559chr13_100085785_-ncRNA_intronic
ADediting_1534560chr13_100085936_-ncRNA_intronic
ADediting_1534561chr13_100086594_-ncRNA_exonic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_380346chr13_100059486_-SINEAluName=AluSq2
ADediting_380347chr13_100059595_-SINEAluName=AluSq2
ADediting_380348chr13_100061076_-SINEAluName=AluSp
ADediting_380349chr13_100065428_-SINEAluName=AluSz
ADediting_380350chr13_100065566_-SINEAluName=AluSq2
ADediting_380351chr13_100065580_-SINEAluName=AluSq2
ADediting_380352chr13_100065605_-SINEAluName=AluSq2
ADediting_380353chr13_100066767_-SINEAluName=AluSg
ADediting_380354chr13_100066789_-SINEAluName=AluSg
ADediting_380355chr13_100066792_-SINEAluName=AluSg
ADediting_380356chr13_100067708_-SINEAluName=AluSq10
ADediting_380357chr13_100067723_-SINEAluName=AluSq10
ADediting_380358chr13_100067877_-SINEAluName=AluSq10
ADediting_380359chr13_100067890_-SINEAluName=AluSq10
ADediting_380360chr13_100069915_-SINEAluName=AluJr
ADediting_380361chr13_100069927_-SINEAluName=AluJr
ADediting_380362chr13_100069937_-SINEAluName=AluJr
ADediting_380363chr13_100069977_-SINEAluName=AluJr
ADediting_380364chr13_100069997_-SINEAluName=AluJr
ADediting_380365chr13_100070067_-SINEAluName=AluJr
ADediting_380366chr13_100070078_-SINEAluName=AluJr
ADediting_380367chr13_100070083_-SINEAluName=AluJr
ADediting_380368chr13_100070090_-SINEAluName=AluJr
ADediting_380369chr13_100070091_-SINEAluName=AluJr
ADediting_380370chr13_100070122_-SINEAluName=AluJr
ADediting_380371chr13_100070127_-SINEAluName=AluJr
ADediting_380372chr13_100070128_-SINEAluName=AluJr
ADediting_380373chr13_100070132_-SINEAluName=AluJr
ADediting_380374chr13_100070141_-SINEAluName=AluJr
ADediting_380375chr13_100070168_-SINEAluName=AluJr
ADediting_380376chr13_100070169_-SINEAluName=AluJr
ADediting_380377chr13_100070500_-SINEAluName=AluJr
ADediting_380378chr13_100070506_-SINEAluName=AluJr
ADediting_380379chr13_100070516_-SINEAluName=AluJr
ADediting_380380chr13_100070524_-SINEAluName=AluJr
ADediting_380381chr13_100070529_-SINEAluName=AluJr
ADediting_380382chr13_100070532_-SINEAluName=AluJr
ADediting_380383chr13_100070577_-SINEAluName=AluJr
ADediting_380384chr13_100070590_-SINEAluName=AluJr
ADediting_380385chr13_100070594_-SINEAluName=AluJr
ADediting_380386chr13_100070596_-SINEAluName=AluJr
ADediting_380387chr13_100070602_-SINEAluName=AluJr
ADediting_380388chr13_100070605_-SINEAluName=AluJr
ADediting_380389chr13_100070624_-SINEAluName=AluJr
ADediting_380390chr13_100070634_-SINEAluName=AluJr
ADediting_380391chr13_100070653_-SINEAluName=AluJr
ADediting_380392chr13_100070657_-SINEAluName=AluJr
ADediting_380393chr13_100070664_-SINEAluName=AluJr
ADediting_380394chr13_100070673_-SINEAluName=AluJr
ADediting_380395chr13_100071180_-SINEAluName=AluSz6
ADediting_380396chr13_100071183_-SINEAluName=AluSz6
ADediting_380397chr13_100071195_-SINEAluName=AluSz6
ADediting_380398chr13_100071196_-SINEAluName=AluSz6
ADediting_380399chr13_100071222_-SINEAluName=AluSz6
ADediting_380400chr13_100071223_-SINEAluName=AluSz6
