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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for NPM2 |
 Gene summary |
| Gene information | Gene symbol | NPM2 | Gene ID | 10361 |
| Gene name | nucleophosmin/nucleoplasmin 2 | |
| Synonyms | - | |
| Cytomap | 8p21.3 | |
| Type of gene | protein-coding | |
| Description | nucleoplasmin-2 | |
| Modification date | 20200313 | |
| UniProtAcc | Q86SE8, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| NPM2 | GO:0006338 | chromatin remodeling | 12714744 |
Top |
RNA A-to-I events for NPM2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_1396061(22034852, +), ADediting_1396062(22034853, +), ADediting_1396063(22034861, +), ADediting_1396064(22034874, +), ADediting_1396065(22034875, +), ADediting_1396066(22034879, +), ADediting_1396067(22034883, +), ADediting_1396068(22034888, +), ADediting_1396069(22034893, +), ADediting_1396070(22034898, +), ADediting_1396071(22034912, +), ADediting_1396072(22034943, +), ADediting_1396073(22034947, +), ADediting_1396074(22034950, +), ADediting_1396075(22034954, +), ADediting_1396076(22034955, +), ADediting_1396077(22034957, +), ADediting_1396078(22034958, +), ADediting_1396079(22034961, +), ADediting_1396080(22034962, +), ADediting_1396081(22034986, +), ADediting_1396082(22034991, +), ADediting_1396083(22034995, +), ADediting_1396084(22034999, +), ADediting_1396085(22035008, +), ADediting_1396086(22035012, +), ADediting_1396087(22035018, +), ADediting_1396088(22035026, +), ADediting_1396089(22035038, +), ADediting_1396090(22035048, +), ADediting_1396091(22035053, +), ADediting_1396092(22035073, +), ADediting_1396093(22035297, +), ADediting_1396094(22035313, +), ADediting_1396095(22035317, +), ADediting_1396096(22035330, +), ADediting_1396097(22035335, +), ADediting_1396098(22035337, +), ADediting_1396099(22035338, +), ADediting_1396100(22035348, +), ADediting_1396101(22035373, +), ADediting_1396102(22035374, +), ADediting_1396103(22035377, +), ADediting_1396104(22035378, +), ADediting_1396105(22035386, +), ADediting_1396106(22035391, +), ADediting_1396107(22035399, +), ADediting_1396108(22035400, +), ADediting_1396109(22035403, +), ADediting_1396110(22035407, +), ADediting_1396111(22035413, +), ADediting_1396112(22035439, +), ADediting_1396113(22035440, +), ADediting_1396114(22035446, +), ADediting_1396115(22035447, +), ADediting_1396116(22035457, +), ADediting_1396117(22035463, +), ADediting_1396118(22035489, +), ADediting_1396119(22035494, +), ADediting_1396120(22035495, +), ADediting_1396121(22035496, +), ADediting_1396122(22035508, +), ADediting_1396123(22035509, +), ADediting_1396124(22035512, +), ADediting_1396125(22035513, +), ADediting_1396126(22035526, +), ADediting_1396127(22035535, +), ADediting_1396128(22035536, +), ADediting_1396129(22035539, +), ADediting_1396130(22035548, +), ADediting_1396131(22035550, +), ADediting_1396132(22035551, +), ADediting_1396133(22035660, +), ADediting_1396134(22035687, +), ADediting_1396135(22035696, +), ADediting_1396136(22035701, +), ADediting_1396137(22035714, +), ADediting_1396138(22035724, +), ADediting_1396139(22035732, +), ADediting_1396140(22035733, +), ADediting_1396141(22035738, +), ADediting_1396142(22035748, +), ADediting_1396143(22035752, +), ADediting_1396144(22035755, +), ADediting_1396145(22035786, +), ADediting_1396146(22035812, +), ADediting_1396147(22035813, +), ADediting_1396148(22035818, +), ADediting_1396149(22035822, +), ADediting_1396150(22035839, +), ADediting_1396151(22035848, +), ADediting_1396152(22035852, +), ADediting_1396153(22035867, +), ADediting_1396154(22035883, +), ADediting_1396155(22036128, +), ADediting_1396156(22036142, +), ADediting_1396157(22036151, +), ADediting_1396158(22036155, +), ADediting_1396159(22036164, +), ADediting_1396160(22036169, +), ADediting_1396161(22036174, +), ADediting_1396162(22036201, +), ADediting_1396163(22036203, +), ADediting_1396164(22036228, +), ADediting_1396165(22036229, +), ADediting_1396166(22036234, +), ADediting_1396167(22036244, +), ADediting_1590170(22034932, +), ADediting_1590171(22035758, +), ADediting_1590172(22035879, +), |
Top |
RNA editing positional annotations for NPM2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1396061 | chr8_22034852_+ | intronic |
| ADediting_1396062 | chr8_22034853_+ | intronic |
| ADediting_1396063 | chr8_22034861_+ | intronic |
| ADediting_1396064 | chr8_22034874_+ | intronic |
| ADediting_1396065 | chr8_22034875_+ | intronic |
| ADediting_1396066 | chr8_22034879_+ | intronic |
| ADediting_1396067 | chr8_22034883_+ | intronic |
| ADediting_1396068 | chr8_22034888_+ | intronic |
| ADediting_1396069 | chr8_22034893_+ | intronic |
| ADediting_1396070 | chr8_22034898_+ | intronic |
| ADediting_1396071 | chr8_22034912_+ | intronic |
| ADediting_1396072 | chr8_22034943_+ | intronic |
| ADediting_1396073 | chr8_22034947_+ | intronic |
| ADediting_1396074 | chr8_22034950_+ | intronic |
| ADediting_1396075 | chr8_22034954_+ | intronic |
| ADediting_1396076 | chr8_22034955_+ | intronic |
| ADediting_1396077 | chr8_22034957_+ | intronic |
| ADediting_1396078 | chr8_22034958_+ | intronic |
| ADediting_1396079 | chr8_22034961_+ | intronic |
| ADediting_1396080 | chr8_22034962_+ | intronic |
