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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for LINC01273 |
 Gene summary |
| Gene information | Gene symbol | LINC01273 | Gene ID | 101927541 |
| Gene name | long intergenic non-protein coding RNA 1273 | |
| Synonyms | - | |
| Cytomap | 20q13.13 | |
| Type of gene | ncRNA | |
| Description | - | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for LINC01273 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_943985(50173200, +), ADediting_943986(50173207, +), ADediting_943987(50173250, +), ADediting_943988(50173255, +), ADediting_943989(50173293, +), ADediting_943990(50173315, +), ADediting_943991(50173317, +), ADediting_943992(50173416, +), ADediting_943993(50173443, +), ADediting_943994(50174058, +), ADediting_943995(50174067, +), ADediting_943996(50174152, +), ADediting_943997(50174636, +), ADediting_943998(50175770, +), |
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RNA editing positional annotations for LINC01273 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_943985 | chr20_50173200_+ | ncRNA_exonic;splicing |
| ADediting_943986 | chr20_50173207_+ | ncRNA_exonic |
| ADediting_943987 | chr20_50173250_+ | ncRNA_exonic |
| ADediting_943988 | chr20_50173255_+ | ncRNA_exonic |
| ADediting_943989 | chr20_50173293_+ | ncRNA_exonic |
| ADediting_943990 | chr20_50173315_+ | ncRNA_exonic |
| ADediting_943991 | chr20_50173317_+ | ncRNA_exonic |
| ADediting_943992 | chr20_50173416_+ | ncRNA_exonic |
| ADediting_943993 | chr20_50173443_+ | ncRNA_exonic |
| ADediting_943994 | chr20_50174058_+ | ncRNA_intronic |
| ADediting_943995 | chr20_50174067_+ | ncRNA_intronic |
| ADediting_943996 | chr20_50174152_+ | ncRNA_intronic |
| ADediting_943997 | chr20_50174636_+ | ncRNA_intronic |
| ADediting_943998 | chr20_50175770_+ | ncRNA_intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_943985 | chr20_50173200_+ | SINE | Alu | Name=AluJo |
| ADediting_943986 | chr20_50173207_+ | SINE | Alu | Name=AluJo |
| ADediting_943987 | chr20_50173250_+ | SINE | Alu | Name=AluJo |
| ADediting_943988 | chr20_50173255_+ | SINE | Alu | Name=AluJo |
| ADediting_943989 | chr20_50173293_+ | SINE | Alu | Name=AluJo |
| ADediting_943990 | chr20_50173315_+ | SINE | Alu | Name=AluJo |
| ADediting_943991 | chr20_50173317_+ | SINE | Alu | Name=AluJo |
| ADediting_943992 | chr20_50173416_+ | SINE | Alu | Name=AluJo |
| ADediting_943993 | chr20_50173443_+ | SINE | Alu | Name=AluJo |
| ADediting_943994 | chr20_50174058_+ | SINE | Alu | Name=AluSx1 |
| ADediting_943995 | chr20_50174067_+ | SINE | Alu | Name=AluSx1 |
| ADediting_943996 | chr20_50174152_+ | SINE | Alu | Name=AluSx1 |
| ADediting_943997 | chr20_50174636_+ | SINE | Alu | Name=AluJo |
| ADediting_943998 | chr20_50175770_+ | SINE | Alu | Name=AluSx1 |
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RNA A-to-I editing events in the alternative splicing sites for LINC01273 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| RI | ADediting_943985 | chr20_50173200_+ | 50173182:50173204 | 3ss | 2i | TCTTTGTTTTTTGTGACAAGGTC | 6.66 | TCTTTGTTTTTTGTGACAGGGTC | -1.30 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LINC01273 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for LINC01273 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for LINC01273 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_943985 | chr20_50173200_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-10a-5p | chr20 | 50173197 | 50173203 | 7mer-m8 | 50173182 | 50173204 | 140 | -11.91 |
| ADediting_943985 | chr20_50173200_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-10b-5p | chr20 | 50173197 | 50173203 | 7mer-m8 | 50173178 | 50173204 | 148 | -12.51 |
| ADediting_943985 | chr20_50173200_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-339-5p | chr20 | 50173196 | 50173202 | 7mer-m8 | 50173182 | 50173203 | 148 | -17.67 |