ADediting_380401chr13_100071236_-SINEAluName=AluSz6
ADediting_380402chr13_100072840_-SINEAluName=AluJo
ADediting_380403chr13_100073047_-SINEAluName=AluJo
ADediting_380404chr13_100073053_-SINEAluName=AluJo
ADediting_380405chr13_100073059_-SINEAluName=AluJo
ADediting_380406chr13_100073778_-SINEAluName=AluSx1
ADediting_380407chr13_100073781_-SINEAluName=AluSx1
ADediting_380408chr13_100073794_-SINEAluName=AluSx1
ADediting_380409chr13_100073813_-SINEAluName=AluSx1
ADediting_380410chr13_100073817_-SINEAluName=AluSx1
ADediting_380411chr13_100073836_-SINEAluName=AluSx1
ADediting_380412chr13_100073839_-SINEAluName=AluSx1
ADediting_380413chr13_100073845_-SINEAluName=AluSx1
ADediting_380414chr13_100073860_-SINEAluName=AluSx1
ADediting_380415chr13_100073908_-SINEAluName=AluSx1
ADediting_380416chr13_100073936_-SINEAluName=AluSx1
ADediting_380417chr13_100073948_-SINEAluName=AluSx1
ADediting_380418chr13_100074692_-SINEAluName=AluY
ADediting_380419chr13_100074696_-SINEAluName=AluY
ADediting_380420chr13_100074765_-SINEAluName=AluY
ADediting_380421chr13_100074955_-SINEAluName=AluSp
ADediting_380422chr13_100074960_-SINEAluName=AluSp
ADediting_380423chr13_100074961_-SINEAluName=AluSp
ADediting_380424chr13_100075004_-SINEAluName=AluSp
ADediting_380425chr13_100075007_-SINEAluName=AluSp
ADediting_380426chr13_100075093_-SINEAluName=AluSp
ADediting_380427chr13_100075111_-SINEAluName=AluSp
ADediting_380428chr13_100075163_-SINEAluName=AluSp
ADediting_380429chr13_100075164_-SINEAluName=AluSp
ADediting_380430chr13_100075391_-SINEAluName=AluJb
ADediting_380431chr13_100075400_-SINEAluName=AluJb
ADediting_380432chr13_100075413_-SINEAluName=AluJb
ADediting_380433chr13_100075430_-SINEAluName=AluJb
ADediting_380434chr13_100075463_-SINEAluName=AluJb
ADediting_380435chr13_100075465_-SINEAluName=AluJb
ADediting_380436chr13_100075475_-SINEAluName=AluJb
ADediting_380437chr13_100075481_-SINEAluName=AluJb
ADediting_380438chr13_100075490_-SINEAluName=AluJb
ADediting_380439chr13_100075499_-SINEAluName=AluJb
ADediting_380440chr13_100075535_-SINEAluName=AluJb
ADediting_380441chr13_100075538_-SINEAluName=AluJb
ADediting_380442chr13_100075539_-SINEAluName=AluJb
ADediting_380443chr13_100075547_-SINEAluName=AluJb
ADediting_380444chr13_100075552_-SINEAluName=AluJb
ADediting_380445chr13_100075564_-SINEAluName=AluJb
ADediting_380446chr13_100075565_-SINEAluName=AluJb
ADediting_380447chr13_100075595_-SINEAluName=AluJb
ADediting_380448chr13_100075603_-SINEAluName=AluJb
ADediting_380449chr13_100075614_-SINEAluName=AluJb
ADediting_380450chr13_100075625_-SINEAluName=AluJb
ADediting_380451chr13_100075641_-SINEAluName=AluJb
ADediting_380452chr13_100076467_-SINEAluName=AluY
ADediting_380453chr13_100076479_-SINEAluName=AluY
ADediting_380454chr13_100076489_-SINEAluName=AluY
ADediting_380455chr13_100076519_-SINEAluName=AluY
ADediting_380456chr13_100076534_-SINEAluName=AluY
ADediting_380457chr13_100076550_-SINEAluName=AluY
ADediting_380458chr13_100076556_-SINEAluName=AluY