| ADediting_1396081 | chr8_22034986_+ | intronic |
| ADediting_1396082 | chr8_22034991_+ | intronic |
| ADediting_1396083 | chr8_22034995_+ | intronic |
| ADediting_1396084 | chr8_22034999_+ | intronic |
| ADediting_1396085 | chr8_22035008_+ | intronic |
| ADediting_1396086 | chr8_22035012_+ | intronic |
| ADediting_1396087 | chr8_22035018_+ | intronic |
| ADediting_1396088 | chr8_22035026_+ | intronic |
| ADediting_1396089 | chr8_22035038_+ | intronic |
| ADediting_1396090 | chr8_22035048_+ | intronic |
| ADediting_1396091 | chr8_22035053_+ | intronic |
| ADediting_1396092 | chr8_22035073_+ | intronic |
| ADediting_1396093 | chr8_22035297_+ | intronic |
| ADediting_1396094 | chr8_22035313_+ | intronic |
| ADediting_1396095 | chr8_22035317_+ | intronic |
| ADediting_1396096 | chr8_22035330_+ | intronic |
| ADediting_1396097 | chr8_22035335_+ | intronic |
| ADediting_1396098 | chr8_22035337_+ | intronic |
| ADediting_1396099 | chr8_22035338_+ | intronic |
| ADediting_1396100 | chr8_22035348_+ | intronic |
| ADediting_1396101 | chr8_22035373_+ | intronic |
| ADediting_1396102 | chr8_22035374_+ | intronic |
| ADediting_1396103 | chr8_22035377_+ | intronic |
| ADediting_1396104 | chr8_22035378_+ | intronic |
| ADediting_1396105 | chr8_22035386_+ | intronic |
| ADediting_1396106 | chr8_22035391_+ | intronic |
| ADediting_1396107 | chr8_22035399_+ | intronic |
| ADediting_1396108 | chr8_22035400_+ | intronic |
| ADediting_1396109 | chr8_22035403_+ | intronic |
| ADediting_1396110 | chr8_22035407_+ | intronic |
| ADediting_1396111 | chr8_22035413_+ | intronic |
| ADediting_1396112 | chr8_22035439_+ | intronic |
| ADediting_1396113 | chr8_22035440_+ | intronic |
| ADediting_1396114 | chr8_22035446_+ | intronic |
| ADediting_1396115 | chr8_22035447_+ | intronic |
| ADediting_1396116 | chr8_22035457_+ | intronic |
| ADediting_1396117 | chr8_22035463_+ | intronic |
| ADediting_1396118 | chr8_22035489_+ | intronic |
| ADediting_1396119 | chr8_22035494_+ | intronic |
| ADediting_1396120 | chr8_22035495_+ | intronic |
| ADediting_1396121 | chr8_22035496_+ | intronic |
| ADediting_1396122 | chr8_22035508_+ | intronic |
| ADediting_1396123 | chr8_22035509_+ | intronic |
| ADediting_1396124 | chr8_22035512_+ | intronic |
| ADediting_1396125 | chr8_22035513_+ | intronic |
| ADediting_1396126 | chr8_22035526_+ | intronic |
| ADediting_1396127 | chr8_22035535_+ | intronic |
| ADediting_1396128 | chr8_22035536_+ | intronic |
| ADediting_1396129 | chr8_22035539_+ | intronic |
| ADediting_1396130 | chr8_22035548_+ | intronic |
| ADediting_1396131 | chr8_22035550_+ | intronic |
| ADediting_1396132 | chr8_22035551_+ | intronic |
| ADediting_1396133 | chr8_22035660_+ | intronic |
| ADediting_1396134 | chr8_22035687_+ | intronic |
| ADediting_1396135 | chr8_22035696_+ | intronic |
| ADediting_1396136 | chr8_22035701_+ | intronic |
| ADediting_1396137 | chr8_22035714_+ | intronic |
| ADediting_1396138 | chr8_22035724_+ | intronic |
| ADediting_1396139 | chr8_22035732_+ | intronic |
| ADediting_1396140 | chr8_22035733_+ | intronic |
| ADediting_1396141 | chr8_22035738_+ | intronic |
| ADediting_1396142 | chr8_22035748_+ | intronic |
| ADediting_1396143 | chr8_22035752_+ | intronic |
| ADediting_1396144 | chr8_22035755_+ | intronic |
| ADediting_1396145 | chr8_22035786_+ | intronic |
| ADediting_1396146 | chr8_22035812_+ | intronic |
| ADediting_1396147 | chr8_22035813_+ | intronic |
| ADediting_1396148 | chr8_22035818_+ | intronic |
| ADediting_1396149 | chr8_22035822_+ | intronic |
| ADediting_1396150 | chr8_22035839_+ | intronic |
| ADediting_1396151 | chr8_22035848_+ | intronic |
| ADediting_1396152 | chr8_22035852_+ | intronic |
| ADediting_1396153 | chr8_22035867_+ | intronic |
| ADediting_1396154 | chr8_22035883_+ | intronic |
| ADediting_1396155 | chr8_22036128_+ | intronic |
| ADediting_1396156 | chr8_22036142_+ | intronic |
| ADediting_1396157 | chr8_22036151_+ | intronic |
| ADediting_1396158 | chr8_22036155_+ | intronic |
| ADediting_1396159 | chr8_22036164_+ | intronic |
| ADediting_1396160 | chr8_22036169_+ | intronic |
| ADediting_1396161 | chr8_22036174_+ | intronic |
| ADediting_1396162 | chr8_22036201_+ | intronic |
| ADediting_1396163 | chr8_22036203_+ | intronic |
| ADediting_1396164 | chr8_22036228_+ | intronic |
| ADediting_1396165 | chr8_22036229_+ | intronic |
| ADediting_1396166 | chr8_22036234_+ | intronic |
| ADediting_1396167 | chr8_22036244_+ | intronic |
| ADediting_1590170 | chr8_22034932_+ | intronic |
| ADediting_1590171 | chr8_22035758_+ | intronic |
| ADediting_1590172 | chr8_22035879_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1396061 | chr8_22034852_+ | SINE | Alu | Name=AluSz |
| ADediting_1396062 | chr8_22034853_+ | SINE | Alu | Name=AluSz |
| ADediting_1396063 | chr8_22034861_+ | SINE | Alu | Name=AluSz |
| ADediting_1396064 | chr8_22034874_+ | SINE | Alu | Name=AluSz |
| ADediting_1396065 | chr8_22034875_+ | SINE | Alu | Name=AluSz |
| ADediting_1396066 | chr8_22034879_+ | SINE | Alu | Name=AluSz |
| ADediting_1396067 | chr8_22034883_+ | SINE | Alu | Name=AluSz |
| ADediting_1396068 | chr8_22034888_+ | SINE | Alu | Name=AluSz |
| ADediting_1396069 | chr8_22034893_+ | SINE | Alu | Name=AluSz |
| ADediting_1396070 | chr8_22034898_+ | SINE | Alu | Name=AluSz |