| ADediting_943985 | chr20_50173200_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-4725-5p | chr20 | 50173198 | 50173204 | 7mer-m8 | 50173184 | 50173205 | 141 | -15.96 |
| ADediting_943985 | chr20_50173200_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-504-5p | chr20 | 50173198 | 50173204 | 7mer-m8 | 50173186 | 50173205 | 143 | -18 |
| ADediting_943985 | chr20_50173200_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-6773-3p | chr20 | 50173194 | 50173200 | 7mer-m8 | 50173180 | 50173201 | 140 | -11.16 |
| ADediting_943986 | chr20_50173207_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-589-3p | chr20 | 50173206 | 50173212 | 7mer-m8 | 50173006 | 50173213 | 145 | -14.08 |
| ADediting_943986 | chr20_50173207_+ | ENSG00000231742.6 | ENST00000661469.1 | LINC01273-204 | hsa-miR-589-3p | chr20 | 50173206 | 50173212 | 7mer-m8 | 50173006 | 50173213 | 145 | -14.08 |
| ADediting_943986 | chr20_50173207_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-589-3p | chr20 | 50173206 | 50173212 | 7mer-m8 | 50173191 | 50173213 | 152 | -15.71 |
| ADediting_943990 | chr20_50173315_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-17-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50173319 | 154 | -20.36 |
| ADediting_943990 | chr20_50173315_+ | ENSG00000231742.6 | ENST00000661469.1 | LINC01273-204 | hsa-miR-17-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50176281 | 154 | -20.36 |
| ADediting_943990 | chr20_50173315_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-17-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50173319 | 154 | -20.36 |
| ADediting_943990 | chr20_50173315_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-17-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50173319 | 154 | -20.36 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-100-5p | chr20 | 50173314 | 50173320 | 7mer-m8 | 50173301 | 50173321 | 160 | -22.54 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-99a-5p | chr20 | 50173314 | 50173320 | 7mer-m8 | 50173301 | 50173321 | 160 | -21.42 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-99b-5p | chr20 | 50173314 | 50173320 | 7mer-m8 | 50173298 | 50173321 | 155 | -27.77 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-100-5p | chr20 | 50173314 | 50173320 | 7mer-m8 | 50173301 | 50173321 | 160 | -22.54 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-99a-5p | chr20 | 50173314 | 50173320 | 7mer-m8 | 50173301 | 50173321 | 160 | -21.42 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-99b-5p | chr20 | 50173314 | 50173320 | 7mer-m8 | 50173298 | 50173321 | 155 | -27.77 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-100-5p | chr20 | 50173314 | 50173320 | 7mer-m8 | 50173301 | 50173321 | 160 | -22.54 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-99a-5p | chr20 | 50173314 | 50173320 | 7mer-m8 | 50173301 | 50173321 | 160 | -21.42 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-99b-5p | chr20 | 50173314 | 50173320 | 7mer-m8 | 50173298 | 50173321 | 155 | -27.77 |
| ADediting_943992 | chr20_50173416_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-1199-5p | chr20 | 50173410 | 50173416 | 7mer-m8 | 50173398 | 50173417 | 152 | -26.5 |
| ADediting_943992 | chr20_50173416_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-6751-3p | chr20 | 50173410 | 50173416 | 7mer-m8 | 50173397 | 50173417 | 141 | -13.95 |
| ADediting_943992 | chr20_50173416_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-1199-5p | chr20 | 50173410 | 50173416 | 7mer-m8 | 50173398 | 50173417 | 152 | -26.5 |
| ADediting_943992 | chr20_50173416_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-6751-3p | chr20 | 50173410 | 50173416 | 7mer-m8 | 50173397 | 50173417 | 141 | -13.95 |