ADediting_380459chr13_100076559_-SINEAluName=AluY
ADediting_380460chr13_100076601_-SINEAluName=AluY
ADediting_380461chr13_100076654_-SINEAluName=AluY
ADediting_380462chr13_100076660_-SINEAluName=AluY
ADediting_380463chr13_100076721_-SINEAluName=AluY
ADediting_380464chr13_100076984_-SINEAluName=AluSx
ADediting_380465chr13_100085305_-SINEAluName=AluY
ADediting_380466chr13_100085314_-SINEAluName=AluY
ADediting_380467chr13_100085315_-SINEAluName=AluY
ADediting_380468chr13_100085333_-SINEAluName=AluY
ADediting_380469chr13_100085337_-SINEAluName=AluY
ADediting_380470chr13_100085341_-SINEAluName=AluY
ADediting_380471chr13_100085449_-SINEAluName=AluY
ADediting_380472chr13_100085516_-SINEAluName=AluSx
ADediting_380473chr13_100085555_-SINEAluName=AluSx
ADediting_380474chr13_100085701_-SINEAluName=AluSx
ADediting_380475chr13_100085730_-SINEAluName=AluSx
ADediting_380476chr13_100085731_-SINEAluName=AluSx
ADediting_380477chr13_100085734_-SINEAluName=AluSx
ADediting_380478chr13_100085755_-SINEAluName=AluSx
ADediting_380479chr13_100085809_-SINEAluName=AluSx
ADediting_380480chr13_100085819_-SINEAluName=AluSx
ADediting_380481chr13_100085820_-SINEAluName=AluSx
ADediting_380482chr13_100085843_-SINEAluName=AluSx
ADediting_380483chr13_100085854_-SINEAluName=AluSx
ADediting_380484chr13_100085947_-SINEAluName=AluSx
ADediting_380485chr13_100085956_-SINEAluName=AluSx
ADediting_380486chr13_100086479_-SINEAluName=AluSg
ADediting_380487chr13_100086515_-SINEAluName=AluSg
ADediting_380488chr13_100086527_-SINEAluName=AluSg
ADediting_380489chr13_100086530_-SINEAluName=AluSg
ADediting_380490chr13_100086534_-SINEAluName=AluSg
ADediting_380491chr13_100086556_-SINEAluName=AluSg
ADediting_380492chr13_100086575_-SINEAluName=AluSg
ADediting_380493chr13_100086595_-SINEAluName=AluSg
ADediting_380494chr13_100086598_-SINEAluName=AluSg
ADediting_380495chr13_100086601_-SINEAluName=AluSg
ADediting_380496chr13_100086622_-SINEAluName=AluSg
ADediting_380497chr13_100086690_-SINEAluName=AluSg
ADediting_380498chr13_100086692_-SINEAluName=AluSg
ADediting_1534543chr13_100069976_-SINEAluName=AluJr
ADediting_1534544chr13_100070051_-SINEAluName=AluJr
ADediting_1534545chr13_100070057_-SINEAluName=AluJr
ADediting_1534546chr13_100070070_-SINEAluName=AluJr
ADediting_1534547chr13_100070071_-SINEAluName=AluJr
ADediting_1534548chr13_100070136_-SINEAluName=AluJr
ADediting_1534549chr13_100070512_-SINEAluName=AluJr
ADediting_1534550chr13_100070644_-SINEAluName=AluJr
ADediting_1534551chr13_100070651_-SINEAluName=AluJr
ADediting_1534552chr13_100072871_-SINEAluName=AluJo
ADediting_1534553chr13_100072892_-SINEAluName=AluJo
ADediting_1534554chr13_100072933_-SINEAluName=AluJo
ADediting_1534555chr13_100072938_-SINEAluName=AluJo
ADediting_1534556chr13_100075525_-SINEAluName=AluJb
ADediting_1534557chr13_100075609_-SINEAluName=AluJb
ADediting_1534558chr13_100085723_-SINEAluName=AluSx
ADediting_1534559chr13_100085785_-SINEAluName=AluSx
ADediting_1534560chr13_100085936_-SINEAluName=AluSx
ADediting_1534561chr13_100086594_-SINEAluName=AluSg