| ADediting_1396071 | chr8_22034912_+ | SINE | Alu | Name=AluSz |
| ADediting_1396072 | chr8_22034943_+ | SINE | Alu | Name=AluSz |
| ADediting_1396073 | chr8_22034947_+ | SINE | Alu | Name=AluSz |
| ADediting_1396074 | chr8_22034950_+ | SINE | Alu | Name=AluSz |
| ADediting_1396075 | chr8_22034954_+ | SINE | Alu | Name=AluSz |
| ADediting_1396076 | chr8_22034955_+ | SINE | Alu | Name=AluSz |
| ADediting_1396077 | chr8_22034957_+ | SINE | Alu | Name=AluSz |
| ADediting_1396078 | chr8_22034958_+ | SINE | Alu | Name=AluSz |
| ADediting_1396079 | chr8_22034961_+ | SINE | Alu | Name=AluSz |
| ADediting_1396080 | chr8_22034962_+ | SINE | Alu | Name=AluSz |
| ADediting_1396081 | chr8_22034986_+ | SINE | Alu | Name=AluSz |
| ADediting_1396082 | chr8_22034991_+ | SINE | Alu | Name=AluSz |
| ADediting_1396083 | chr8_22034995_+ | SINE | Alu | Name=AluSz |
| ADediting_1396084 | chr8_22034999_+ | SINE | Alu | Name=AluSz |
| ADediting_1396085 | chr8_22035008_+ | SINE | Alu | Name=AluSz |
| ADediting_1396086 | chr8_22035012_+ | SINE | Alu | Name=AluSz |
| ADediting_1396087 | chr8_22035018_+ | SINE | Alu | Name=AluSz |
| ADediting_1396088 | chr8_22035026_+ | SINE | Alu | Name=AluSz |
| ADediting_1396089 | chr8_22035038_+ | SINE | Alu | Name=AluSz |
| ADediting_1396090 | chr8_22035048_+ | SINE | Alu | Name=AluSz |
| ADediting_1396091 | chr8_22035053_+ | SINE | Alu | Name=AluSz |
| ADediting_1396092 | chr8_22035073_+ | SINE | Alu | Name=AluSz |
| ADediting_1396093 | chr8_22035297_+ | SINE | Alu | Name=AluJr |
| ADediting_1396094 | chr8_22035313_+ | SINE | Alu | Name=AluJr |
| ADediting_1396095 | chr8_22035317_+ | SINE | Alu | Name=AluJr |
| ADediting_1396096 | chr8_22035330_+ | SINE | Alu | Name=AluJr |
| ADediting_1396097 | chr8_22035335_+ | SINE | Alu | Name=AluJr |
| ADediting_1396098 | chr8_22035337_+ | SINE | Alu | Name=AluJr |
| ADediting_1396099 | chr8_22035338_+ | SINE | Alu | Name=AluJr |
| ADediting_1396100 | chr8_22035348_+ | SINE | Alu | Name=AluJr |
| ADediting_1396101 | chr8_22035373_+ | SINE | Alu | Name=AluJr |
| ADediting_1396102 | chr8_22035374_+ | SINE | Alu | Name=AluJr |
| ADediting_1396103 | chr8_22035377_+ | SINE | Alu | Name=AluJr |
| ADediting_1396104 | chr8_22035378_+ | SINE | Alu | Name=AluJr |
| ADediting_1396105 | chr8_22035386_+ | SINE | Alu | Name=AluJr |
| ADediting_1396106 | chr8_22035391_+ | SINE | Alu | Name=AluJr |
| ADediting_1396107 | chr8_22035399_+ | SINE | Alu | Name=AluJr |
| ADediting_1396108 | chr8_22035400_+ | SINE | Alu | Name=AluJr |
| ADediting_1396109 | chr8_22035403_+ | SINE | Alu | Name=AluJr |
| ADediting_1396110 | chr8_22035407_+ | SINE | Alu | Name=AluJr |
| ADediting_1396111 | chr8_22035413_+ | SINE | Alu | Name=AluJr |
| ADediting_1396112 | chr8_22035439_+ | SINE | Alu | Name=AluJr |
| ADediting_1396113 | chr8_22035440_+ | SINE | Alu | Name=AluJr |
| ADediting_1396114 | chr8_22035446_+ | SINE | Alu | Name=AluJr |
| ADediting_1396115 | chr8_22035447_+ | SINE | Alu | Name=AluJr |
| ADediting_1396116 | chr8_22035457_+ | SINE | Alu | Name=AluJr |
| ADediting_1396117 | chr8_22035463_+ | SINE | Alu | Name=AluJr |
| ADediting_1396118 | chr8_22035489_+ | SINE | Alu | Name=AluJr |
| ADediting_1396119 | chr8_22035494_+ | SINE | Alu | Name=AluJr |
| ADediting_1396120 | chr8_22035495_+ | SINE | Alu | Name=AluJr |
| ADediting_1396121 | chr8_22035496_+ | SINE | Alu | Name=AluJr |
| ADediting_1396122 | chr8_22035508_+ | SINE | Alu | Name=AluJr |
| ADediting_1396123 | chr8_22035509_+ | SINE | Alu | Name=AluJr |
| ADediting_1396124 | chr8_22035512_+ | SINE | Alu | Name=AluJr |
| ADediting_1396125 | chr8_22035513_+ | SINE | Alu | Name=AluJr |
| ADediting_1396126 | chr8_22035526_+ | SINE | Alu | Name=AluJr |
| ADediting_1396127 | chr8_22035535_+ | SINE | Alu | Name=AluJr |
| ADediting_1396128 | chr8_22035536_+ | SINE | Alu | Name=AluJr |
| ADediting_1396129 | chr8_22035539_+ | SINE | Alu | Name=AluJr |
| ADediting_1396130 | chr8_22035548_+ | SINE | Alu | Name=AluJr |
| ADediting_1396131 | chr8_22035550_+ | SINE | Alu | Name=AluJr |
| ADediting_1396132 | chr8_22035551_+ | SINE | Alu | Name=AluJr |
| ADediting_1396133 | chr8_22035660_+ | SINE | Alu | Name=AluSz |
| ADediting_1396134 | chr8_22035687_+ | SINE | Alu | Name=AluSz |
| ADediting_1396135 | chr8_22035696_+ | SINE | Alu | Name=AluSz |
| ADediting_1396136 | chr8_22035701_+ | SINE | Alu | Name=AluSz |
| ADediting_1396137 | chr8_22035714_+ | SINE | Alu | Name=AluSz |
| ADediting_1396138 | chr8_22035724_+ | SINE | Alu | Name=AluSz |
| ADediting_1396139 | chr8_22035732_+ | SINE | Alu | Name=AluSz |
| ADediting_1396140 | chr8_22035733_+ | SINE | Alu | Name=AluSz |
| ADediting_1396141 | chr8_22035738_+ | SINE | Alu | Name=AluSz |
| ADediting_1396142 | chr8_22035748_+ | SINE | Alu | Name=AluSz |
| ADediting_1396143 | chr8_22035752_+ | SINE | Alu | Name=AluSz |
| ADediting_1396144 | chr8_22035755_+ | SINE | Alu | Name=AluSz |
| ADediting_1396145 | chr8_22035786_+ | SINE | Alu | Name=AluSz |
| ADediting_1396146 | chr8_22035812_+ | SINE | Alu | Name=AluSz |
| ADediting_1396147 | chr8_22035813_+ | SINE | Alu | Name=AluSz |
| ADediting_1396148 | chr8_22035818_+ | SINE | Alu | Name=AluSz |
| ADediting_1396149 | chr8_22035822_+ | SINE | Alu | Name=AluSz |
| ADediting_1396150 | chr8_22035839_+ | SINE | Alu | Name=AluSz |