| ADediting_943992 | chr20_50173416_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-1199-5p | chr20 | 50173410 | 50173416 | 7mer-m8 | 50173398 | 50173417 | 152 | -26.5 |
| ADediting_943992 | chr20_50173416_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-6751-3p | chr20 | 50173410 | 50173416 | 7mer-m8 | 50173397 | 50173417 | 141 | -13.95 |
| ADediting_943993 | chr20_50173443_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-3189-3p | chr20 | 50173438 | 50173444 | 7mer-m8 | 50173423 | 50173445 | 145 | -20.29 |
| ADediting_943993 | chr20_50173443_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-6813-3p | chr20 | 50173439 | 50173445 | 7mer-m8 | 50173426 | 50173446 | 140 | -15.63 |
| ADediting_943993 | chr20_50173443_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-3189-3p | chr20 | 50173438 | 50173444 | 7mer-m8 | 50173423 | 50173445 | 145 | -20.29 |
| ADediting_943993 | chr20_50173443_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-6813-3p | chr20 | 50173439 | 50173445 | 7mer-m8 | 50173426 | 50173446 | 140 | -15.63 |
| ADediting_943993 | chr20_50173443_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-3189-3p | chr20 | 50173438 | 50173444 | 7mer-m8 | 50173423 | 50173445 | 145 | -20.29 |
| ADediting_943993 | chr20_50173443_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-6813-3p | chr20 | 50173439 | 50173445 | 7mer-m8 | 50173426 | 50173446 | 140 | -15.63 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_943988 | chr20_50173255_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-17-3p | chr20 | 50173250 | 50173256 | 7mer-m8 | 50173235 | 50173257 | 151 | -21.09 |
| ADediting_943988 | chr20_50173255_+ | ENSG00000231742.6 | ENST00000661469.1 | LINC01273-204 | hsa-miR-17-3p | chr20 | 50173250 | 50173256 | 7mer-m8 | 50173235 | 50173257 | 151 | -21.09 |
| ADediting_943988 | chr20_50173255_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-17-3p | chr20 | 50173250 | 50173256 | 7mer-m8 | 50173235 | 50173257 | 151 | -21.09 |
| ADediting_943988 | chr20_50173255_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-17-3p | chr20 | 50173250 | 50173256 | 7mer-m8 | 50173235 | 50173257 | 151 | -21.09 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-4478 | chr20 | 50173291 | 50173297 | 7mer-m8 | 50173282 | 50173298 | 155 | -24.85 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-485-5p | chr20 | 50173292 | 50173298 | 7mer-m8 | 50173279 | 50173299 | 149 | -17.06 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-7160-5p | chr20 | 50173289 | 50173295 | 7mer-m8 | 50173278 | 50173296 | 147 | -18.56 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000661469.1 | LINC01273-204 | hsa-miR-4478 | chr20 | 50173291 | 50173297 | 7mer-m8 | 50173282 | 50173298 | 155 | -24.85 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000661469.1 | LINC01273-204 | hsa-miR-485-5p | chr20 | 50173292 | 50173298 | 7mer-m8 | 50173279 | 50173299 | 149 | -17.06 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000661469.1 | LINC01273-204 | hsa-miR-7160-5p | chr20 | 50173289 | 50173295 | 7mer-m8 | 50173278 | 50173296 | 147 | -18.56 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-4478 | chr20 | 50173291 | 50173297 | 7mer-m8 | 50173282 | 50173298 | 155 | -24.85 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-485-5p | chr20 | 50173292 | 50173298 | 7mer-m8 | 50173279 | 50173299 | 149 | -17.06 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-7160-5p | chr20 | 50173289 | 50173295 | 7mer-m8 | 50173278 | 50173296 | 147 | -18.56 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-4478 | chr20 | 50173291 | 50173297 | 7mer-m8 | 50173282 | 50173298 | 155 | -24.85 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-485-5p | chr20 | 50173292 | 50173298 | 7mer-m8 | 50173279 | 50173299 | 149 | -17.06 |
| ADediting_943989 | chr20_50173293_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-7160-5p | chr20 | 50173289 | 50173295 | 7mer-m8 | 50173278 | 50173296 | 147 | -18.56 |
| ADediting_943990 | chr20_50173315_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-20b-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50173319 | 153 | -18.18 |
| ADediting_943990 | chr20_50173315_+ | ENSG00000231742.6 | ENST00000661469.1 | LINC01273-204 | hsa-miR-146b-3p | chr20 | 50173315 | 50176283 | 7mer-1a | 50173299 | 50176283 | 154 | -28.02 |
| ADediting_943990 | chr20_50173315_+ | ENSG00000231742.6 | ENST00000661469.1 | LINC01273-204 | hsa-miR-20b-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50176281 | 153 | -18.18 |
| ADediting_943990 | chr20_50173315_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-20b-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50173319 | 153 | -18.18 |
| ADediting_943990 | chr20_50173315_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-20b-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50173319 | 153 | -18.18 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-20b-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50173319 | 153 | -18.18 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-6804-3p | chr20 | 50173316 | 50173322 | 7mer-m8 | 50173301 | 50173323 | 155 | -23.45 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000661469.1 | LINC01273-204 | hsa-miR-146b-3p | chr20 | 50173315 | 50176283 | 7mer-1a | 50173299 | 50176283 | 154 | -28.02 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000661469.1 | LINC01273-204 | hsa-miR-20b-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50176281 | 153 | -18.18 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-20b-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50173319 | 153 | -18.18 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-6804-3p | chr20 | 50173316 | 50173322 | 7mer-m8 | 50173301 | 50173323 | 155 | -23.45 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-20b-3p | chr20 | 50173312 | 50173318 | 7mer-m8 | 50173297 | 50173319 | 153 | -18.18 |
| ADediting_943991 | chr20_50173317_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-6804-3p | chr20 | 50173316 | 50173322 | 7mer-m8 | 50173301 | 50173323 | 155 | -23.45 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-381-3p | chr20 | 50173348 | 50173354 | 7mer-m8 | 50173334 | 50173355 | 151 | -12.38 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-381-3p | chr20 | 50173348 | 50173354 | 7mer-m8 | 50173334 | 50173355 | 151 | -12.38 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-381-3p | chr20 | 50173348 | 50173354 | 7mer-m8 | 50173334 | 50173355 | 151 | -12.38 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-381-3p | chr20 | 50173348 | 50173354 | 7mer-m8 | 50173334 | 50173355 | 151 | -12.38 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000231742.6 | ENST00000664618.1 | LINC01273-205 | hsa-miR-381-3p | chr20 | 50173348 | 50173354 | 7mer-m8 | 50173334 | 50173355 | 151 | -12.38 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000231742.6 | ENST00000665536.1 | LINC01273-206 | hsa-miR-381-3p | chr20 | 50173348 | 50173354 | 7mer-m8 | 50173334 | 50173355 | 151 | -12.38 |
| ADediting_496066 | chr15_66496985_- | ENSG00000231742.6 | ENST00000411453.3 | LINC01273-201 | hsa-miR-4512 | chr20 | 50172555 | 50172561 | 7mer-m8 | 50172540 | 50172562 | 146 | -25.38 |
| ADediting_496066 | chr15_66496985_- | ENSG00000231742.6 | ENST00000427333.6 | LINC01273-202 | hsa-miR-4512 | chr20 | 50172555 | 50172561 | 7mer-m8 | 50172540 | 50172562 | 146 | -25.38 |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for LINC01273 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000427333.6 | lncRNA |  |  |
| ENST00000664618.1 | lncRNA |  |  |
| ENST00000661469.1 | lncRNA |  |  |
| ENST00000665536.1 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_943986 | ENST00000427333.6 | chr20_50173207_+ | 355 | -244.80 | -244.80 | -255.20 |
| ADediting_943987 | ENST00000427333.6 | chr20_50173250_+ | 398 | -244.40 | -244.80 | -255.20 |
| ADediting_943988 | ENST00000427333.6 | chr20_50173255_+ | 403 | -244.10 | -244.80 | -255.20 |
| ADediting_943989 | ENST00000427333.6 | chr20_50173293_+ | 441 | -245.70 | -244.80 | -255.20 |
| ADediting_943990 | ENST00000427333.6 | chr20_50173315_+ | 463 | -247.10 | -244.80 | -255.20 |
| ADediting_943991 | ENST00000427333.6 | chr20_50173317_+ | 465 | -245.40 | -244.80 | -255.20 |
| ADediting_943992 | ENST00000427333.6 | chr20_50173416_+ | 564 | -247.10 | -244.80 | -255.20 |
| ADediting_943993 | ENST00000427333.6 | chr20_50173443_+ | 591 | -251.40 | -244.80 | -255.20 |
| ADediting_943987 | ENST00000664618.1 | chr20_50173250_+ | 343 | -218.10 | -218.50 | -229.90 |
| ADediting_943988 | ENST00000664618.1 | chr20_50173255_+ | 348 | -217.80 | -218.50 | -229.90 |
| ADediting_943989 | ENST00000664618.1 | chr20_50173293_+ | 386 | -220.50 | -218.50 | -229.90 |
| ADediting_943990 | ENST00000664618.1 | chr20_50173315_+ | 408 | -219.60 | -218.50 | -229.90 |
| ADediting_943991 | ENST00000664618.1 | chr20_50173317_+ | 410 | -219.10 | -218.50 | -229.90 |
| ADediting_943992 | ENST00000664618.1 | chr20_50173416_+ | 509 | -220.70 | -218.50 | -229.90 |
| ADediting_943993 | ENST00000664618.1 | chr20_50173443_+ | 536 | -225.10 | -218.50 | -229.90 |
| ADediting_943986 | ENST00000661469.1 | chr20_50173207_+ | 323 | -303.30 | -302.10 | -307.70 |
| ADediting_943987 | ENST00000661469.1 | chr20_50173250_+ | 366 | -303.40 | -302.10 | -307.70 |
| ADediting_943988 | ENST00000661469.1 | chr20_50173255_+ | 371 | -301.40 | -302.10 | -307.70 |
| ADediting_943989 | ENST00000661469.1 | chr20_50173293_+ | 409 | -303.20 | -302.10 | -307.70 |
| ADediting_943990 | ENST00000661469.1 | chr20_50173315_+ | 431 | -303.30 | -302.10 | -307.70 |
| ADediting_943991 | ENST00000661469.1 | chr20_50173317_+ | 433 | -303.30 | -302.10 | -307.70 |
| ADediting_943985 | ENST00000665536.1 | chr20_50173200_+ | 472 | -271.80 | -271.00 | -281.70 |
| ADediting_943986 | ENST00000665536.1 | chr20_50173207_+ | 479 | -272.20 | -271.00 | -281.70 |
| ADediting_943987 | ENST00000665536.1 | chr20_50173250_+ | 522 | -270.60 | -271.00 | -281.70 |
| ADediting_943988 | ENST00000665536.1 | chr20_50173255_+ | 527 | -270.30 | -271.00 | -281.70 |
| ADediting_943989 | ENST00000665536.1 | chr20_50173293_+ | 565 | -270.70 | -271.00 | -281.70 |
| ADediting_943990 | ENST00000665536.1 | chr20_50173315_+ | 587 | -271.00 | -271.00 | -281.70 |
| ADediting_943991 | ENST00000665536.1 | chr20_50173317_+ | 589 | -271.60 | -271.00 | -281.70 |
| ADediting_943992 | ENST00000665536.1 | chr20_50173416_+ | 688 | -274.20 | -271.00 | -281.70 |
| ADediting_943993 | ENST00000665536.1 | chr20_50173443_+ | 715 | -273.50 | -271.00 | -281.70 |
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Relation with ADAR for LINC01273 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.51990666773828e-07 | 0.292809477737898 | 0.0118939218376101 | 0.142702705935744 | 5.67639818469096e-62 | 0.769643793868226 |
| AC | 1.01926362285734e-22 | 0.5675709934637 | 3.23738291999114e-10 | 0.384183660795081 | 2.35847749740404e-24 | 0.58502905361046 |
| STG | 0.401495107811962 | 0.0927293799790446 | 0.963838789024331 | 0.00502187651779766 | 0.000340058991343658 | 0.381712712197154 |
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Relation with AD stages for LINC01273 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for LINC01273 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LINC01273 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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