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RNA A-to-I editing events in the alternative splicing sites for PCCA-DT

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PCCA-DT

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
Soverview
Soverview

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
Soverview
Soverview
Soverview
Soverview
ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for PCCA-DT

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for PCCA-DT

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_380486chr13_100086479_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-652-3pchr131000864751000864817mer-m8100086474100086495142-15.8
ADediting_380487chr13_100086515_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-4437chr131000865121000865187mer-m8100086511100086531146-19.54
ADediting_380488chr13_100086527_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-6752-3pchr131000865271000865337mer-m8100086526100086545149-21.25
ADediting_380488chr13_100086527_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-6801-3pchr131000865251000865328mer-1a100086525100086544149-22.94
ADediting_380488chr13_100086527_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-6810-3pchr131000865251000865328mer-1a100086525100086547147-23.44
ADediting_380490chr13_100086534_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-1913chr131000865291000865357mer-m8100086528100086547148-25.3
ADediting_380490chr13_100086534_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-6849-3pchr131000865341000865407mer-m8100086533100086554142-15.67
ADediting_380491chr13_100086556_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-8052chr131000865511000865577mer-1a100086551100086571149-26.24
ADediting_380494chr13_100086598_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-222-5pchr131000865961000866038mer-1a100086596100086616141-9.8
ADediting_380494chr13_100086598_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-30a-3pchr131000865941000866018mer-1a100086594100086616153-12.93
ADediting_380494chr13_100086598_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-30d-3pchr131000865941000866018mer-1a100086594100086616153-15.05
ADediting_380494chr13_100086598_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-30e-3pchr131000865941000866018mer-1a100086594100086616153-11.41
ADediting_380494chr13_100086598_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-936chr131000865971000866048mer-1a100086597100086619159-23.71
ADediting_380495chr13_100086601_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-374b-3pchr131000865961000866038mer-1a100086596100086618147-12.2
ADediting_380495chr13_100086601_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-4756-3pchr131000866011000866077mer-m8100086600100086619159-20.2
ADediting_380496chr13_100086622_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-3190-5pchr131000866221000866287mer-m8100086621100086640151-19.64
ADediting_380496chr13_100086622_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-9851-5pchr131000866201000866267mer-1a100086620100086641140-22.98
ADediting_380497chr13_100086690_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-638chr131000866841000866907mer-1a100086684100086708149-27.99
ADediting_380498chr13_100086692_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-10399-5pchr131000866881000866947mer-m8100086687100086708144-10.39
ADediting_380498chr13_100086692_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-6504-3pchr131000866881000866947mer-m8100086687100086708152-15.11
ADediting_380498chr13_100086692_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-7151-3pchr131000866891000866968mer-1a100086689100086709144-16.51

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_380488chr13_100086527_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-1976chr131000865251000865328mer-1a100086525100086545153-26.47
ADediting_380489chr13_100086530_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-1976chr131000865251000865328mer-1a100086525100086545153-26.47
ADediting_380489chr13_100086530_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-6747-3pchr131000865271000865348mer-1a100086527100086547152-24.26
ADediting_380491chr13_100086556_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-10399-5pchr131000865551000865617mer-m8100086554100086573141-10.53
ADediting_380491chr13_100086556_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-5089-5pchr131000865511000865577mer-m8100086550100086570146-11.89
ADediting_380491chr13_100086556_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-6504-3pchr131000865551000865617mer-m8100086554100086578143-11.92
ADediting_380492chr13_100086575_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-6872-3pchr131000865721000865787mer-m8100086571100086591145-14.81
ADediting_380495chr13_100086601_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-6832-5pchr131000866001000866067mer-m8100086599100086621142-14.64
ADediting_380496chr13_100086622_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-4716-5pchr131000866171000866237mer-m8100086616100086638142-11.88
ADediting_380496chr13_100086622_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-4781-3pchr131000866191000866257mer-m8100086618100086641150-15.88