| ADediting_1396151 | chr8_22035848_+ | SINE | Alu | Name=AluSz |
| ADediting_1396152 | chr8_22035852_+ | SINE | Alu | Name=AluSz |
| ADediting_1396153 | chr8_22035867_+ | SINE | Alu | Name=AluSz |
| ADediting_1396154 | chr8_22035883_+ | SINE | Alu | Name=AluSz |
| ADediting_1396155 | chr8_22036128_+ | SINE | Alu | Name=AluJb |
| ADediting_1396156 | chr8_22036142_+ | SINE | Alu | Name=AluJb |
| ADediting_1396157 | chr8_22036151_+ | SINE | Alu | Name=AluJb |
| ADediting_1396158 | chr8_22036155_+ | SINE | Alu | Name=AluJb |
| ADediting_1396159 | chr8_22036164_+ | SINE | Alu | Name=AluJb |
| ADediting_1396160 | chr8_22036169_+ | SINE | Alu | Name=AluJb |
| ADediting_1396161 | chr8_22036174_+ | SINE | Alu | Name=AluJb |
| ADediting_1396162 | chr8_22036201_+ | SINE | Alu | Name=AluJb |
| ADediting_1396163 | chr8_22036203_+ | SINE | Alu | Name=AluJb |
| ADediting_1396164 | chr8_22036228_+ | SINE | Alu | Name=AluJb |
| ADediting_1396165 | chr8_22036229_+ | SINE | Alu | Name=AluJb |
| ADediting_1396166 | chr8_22036234_+ | SINE | Alu | Name=AluJb |
| ADediting_1396167 | chr8_22036244_+ | SINE | Alu | Name=AluJb |
| ADediting_1590170 | chr8_22034932_+ | SINE | Alu | Name=AluSz |
| ADediting_1590171 | chr8_22035758_+ | SINE | Alu | Name=AluSz |
| ADediting_1590172 | chr8_22035879_+ | SINE | Alu | Name=AluSz |
Top |
RNA A-to-I editing events in the alternative splicing sites for NPM2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| A3SS | ADediting_1396145 | chr8_22035786_+ | 22035768:22035790 | 3ss | 2i | TACTAAAATACAAAATTCAGCTG | -0.18 | TACTAAAATACAAAATTCGGCTG | -8.13 |
| A3SS | ADediting_1396146 | chr8_22035812_+ | 22035800:22035822 | 3ss | 8i | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTGATCCCAGCTA | 2.04 |
| A3SS | ADediting_1396146 | chr8_22035812_+ | 22035800:22035822 | 3ss | 8i | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTGATCCCAGCTA | 2.04 |
| A3SS | ADediting_1396147 | chr8_22035813_+ | 22035800:22035822 | 3ss | 7i | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTAGTCCCAGCTA | -3.15 |
| A3SS | ADediting_1396147 | chr8_22035813_+ | 22035800:22035822 | 3ss | 7i | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTAGTCCCAGCTA | -3.15 |
| A3SS | ADediting_1396148 | chr8_22035818_+ | 22035800:22035822 | 3ss | 2i | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTAATCCCGGCTA | -6.52 |
| A3SS | ADediting_1396148 | chr8_22035818_+ | 22035800:22035822 | 3ss | 2i | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTAATCCCGGCTA | -6.52 |
| A3SS | ADediting_1396149 | chr8_22035822_+ | 22035800:22035822 | 3ss | 3e | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTAATCCCAGCTG | 2.21 |
| A3SS | ADediting_1396149 | chr8_22035822_+ | 22035800:22035822 | 3ss | 3e | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTAATCCCAGCTG | 2.21 |
| ES | ADediting_1396081 | chr8_22034986_+ | 22034973:22034995 | 3ss | 7i | TGGCATTCTTGTAATCCCAGCTA | 2.16 | TGGCATTCTTGTAGTCCCAGCTA | -2.42 |
| ES | ADediting_1396082 | chr8_22034991_+ | 22034973:22034995 | 3ss | 2i | TGGCATTCTTGTAATCCCAGCTA | 2.16 | TGGCATTCTTGTAATCCCGGCTA | -5.79 |
| ES | ADediting_1396083 | chr8_22034995_+ | 22034973:22034995 | 3ss | 3e | TGGCATTCTTGTAATCCCAGCTA | 2.16 | TGGCATTCTTGTAATCCCAGCTG | 2.93 |
| ES | ADediting_1396145 | chr8_22035786_+ | 22035768:22035790 | 3ss | 2i | TACTAAAATACAAAATTCAGCTG | -0.18 | TACTAAAATACAAAATTCGGCTG | -8.13 |
| ES | ADediting_1396145 | chr8_22035786_+ | 22035768:22035790 | 3ss | 2i | TACTAAAATACAAAATTCAGCTG | -0.18 | TACTAAAATACAAAATTCGGCTG | -8.13 |
| ES | ADediting_1396145 | chr8_22035786_+ | 22035768:22035790 | 3ss | 2i | TACTAAAATACAAAATTCAGCTG | -0.18 | TACTAAAATACAAAATTCGGCTG | -8.13 |
| ES | ADediting_1396146 | chr8_22035812_+ | 22035800:22035822 | 3ss | 8i | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTGATCCCAGCTA | 2.04 |
| ES | ADediting_1396147 | chr8_22035813_+ | 22035800:22035822 | 3ss | 7i | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTAGTCCCAGCTA | -3.15 |
| ES | ADediting_1396148 | chr8_22035818_+ | 22035800:22035822 | 3ss | 2i | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTAATCCCGGCTA | -6.52 |
| ES | ADediting_1396149 | chr8_22035822_+ | 22035800:22035822 | 3ss | 3e | GCATGTGCCTGTAATCCCAGCTA | 1.44 | GCATGTGCCTGTAATCCCAGCTG | 2.21 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for NPM2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for NPM2 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for NPM2 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_496066 | chr15_66496985_- | ENSG00000158806.14 | ENST00000289820.10 | NPM2-201 | hsa-miR-4512 | chr8 | 22036842 | 22036848 | 7mer-m8 | 22036829 | 22036849 | 153 | -22.23 |
| ADediting_496066 | chr15_66496985_- | ENSG00000158806.14 | ENST00000381530.9 | NPM2-202 | hsa-miR-4512 | chr8 | 22036842 | 22036848 | 7mer-m8 | 22036829 | 22036849 | 153 | -22.23 |
| ADediting_496066 | chr15_66496985_- | ENSG00000158806.14 | ENST00000397940.5 | NPM2-203 | hsa-miR-4512 | chr8 | 22036842 | 22036848 | 7mer-m8 | 22036829 | 22036849 | 153 | -22.23 |
| ADediting_496066 | chr15_66496985_- | ENSG00000158806.14 | ENST00000518119.6 | NPM2-204 | hsa-miR-4512 | chr8 | 22036842 | 22036848 | 7mer-m8 | 22036829 | 22036849 | 153 | -22.23 |
| ADediting_496066 | chr15_66496985_- | ENSG00000158806.14 | ENST00000521157.5 | NPM2-209 | hsa-miR-4512 | chr8 | 22036842 | 22036848 | 7mer-m8 | 22036829 | 22036849 | 153 | -22.23 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for NPM2 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for NPM2 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1396061 | chr8_22034852_+ | 0.0017708530095401 | 0.253198113227946 | 5.46987355872124e-05 | 0.323238815066106 | 0.00255164262406162 | 0.244641177551302 |
| CER | ADediting_1396063 | chr8_22034861_+ | 0.000789372808716989 | 0.271171566584715 | 2.19646210961356e-08 | 0.437330299316366 | 0.00237005589381388 | 0.246394049410689 |
| CER | ADediting_1396064 | chr8_22034874_+ | 0.00604653415090893 | 0.223181049658469 | 2.61946783181871e-07 | 0.4055914081296 | 6.74093860316943e-06 | 0.358282761275667 |
| TCX | ADediting_1396064 | chr8_22034874_+ | 0.00263278880163849 | 0.243894135558776 | 3.02170044226411e-09 | 0.460575618123733 | 0.255642647931959 | -0.0933935404097585 |
| CER | ADediting_1396065 | chr8_22034875_+ | 0.00187149319532373 | 0.251921600023722 | 3.56187007773299e-06 | 0.368180200023014 | 0.000899698395086781 | 0.268344119182867 |
| CER | ADediting_1396066 | chr8_22034879_+ | 0.00781245176135323 | 0.216423863569695 | 1.05241272952439e-06 | 0.38623263088882 | 0.000631203966256211 | 0.275935601505582 |
| CER | ADediting_1396068 | chr8_22034888_+ | 0.000281384928761306 | 0.292475663850796 | 1.40220832880409e-06 | 0.382079877104717 | 0.000205330199257874 | 0.298663813162299 |
| TCX | ADediting_1396068 | chr8_22034888_+ | 0.00065865291284612 | 0.275035251152109 | 9.01715510394111e-06 | 0.353656980780877 | 0.278454824017065 | 0.0890607084953754 |
| CER | ADediting_1396071 | chr8_22034912_+ | 0.030713046563766 | 0.176515098866049 | 3.09350135654643e-07 | 0.403339641138664 | 0.0471046520215929 | 0.162384668688032 |
| CER | ADediting_1396076 | chr8_22034955_+ | 0.00128606538027686 | 0.260463078011 | 2.51586424887349e-05 | 0.336735744470873 | 0.0243230789293568 | 0.183841797429706 |
| TCX | ADediting_1396078 | chr8_22034958_+ | 0.00133295871459258 | 0.259659778589111 | 1.08169827298931e-05 | 0.350726095928297 | 0.53148653971945 | -0.0514881442057966 |
| DLPFC | ADediting_1396079 | chr8_22034961_+ | 0.000762462741692029 | 0.190200394703761 | 3.62553031402876e-08 | 0.306519661644894 | 0.27998241628266 | 0.0615507134059832 |
| CER | ADediting_1396079 | chr8_22034961_+ | 0.000988683525845497 | 0.266286670605722 | 5.74460741707473e-05 | 0.322365490411415 | 0.0615296605206745 | 0.153037627649828 |
| TCX | ADediting_1396079 | chr8_22034961_+ | 0.000157396823796688 | 0.303778942763725 | 0.000162870698892377 | 0.303126427779189 | 0.955059940963384 | 0.00464006218046593 |
| DLPFC | ADediting_1396081 | chr8_22034986_+ | 0.000454062469041606 | 0.197980057989994 | 2.79839278377667e-09 | 0.329404022549261 | 0.0498608094113093 | 0.111489089448608 |
| CER | ADediting_1396081 | chr8_22034986_+ | 0.00720707306692183 | 0.218571626932908 | 4.6906562158899e-06 | 0.363949312081163 | 0.00135006462621599 | 0.259373162102619 |
| TCX | ADediting_1396081 | chr8_22034986_+ | 7.00504434146767e-05 | 0.318802810293026 | 2.79858845190259e-11 | 0.509389573149123 | 0.371761711877652 | -0.0734435394591006 |
| CER | ADediting_1396082 | chr8_22034991_+ | 7.8440198963847e-06 | 0.355882107842205 | 3.06199488815718e-09 | 0.460426013329864 | 0.00331520184384922 | 0.23832471395991 |
| TCX | ADediting_1396082 | chr8_22034991_+ | 0.00534326116785545 | 0.226374819032231 | 5.51229630854021e-09 | 0.453712753025729 | 0.61681363854591 | -0.0411823176945347 |
| TCX | ADediting_1396083 | chr8_22034995_+ | 0.0028327052687706 | 0.242138957860093 | 1.17492126162864e-09 | 0.471062220719213 | 0.901020085632475 | -0.0102403986225721 |
| DLPFC | ADediting_1396084 | chr8_22034999_+ | 0.0171286877464214 | 0.135321639232167 | 3.47955579885511e-08 | 0.306902513384373 | 0.0485953884772842 | 0.112108703525675 |
| CER | ADediting_1396084 | chr8_22034999_+ | 8.45016281160665e-07 | 0.38937090021271 | 1.82786465679309e-08 | 0.439557681508372 | 0.00716718242869356 | 0.21871871128601 |
| TCX | ADediting_1396084 | chr8_22034999_+ | 0.000482304853526175 | 0.281557222941723 | 4.47929140221463e-07 | 0.398268194156271 | 0.301324370052549 | -0.0849508723050398 |
| DLPFC | ADediting_1396085 | chr8_22035008_+ | 9.35274264007283e-05 | 0.220054260329155 | 1.12319570287816e-09 | 0.337119484773416 | 0.019089844418499 | 0.133062373952341 |
| TCX | ADediting_1396085 | chr8_22035008_+ | 0.00148047094641074 | 0.257291068990098 | 1.73951401720056e-05 | 0.342934500547957 | 0.638785575830895 | -0.0386350256634788 |
| CER | ADediting_1396086 | chr8_22035012_+ | 0.0209331850477724 | 0.188428456040481 | 6.78623957357883e-05 | 0.319375746362912 | 2.61863868841297e-05 | 0.336055152662721 |
| CER | ADediting_1396087 | chr8_22035018_+ | 0.982981930455113 | 0.00175632778692636 | 0.144535697229012 | 0.119708150927236 | 0.00011841407532247 | 0.309152319617766 |
| CER | ADediting_1396091 | chr8_22035053_+ | 0.146488657066026 | 0.11913305212574 | 0.000247661522193525 | 0.294999522953683 | 8.20811345101795e-07 | 0.389784024739384 |
| TCX | ADediting_1396091 | chr8_22035053_+ | 0.170065621643405 | 0.112608128954079 | 5.88360231064113e-05 | 0.321938466569197 | 0.833915246155281 | -0.017263672185854 |
| CER | ADediting_1396092 | chr8_22035073_+ | 0.0812010773050583 | 0.142841250007446 | 9.20932029252463e-06 | 0.353318864821918 | 0.000454125666754745 | 0.282799140320685 |
| CER | ADediting_1396094 | chr8_22035313_+ | 0.000580082932684354 | 0.277713026224571 | 0.000168709479478351 | 0.302452551100736 | 0.00499548461063306 | 0.228095584770858 |
| CER | ADediting_1396095 | chr8_22035317_+ | 0.00483412385319618 | 0.228930684334335 | 8.65684901785907e-07 | 0.389026965180929 | 0.000233825689181699 | 0.296128515279874 |
| CER | ADediting_1396096 | chr8_22035330_+ | 0.00040265232248356 | 0.285263824597181 | 2.12043192345979e-08 | 0.437758687713568 | 0.000110972386605081 | 0.310363540042039 |
| CER | ADediting_1396097 | chr8_22035335_+ | 2.70228515015321e-05 | 0.335519542034467 | 1.83193309069688e-09 | 0.466175346616954 | 0.00268704898373453 | 0.243406147821722 |
| TCX | ADediting_1396098 | chr8_22035337_+ | 0.00316782741286476 | 0.239433454934232 | 3.33184789379967e-05 | 0.331926559136784 | 0.0755417488305653 | -0.145548450026376 |
| CER | ADediting_1396099 | chr8_22035338_+ | 0.00029764690850994 | 0.291357484027716 | 4.53930051633435e-08 | 0.428368196970722 | 0.000505984872079004 | 0.280564351048266 |
| TCX | ADediting_1396099 | chr8_22035338_+ | 0.00734446836388325 | 0.218070499268081 | 1.67966964123074e-05 | 0.343515798199787 | 0.425969338671676 | -0.0654799051047262 |
| CER | ADediting_1396101 | chr8_22035373_+ | 1.37407101644764e-06 | 0.382375098064731 | 4.00946237727137e-08 | 0.429919013705712 | 2.09487505088469e-05 | 0.339828391056996 |
| CER | ADediting_1396103 | chr8_22035377_+ | 0.00134388112834357 | 0.25947638440453 | 3.15823501255479e-06 | 0.370010030945665 | 4.80030011760982e-05 | 0.325552849570282 |
| CER | ADediting_1396105 | chr8_22035386_+ | 0.000303087843724975 | 0.290995987002782 | 0.00011666909835125 | 0.309429821537058 | 0.00560234254250444 | 0.225156832993966 |
| TCX | ADediting_1396107 | chr8_22035399_+ | 0.0611912589681309 | 0.153235061418262 | 8.46131579609097e-05 | 0.31536861562593 | 0.148651856787355 | -0.118502780148969 |
| CER | ADediting_1396108 | chr8_22035400_+ | 0.00673070821367556 | 0.220377467261476 | 2.91383159440069e-06 | 0.371229216117943 | 0.000560089782960173 | 0.278447699970329 |
| CER | ADediting_1396109 | chr8_22035403_+ | 0.00374765502662286 | 0.2353101484976 | 2.27248805642515e-06 | 0.374961180118377 | 0.0712895800376683 | 0.147692459023742 |
| TCX | ADediting_1396110 | chr8_22035407_+ | 0.0852098097600997 | 0.141014034453313 | 0.000154949214871469 | 0.304077576632356 | 0.00160616563449334 | -0.255436894567514 |
| CER | ADediting_1396111 | chr8_22035413_+ | 0.00169418029552996 | 0.254215721145132 | 5.45296452770133e-06 | 0.361609279360177 | 0.0787993876295851 | 0.143970948106251 |
| TCX | ADediting_1396114 | chr8_22035446_+ | 0.263228186682567 | 0.0919245478732395 | 5.29882573475724e-05 | 0.323803561200491 | 0.0124421446493872 | -0.203631660888456 |
| CER | ADediting_1396118 | chr8_22035489_+ | 0.0411116869600221 | 0.166985568870557 | 6.91808829828907e-05 | 0.319028468724719 | 0.00785488304162985 | 0.216278927114857 |
| TCX | ADediting_1396119 | chr8_22035494_+ | 0.38796369761804 | 0.0709943658401849 | 3.36380362670128e-05 | 0.331761730128319 | 0.000812797863358117 | -0.270542143114337 |
| CER | ADediting_1396120 | chr8_22035495_+ | 0.00111450268445079 | 0.263649987043391 | 2.2618096134165e-07 | 0.407565174817171 | 0.00296279004907976 | 0.241056077088389 |
| CER | ADediting_1396121 | chr8_22035496_+ | 0.0279173457373849 | 0.17954306208013 | 0.000112455527049342 | 0.310116212220853 | 0.00334409298173735 | 0.238112582097825 |
| CER | ADediting_1396124 | chr8_22035512_+ | 0.000201204656699439 | 0.299057686077887 | 3.91593347519013e-06 | 0.366730465612159 | 0.00110632973733526 | 0.26381276407228 |
| CER | ADediting_1396125 | chr8_22035513_+ | 0.00093996317269446 | 0.267391051361456 | 5.74754264976213e-05 | 0.322356373061544 | 0.0342755387439775 | 0.172979186727739 |
| CER | ADediting_1396126 | chr8_22035526_+ | 7.3203904677065e-05 | 0.318005890168933 | 4.35268447027414e-08 | 0.428893606637506 | 0.000539687057155206 | 0.279222782624057 |
| TCX | ADediting_1396126 | chr8_22035526_+ | 0.00191754920026242 | 0.251358132580813 | 8.39260248289565e-05 | 0.315517739126333 | 0.524768739790805 | -0.0523323275031628 |
| CER | ADediting_1396129 | chr8_22035539_+ | 0.00362227930706749 | 0.236150433408269 | 6.02244660859884e-07 | 0.394150896822762 | 0.0315250102056768 | 0.175679700775011 |
| CER | ADediting_1396130 | chr8_22035548_+ | 0.00460120494316831 | 0.230181262726339 | 4.25446880241472e-05 | 0.327675493807474 | 0.104957050146811 | 0.13290104561466 |
| CER | ADediting_1396132 | chr8_22035551_+ | 0.000673938754243118 | 0.27454872667195 | 1.33196642341131e-05 | 0.347338137307559 | 0.0575393269197959 | 0.155424818475949 |
| TCX | ADediting_1396132 | chr8_22035551_+ | 0.00020358961244179 | 0.298829084570985 | 1.61163550487512e-05 | 0.344200865154501 | 0.14364217351486 | -0.119973238174985 |
| CER | ADediting_1396133 | chr8_22035660_+ | 1.11523553267653e-05 | 0.350231494253048 | 9.40004624895051e-07 | 0.387851767459819 | 0.00872411465433675 | 0.213452771201948 |
| CER | ADediting_1396134 | chr8_22035687_+ | 0.000828027295797004 | 0.270141810615857 | 5.77513527148351e-07 | 0.394737496206521 | 0.0234858073608363 | 0.184920919293613 |
| TCX | ADediting_1396134 | chr8_22035687_+ | 0.0753917996928802 | 0.145622374659703 | 7.93271463719678e-05 | 0.316546240518528 | 0.449851580241871 | -0.0621598817137559 |
| TCX | ADediting_1396135 | chr8_22035696_+ | 0.0655017544008741 | 0.150784206254631 | 1.9356722029004e-05 | 0.341153147918908 | 0.108025990364997 | -0.13175104703961 |
| CER | ADediting_1396137 | chr8_22035714_+ | 0.00164722219802975 | 0.254859857587279 | 2.83620864668688e-05 | 0.334693650542923 | 0.0154971284092125 | 0.197340202590915 |
| TCX | ADediting_1396137 | chr8_22035714_+ | 0.0473029031831537 | 0.162241013603974 | 0.00015654500142047 | 0.303882380103886 | 0.125295358731616 | -0.125717028008897 |
| CER | ADediting_1396139 | chr8_22035732_+ | 0.000161949822293466 | 0.303234758149386 | 8.45699382948696e-06 | 0.354682963673275 | 0.00137430106880127 | 0.258972696608145 |
| CER | ADediting_1396141 | chr8_22035738_+ | 1.50143027674976e-07 | 0.413007879147574 | 8.72998699741506e-11 | 0.49821658956358 | 1.38385411053412e-06 | 0.382271805143563 |
| TCX | ADediting_1396143 | chr8_22035752_+ | 0.158663291297959 | 0.115672789232839 | 5.80968209439671e-05 | 0.322164374297662 | 0.844911414180754 | 0.0161056037948135 |
| CER | ADediting_1396146 | chr8_22035812_+ | 0.000376773059088863 | 0.28661527004818 | 1.49119514277702e-07 | 0.413097925613129 | 0.0115943751260759 | 0.205617477290363 |
| CER | ADediting_1396147 | chr8_22035813_+ | 2.23819249760465e-06 | 0.375187969337807 | 1.47797484215805e-11 | 0.515486794493208 | 9.30537048956076e-06 | 0.353152357041938 |
| TCX | ADediting_1396147 | chr8_22035813_+ | 0.00143641207780997 | 0.25797511745722 | 1.27771785636248e-09 | 0.470145281057503 | 0.0491857649939609 | -0.160901066054254 |
| CER | ADediting_1396148 | chr8_22035818_+ | 0.0136984611215733 | 0.200896714599184 | 6.33311162427778e-05 | 0.320619433710144 | 0.000977719704032041 | 0.266530774756159 |
| TCX | ADediting_1396148 | chr8_22035818_+ | 0.000504037890634732 | 0.280644349455512 | 2.34442091142999e-08 | 0.43653599089715 | 0.00351451201118178 | -0.236893896255054 |
| CER | ADediting_1396149 | chr8_22035822_+ | 0.00108941138439742 | 0.264153246664529 | 1.48227860442558e-05 | 0.345582244159399 | 0.0750040126673493 | 0.145814105333539 |
| TCX | ADediting_1396149 | chr8_22035822_+ | 0.000476307618752571 | 0.281815815306176 | 7.66526120844055e-06 | 0.356248532551937 | 0.847206265016597 | -0.0158643249890506 |
| TCX | ADediting_1396150 | chr8_22035839_+ | 0.158853777823778 | 0.115620260833989 | 7.92815026471181e-06 | 0.355712381592004 | 0.0272840514395328 | -0.180264720618338 |
| CER | ADediting_1396151 | chr8_22035848_+ | 0.0227750186329197 | 0.185863277473235 | 2.30257875753033e-05 | 0.338235942098167 | 0.000199935085170034 | 0.299180406000406 |
| TCX | ADediting_1396152 | chr8_22035852_+ | 0.0129107963454526 | 0.202584293837146 | 1.36361426509356e-06 | 0.382486280520175 | 0.000381162425046271 | -0.286380121707626 |
| CER | ADediting_1396153 | chr8_22035867_+ | 0.00097270580449225 | 0.26664324383389 | 7.5566007410754e-05 | 0.317429739746955 | 0.0123145810405234 | 0.203922729529624 |
| TCX | ADediting_1396153 | chr8_22035867_+ | 0.426299456341918 | 0.0654332972586178 | 0.000103202340123079 | 0.31171198864436 | 0.134499901432119 | -0.122760358063303 |
| CER | ADediting_1396155 | chr8_22036128_+ | 0.0307200583567804 | 0.176507804794853 | 0.000166057551004919 | 0.302755884141903 | 0.070049798843825 | 0.148337071417675 |
| CER | ADediting_1396156 | chr8_22036142_+ | 0.00637703460962281 | 0.221793293473117 | 3.26760616769612e-06 | 0.36949321278051 | 0.00904586664230093 | 0.212469608586454 |
| CER | ADediting_1396157 | chr8_22036151_+ | 0.00355570082315438 | 0.236607351347256 | 4.07747036658217e-05 | 0.328419009605773 | 0.096016035049805 | 0.136409528014614 |
| CER | ADediting_1396158 | chr8_22036155_+ | 0.000120139725417852 | 0.308881619581197 | 4.47846467415711e-08 | 0.428537163859394 | 0.00612613645944157 | 0.222840733499601 |
| CER | ADediting_1396159 | chr8_22036164_+ | 0.00324277432735376 | 0.238863927372066 | 4.73586008722345e-06 | 0.36380082272966 | 0.00243028185874921 | 0.245799592013769 |
| CER | ADediting_1396160 | chr8_22036169_+ | 0.00133338097130704 | 0.259652663175807 | 7.55041075025038e-07 | 0.390968158984716 | 0.0109615337127009 | 0.207184762841667 |
| CER | ADediting_1396161 | chr8_22036174_+ | 0.00012815363711029 | 0.307670204778091 | 1.00839254620388e-09 | 0.472726223915442 | 0.000206299275407818 | 0.298572361506712 |
| CER | ADediting_1396164 | chr8_22036228_+ | 0.000598814107198526 | 0.27704559882703 | 7.25649012052404e-06 | 0.357117797965398 | 0.138663438611291 | 0.121473705988579 |
| TCX | ADediting_1396166 | chr8_22036234_+ | 0.038970399651032 | 0.168766392722162 | 3.15988461144373e-05 | 0.33283991473488 | 0.0521605588288221 | -0.158868392492208 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 5.81870639936217e-15 | 0.42406482521225 | 1.25269489594794e-34 | 0.622330125085972 | 0.00963876041215844 | 0.146814028133094 |
| AC | 1.33496565842081e-50 | 0.771434351930764 | 2.37252928007915e-54 | 0.788847709861798 | 3.3927171531712e-05 | 0.258986821167993 |
| PCC | 7.37637006800718e-35 | 0.743465855017316 | 2.59223838954588e-42 | 0.791695773212975 | 0.402543652948506 | 0.0609130737132705 |
| CER | 7.6409322880608e-08 | 0.421775314073485 | 1.76098964763797e-05 | 0.342730487499155 | 0.163274007911878 | 0.11441437048621 |
| TCX | 1.23254303815182e-08 | 0.444282516896362 | 1.40527230959332e-20 | 0.666031829302977 | 2.53213605107379e-06 | -0.373342727845321 |
| FP | 5.31415319556977e-24 | 0.664079538001328 | 5.24663450639741e-15 | 0.542447093097428 | 0.196807575250974 | 0.0971976414790834 |
| IFG | 0.000668228547933981 | 0.633889893194143 | 0.00180744839945596 | 0.5924054512485 | 0.516508573592094 | -0.136109686124929 |
| PG | 9.59997526571131e-15 | 0.528003435581978 | 1.57134970644884e-19 | 0.59945752313322 | 0.147053141138766 | -0.106736147835853 |
| STG | 4.66228963883236e-26 | 0.863178654865856 | 1.0993484974027e-18 | 0.784340377465693 | 0.459276185559079 | 0.0818355396222417 |
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Relation with AD stages for NPM2 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_1396061 | chr8_22034852_+ | 0.000113954593314378 | 0.362799296355156 |
| CER | ADediting_1396062 | chr8_22034853_+ | 0.000907155291878219 | 0.314766482264826 |
| CER | ADediting_1396064 | chr8_22034874_+ | 1.95907815262005e-06 | 0.439405186351154 |
| CER | ADediting_1396065 | chr8_22034875_+ | 0.000294375917012726 | 0.341779433794949 |
| CER | ADediting_1396066 | chr8_22034879_+ | 0.00030723573180382 | 0.340796944679945 |
| CER | ADediting_1396081 | chr8_22034986_+ | 0.000111300522289863 | 0.363303107571225 |
| CER | ADediting_1396084 | chr8_22034999_+ | 0.00146258430600525 | 0.302501740158106 |
| CER | ADediting_1396086 | chr8_22035012_+ | 0.000831432810632421 | 0.316949613009364 |
| CER | ADediting_1396092 | chr8_22035073_+ | 2.40910304868297e-05 | 0.39436534698495 |
| CER | ADediting_1396096 | chr8_22035330_+ | 0.000420796430846132 | 0.333468289520977 |
| CER | ADediting_1396101 | chr8_22035373_+ | 0.000112229213803396 | 0.363125559582201 |
| CER | ADediting_1396103 | chr8_22035377_+ | 2.88141337683618e-05 | 0.390889212294421 |
| CER | ADediting_1396107 | chr8_22035399_+ | 0.00017014049399212 | 0.354099648892479 |
| CER | ADediting_1396108 | chr8_22035400_+ | 0.000462875336657182 | 0.331211424802084 |
| CER | ADediting_1396109 | chr8_22035403_+ | 0.000529661998031975 | 0.32799018239587 |
| CER | ADediting_1396118 | chr8_22035489_+ | 7.73969940830254e-05 | 0.370966139615674 |
| CER | ADediting_1396119 | chr8_22035494_+ | 0.00110473994881868 | 0.309769680221731 |
| CER | ADediting_1396120 | chr8_22035495_+ | 0.000365094002239472 | 0.336799127370421 |
| CER | ADediting_1396121 | chr8_22035496_+ | 2.17677494638297e-05 | 0.396317266173511 |
| CER | ADediting_1396124 | chr8_22035512_+ | 4.28753255691849e-05 | 0.383029880262715 |
| CER | ADediting_1396125 | chr8_22035513_+ | 0.000433303599764565 | 0.332776556211139 |
| CER | ADediting_1396126 | chr8_22035526_+ | 2.18695407704094e-05 | 0.396227737482717 |
| CER | ADediting_1396129 | chr8_22035539_+ | 0.000250048093820841 | 0.345500168916631 |
| CER | ADediting_1396130 | chr8_22035548_+ | 0.000618133115344647 | 0.324254710602162 |
| CER | ADediting_1396132 | chr8_22035551_+ | 0.000835103977478575 | 0.316839656372921 |
| CER | ADediting_1396138 | chr8_22035724_+ | 0.000193834241340049 | 0.3512150907666 |
| CER | ADediting_1396139 | chr8_22035732_+ | 7.08010790699902e-05 | 0.372816059731003 |
| CER | ADediting_1396141 | chr8_22035738_+ | 0.000123058964707422 | 0.361150234774454 |
| CER | ADediting_1396147 | chr8_22035813_+ | 0.000254104174065408 | 0.345135371530945 |
| CER | ADediting_1396158 | chr8_22036155_+ | 0.000350689325062475 | 0.337736641436499 |
| CER | ADediting_1396161 | chr8_22036174_+ | 0.000171781510213788 | 0.353888217022736 |
| TCX | ADediting_1396077 | chr8_22034957_+ | 8.13559089453554e-05 | 0.37322292412071 |
| TCX | ADediting_1396079 | chr8_22034961_+ | 9.76302444340045e-05 | 0.36935869095839 |
| TCX | ADediting_1396084 | chr8_22034999_+ | 0.000340161647541977 | 0.341501883156085 |
| TCX | ADediting_1396107 | chr8_22035399_+ | 0.000556254665415197 | 0.329776205347562 |
| TCX | ADediting_1396112 | chr8_22035439_+ | 0.000490741892506919 | 0.332807980526832 |
| IFG | ADediting_1396064 | chr8_22034874_+ | 0.0354713369979928 | 0.422303326441651 |
| IFG | ADediting_1396069 | chr8_22034893_+ | 0.0354713369979928 | 0.422303326441651 |
| IFG | ADediting_1396078 | chr8_22034958_+ | 0.0354713369979928 | 0.422303326441651 |
| IFG | ADediting_1396082 | chr8_22034991_+ | 0.0476320457660767 | 0.399894503823281 |
| IFG | ADediting_1396112 | chr8_22035439_+ | 0.0354713369979928 | 0.422303326441651 |
| IFG | ADediting_1396114 | chr8_22035446_+ | 0.0354713369979928 | 0.422303326441651 |
| IFG | ADediting_1396124 | chr8_22035512_+ | 0.0354713369979928 | 0.422303326441651 |
| IFG | ADediting_1396125 | chr8_22035513_+ | 0.0113059937049014 | 0.497952103823781 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for NPM2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NPM2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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