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1535951chr14_100874558_+ENSG00000274605.2ENST00000654763.1PCCA-DT-202hsa-miR-337-3pchr131000539891000539957mer-m8100053988100054008150-18.01
ADediting_286380chr11_79422188_-ENSG00000274605.2ENST00000654763.1PCCA-DT-202hsa-miR-5579-3pchr131000534881000534958mer-1a100053488100053509148-14.36
ADediting_496066chr15_66496985_-ENSG00000274605.2ENST00000612598.1PCCA-DT-201hsa-miR-4512chr131000865611000865677mer-m8100086560100086583152-22.16

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000274605.2ENST00000654763.1PCCA-DT-202hsa-miR-589-3pchr131000535741000535807mer-m8100053573100053598148-11.44

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PCCA-DT

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000612598.1lncRNASoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_380486ENST00000612598.1chr13_100086479_-465-266.10-265.70-284.60
ADediting_380487ENST00000612598.1chr13_100086515_-429-266.60-265.70-284.60
ADediting_380488ENST00000612598.1chr13_100086527_-417-265.90-265.70-284.60
ADediting_380489ENST00000612598.1chr13_100086530_-414-268.70-265.70-284.60
ADediting_380490ENST00000612598.1chr13_100086534_-410-268.40-265.70-284.60
ADediting_380491ENST00000612598.1chr13_100086556_-388-267.40-265.70-284.60
ADediting_380492ENST00000612598.1chr13_100086575_-369-266.00-265.70-284.60
ADediting_1534561ENST00000612598.1chr13_100086594_-350-266.10-265.70-284.60
ADediting_380493ENST00000612598.1chr13_100086595_-349-265.90-265.70-284.60
ADediting_380494ENST00000612598.1chr13_100086598_-346-265.80-265.70-284.60
ADediting_380495ENST00000612598.1chr13_100086601_-343-270.40-265.70-284.60
ADediting_380496ENST00000612598.1chr13_100086622_-322-265.40-265.70-284.60
ADediting_380497ENST00000612598.1chr13_100086690_-254-267.50-265.70-284.60
ADediting_380498ENST00000612598.1chr13_100086692_-252-265.90-265.70-284.60

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Relation with ADAR for PCCA-DT

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_380396chr13_100071183_-0.004513982251141480.2306642187388181.5045469190126e-050.3453365347833080.479315052132930.0581972134566713
CERADediting_380397chr13_100071195_-0.01629468265141820.1958773246557770.0001822417485430710.3009706254780740.3092926225455290.0835675889937846
DLPFCADediting_380476chr13_100085731_-0.01429416574606730.1390237283219760.7471224803196980.01838585558922467.65436363098338e-130.392226956030287
CERADediting_380484chr13_100085947_-0.003302945840971880.2384152069209460.0001659773378423550.3027651291908680.1063072297433790.13239189681711
CERADediting_380489chr13_100086530_-0.03502831028236690.1722721594629099.64550228818513e-050.3129622312721730.6008771490307830.0430545208105116

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC0.001662927969097060.1778953486280780.9150672080008380.006081785992365713.85610301615412e-590.758129455291051
AC2.76374123927113e-370.6942366625348018.41265740345358e-210.5457048468756242.17459686039519e-280.624045052011441
PCC0.3125319288529720.07345892718313190.5320734754371310.04548730351474684.68626029042771e-070.354976257456921
CER4.49739130695433e-100.4813718827305572.35539915202152e-100.4881276726936554.66838524502675e-090.455624938667421
TCX0.07065565899026230.1480209130915580.182323585745459-0.1094790539405771.03992184211605e-080.446298004889621
FP3.67494421668824e-080.3982805294405846.85173238335135e-070.3620290276324647.55142981454101e-070.360744930178048
PG0.0004284560079841710.2556571546420646.01424459284835e-080.384506477618780.07915125384864320.12906030696543
STG0.4937889163786230.07568962025774310.9161902348258890.01165622407911011.17757547347398e-050.45810145149011

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Relation with AD stages for PCCA-DT

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_380396chr13_100071183_-0.0004829750912329510.33019929569231

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER4.66857872698454e-050.38131979782449
TCX1.09132053056547e-060.452880997270675

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RelatedDrugs for PCCA-DT

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PCCA-DT

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource