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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for CHURC1-FNTB

check button Gene summary
Gene informationGene symbol

CHURC1-FNTB

Gene ID

100529261

Gene nameCHURC1-FNTB readthrough
SynonymsFNTB|FTase-beta
Cytomap

14q23.3

Type of geneprotein-coding
DescriptionCHURC1-FNTB proteinCAAX farnesyltransferase subunit betaProtein farnesyltransferase subunit betaRas proteins prenyltransferase subunit beta
Modification date20200313
UniProtAcc

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for CHURC1-FNTB

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_440909(64916639, +), ADediting_440910(64916769, +), ADediting_440911(64916785, +), ADediting_440912(64917377, +), ADediting_440913(64917432, +), ADediting_440914(64917443, +), ADediting_440915(64917483, +), ADediting_440916(64917495, +), ADediting_440917(64917520, +), ADediting_440918(64925415, +), ADediting_440919(64925431, +), ADediting_440920(64925472, +), ADediting_440921(64925477, +), ADediting_440922(64925491, +), ADediting_440923(64925527, +), ADediting_440924(64925574, +), ADediting_440925(64925611, +), ADediting_440926(64925612, +), ADediting_440927(64925632, +), ADediting_440928(64926285, +), ADediting_440929(64926320, +), ADediting_440930(64927813, +), ADediting_440931(64927815, +), ADediting_440932(64928347, +), ADediting_440933(64931278, +), ADediting_440934(64931279, +), ADediting_440935(64931300, +), ADediting_440936(64931301, +), ADediting_440937(64931348, +), ADediting_440938(64931352, +), ADediting_440939(64931369, +), ADediting_440940(64931413, +), ADediting_440941(64931449, +), ADediting_440942(64931459, +), ADediting_440943(64934088, +), ADediting_440944(64934109, +), ADediting_440945(64934111, +), ADediting_440946(64934114, +), ADediting_440947(64934123, +), ADediting_440948(64934157, +), ADediting_440949(64934198, +), ADediting_440950(64934199, +), ADediting_440951(64934202, +), ADediting_440952(64934218, +), ADediting_440953(64934228, +), ADediting_440954(64934269, +), ADediting_440955(64934297, +), ADediting_440956(64934298, +), ADediting_440957(64936359, +), ADediting_440958(64936401, +), ADediting_440959(64936425, +), ADediting_440960(64936435, +), ADediting_440961(64936436, +), ADediting_440962(64936461, +), ADediting_440963(64936530, +), ADediting_440964(64936551, +), ADediting_440965(64936582, +), ADediting_440966(64936600, +), ADediting_440967(64936609, +), ADediting_440968(64936610, +), ADediting_440969(64938340, +), ADediting_440970(64938413, +), ADediting_440971(64938451, +), ADediting_440972(64938575, +), ADediting_440973(64945082, +), ADediting_440974(64945083, +), ADediting_440975(64973391, +), ADediting_440976(64974244, +), ADediting_440977(64974450, +), ADediting_440978(64974451, +), ADediting_440979(64974461, +), ADediting_440980(64975079, +), ADediting_440981(64975148, +), ADediting_440982(64975149, +), ADediting_440983(64975164, +), ADediting_440984(64975188, +), ADediting_440985(64975544, +), ADediting_440986(64975792, +), ADediting_440987(64975799, +), ADediting_440988(64975800, +), ADediting_440989(64975805, +), ADediting_440990(64975856, +), ADediting_440991(64975865, +), ADediting_440992(64976275, +), ADediting_440993(64976334, +), ADediting_440994(64976335, +), ADediting_440995(64976342, +), ADediting_440996(64976391, +), ADediting_440997(64976392, +), ADediting_440998(64977434, +), ADediting_440999(64977488, +), ADediting_441000(64977489, +), ADediting_441001(64977555, +), ADediting_441002(64977630, +), ADediting_441003(64977998, +), ADediting_441004(64980181, +), ADediting_441005(64980324, +), ADediting_441006(64988552, +), ADediting_441007(64988564, +), ADediting_441008(64988569, +), ADediting_441009(64988574, +), ADediting_441010(64988576, +), ADediting_441011(64988614, +), ADediting_441012(64988617, +), ADediting_441013(64988633, +), ADediting_441014(64988641, +), ADediting_441015(64988667, +), ADediting_441016(64988706, +), ADediting_441017(64989185, +), ADediting_441018(64989186, +), ADediting_441019(64989194, +), ADediting_441020(64989216, +), ADediting_441021(64989232, +), ADediting_441022(64989240, +), ADediting_441023(64989253, +), ADediting_441024(64989256, +), ADediting_441025(64989317, +), ADediting_441026(64989323, +), ADediting_441027(64989341, +), ADediting_441028(64991448, +), ADediting_441029(64991451, +), ADediting_441030(64991457, +), ADediting_441031(64991483, +), ADediting_441032(64991493, +), ADediting_441033(64995952, +), ADediting_441034(64996222, +), ADediting_441035(65001345, +), ADediting_441036(65001387, +), ADediting_441037(65004685, +), ADediting_441038(65004756, +), ADediting_441039(65004846, +), ADediting_1537335(64926282, +), ADediting_1537336(64934147, +), ADediting_1537337(64934254, +), ADediting_1537338(64934303, +), ADediting_1537339(64936418, +), ADediting_1537340(64936474, +), ADediting_1537341(64936622, +), ADediting_1537342(65001410, +), ADediting_1537343(65001433, +), ADediting_1619778(64993020, +),

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RNA editing positional annotations for CHURC1-FNTB using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_440909chr14_64916639_+intronic
ADediting_440910chr14_64916769_+intronic
ADediting_440911chr14_64916785_+intronic
ADediting_440912chr14_64917377_+intronic
ADediting_440913chr14_64917432_+intronic
ADediting_440914chr14_64917443_+intronic
ADediting_440915chr14_64917483_+intronic
ADediting_440916chr14_64917495_+intronic
ADediting_440917chr14_64917520_+intronic
ADediting_440918chr14_64925415_+intronic
ADediting_440919chr14_64925431_+intronic
ADediting_440920chr14_64925472_+intronic
ADediting_440921chr14_64925477_+intronic
ADediting_440922chr14_64925491_+intronic
ADediting_440923chr14_64925527_+intronic
ADediting_440924chr14_64925574_+intronic
ADediting_440925chr14_64925611_+intronic
ADediting_440926chr14_64925612_+intronic
ADediting_440927chr14_64925632_+intronic
ADediting_440928chr14_64926285_+intronic
ADediting_440929chr14_64926320_+intronic
ADediting_440930chr14_64927813_+intronic
ADediting_440931chr14_64927815_+intronic
ADediting_440932chr14_64928347_+intronic
ADediting_440933chr14_64931278_+intronic
ADediting_440934chr14_64931279_+intronic
ADediting_440935chr14_64931300_+intronic
ADediting_440936chr14_64931301_+intronic
ADediting_440937chr14_64931348_+intronic
ADediting_440938chr14_64931352_+intronic
ADediting_440939chr14_64931369_+intronic
ADediting_440940chr14_64931413_+intronic
ADediting_440941chr14_64931449_+intronic
ADediting_440942chr14_64931459_+intronic
ADediting_440943chr14_64934088_+UTR3
ADediting_440944chr14_64934109_+UTR3
ADediting_440945chr14_64934111_+UTR3
ADediting_440946chr14_64934114_+UTR3
ADediting_440947chr14_64934123_+UTR3
ADediting_440948chr14_64934157_+UTR3
ADediting_440949chr14_64934198_+UTR3
ADediting_440950chr14_64934199_+UTR3
ADediting_440951chr14_64934202_+UTR3
ADediting_440952chr14_64934218_+UTR3
ADediting_440953chr14_64934228_+UTR3
ADediting_440954chr14_64934269_+UTR3
ADediting_440955chr14_64934297_+UTR3
ADediting_440956chr14_64934298_+UTR3
ADediting_440957chr14_64936359_+intronic
ADediting_440958chr14_64936401_+intronic
ADediting_440959chr14_64936425_+intronic
ADediting_440960chr14_64936435_+intronic
ADediting_440961chr14_64936436_+intronic
ADediting_440962chr14_64936461_+intronic
ADediting_440963chr14_64936530_+intronic
ADediting_440964chr14_64936551_+intronic
ADediting_440965chr14_64936582_+intronic
ADediting_440966chr14_64936600_+intronic
ADediting_440967chr14_64936609_+intronic
ADediting_440968chr14_64936610_+intronic
ADediting_440969chr14_64938340_+intronic
ADediting_440970chr14_64938413_+intronic
ADediting_440971chr14_64938451_+intronic
ADediting_440972chr14_64938575_+intronic
ADediting_440973chr14_64945082_+intronic
ADediting_440974chr14_64945083_+intronic
ADediting_440975chr14_64973391_+intronic
ADediting_440976chr14_64974244_+intronic
ADediting_440977chr14_64974450_+intronic
ADediting_440978chr14_64974451_+intronic
ADediting_440979chr14_64974461_+intronic
ADediting_440980chr14_64975079_+intronic
ADediting_440981chr14_64975148_+intronic
ADediting_440982chr14_64975149_+intronic
ADediting_440983chr14_64975164_+intronic
ADediting_440984chr14_64975188_+intronic
ADediting_440985chr14_64975544_+intronic
ADediting_440986chr14_64975792_+intronic
ADediting_440987chr14_64975799_+intronic
ADediting_440988chr14_64975800_+intronic
ADediting_440989chr14_64975805_+intronic
ADediting_440990chr14_64975856_+intronic
ADediting_440991chr14_64975865_+intronic
ADediting_440992chr14_64976275_+intronic
ADediting_440993chr14_64976334_+intronic
ADediting_440994chr14_64976335_+intronic
ADediting_440995chr14_64976342_+intronic
ADediting_440996chr14_64976391_+intronic
ADediting_440997chr14_64976392_+intronic
ADediting_440998chr14_64977434_+intronic
ADediting_440999chr14_64977488_+intronic
ADediting_441000chr14_64977489_+intronic
ADediting_441001chr14_64977555_+intronic
ADediting_441002chr14_64977630_+intronic
ADediting_441003chr14_64977998_+intronic
ADediting_441004chr14_64980181_+intronic
ADediting_441005chr14_64980324_+intronic
ADediting_441006chr14_64988552_+intronic
ADediting_441007chr14_64988564_+intronic
ADediting_441008chr14_64988569_+intronic
ADediting_441009chr14_64988574_+intronic
ADediting_441010chr14_64988576_+intronic
ADediting_441011chr14_64988614_+intronic
ADediting_441012chr14_64988617_+intronic
ADediting_441013chr14_64988633_+intronic
ADediting_441014chr14_64988641_+intronic
ADediting_441015chr14_64988667_+intronic
ADediting_441016chr14_64988706_+intronic
ADediting_441017chr14_64989185_+intronic
ADediting_441018chr14_64989186_+intronic
ADediting_441019chr14_64989194_+intronic
ADediting_441020chr14_64989216_+intronic
ADediting_441021chr14_64989232_+intronic
ADediting_441022chr14_64989240_+intronic
ADediting_441023chr14_64989253_+intronic
ADediting_441024chr14_64989256_+intronic
ADediting_441025chr14_64989317_+intronic
ADediting_441026chr14_64989323_+intronic
ADediting_441027chr14_64989341_+intronic
ADediting_441028chr14_64991448_+intronic
ADediting_441029chr14_64991451_+intronic
ADediting_441030chr14_64991457_+intronic
ADediting_441031chr14_64991483_+intronic
ADediting_441032chr14_64991493_+intronic
ADediting_441033chr14_64995952_+intronic
ADediting_441034chr14_64996222_+intronic
ADediting_441035chr14_65001345_+intronic
ADediting_441036chr14_65001387_+intronic
ADediting_441037chr14_65004685_+intronic
ADediting_441038chr14_65004756_+intronic
ADediting_441039chr14_65004846_+intronic
ADediting_1537335chr14_64926282_+intronic
ADediting_1537336chr14_64934147_+UTR3
ADediting_1537337chr14_64934254_+UTR3
ADediting_1537338chr14_64934303_+UTR3
ADediting_1537339chr14_64936418_+intronic
ADediting_1537340chr14_64936474_+intronic
ADediting_1537341chr14_64936622_+intronic
ADediting_1537342chr14_65001410_+intronic
ADediting_1537343chr14_65001433_+intronic
ADediting_1619778chr14_64993020_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_440909chr14_64916639_+SINEAluName=AluY
ADediting_440910chr14_64916769_+SINEAluName=AluY
ADediting_440911chr14_64916785_+SINEAluName=AluY
ADediting_440912chr14_64917377_+SINEAluName=AluSq2
ADediting_440913chr14_64917432_+SINEAluName=AluSq2
ADediting_440914chr14_64917443_+SINEAluName=AluSq2
ADediting_440915chr14_64917483_+SINEAluName=AluSq2
ADediting_440916chr14_64917495_+SINEAluName=AluSq2
ADediting_440917chr14_64917520_+SINEAluName=AluSq2
ADediting_440918chr14_64925415_+SINEAluName=AluJb
ADediting_440919chr14_64925431_+SINEAluName=AluJb
ADediting_440920chr14_64925472_+SINEAluName=AluJb
ADediting_440921chr14_64925477_+SINEAluName=AluJb
ADediting_440922chr14_64925491_+SINEAluName=AluJb
ADediting_440923chr14_64925527_+SINEAluName=AluJb
ADediting_440924chr14_64925574_+SINEAluName=AluJb
ADediting_440925chr14_64925611_+SINEAluName=AluJb
ADediting_440926chr14_64925612_+SINEAluName=AluJb
ADediting_440927chr14_64925632_+SINEAluName=AluJb
ADediting_440928chr14_64926285_+SINEAluName=FLAM_C
ADediting_440929chr14_64926320_+SINEAluName=FLAM_C
ADediting_440930chr14_64927813_+SINEAluName=FLAM_A
ADediting_440931chr14_64927815_+SINEAluName=FLAM_A
ADediting_440932chr14_64928347_+SINEAluName=AluJb
ADediting_440933chr14_64931278_+SINEAluName=AluJb
ADediting_440934chr14_64931279_+SINEAluName=AluJb
ADediting_440935chr14_64931300_+SINEAluName=AluJb
ADediting_440936chr14_64931301_+SINEAluName=AluJb
ADediting_440937chr14_64931348_+SINEAluName=AluJb
ADediting_440938chr14_64931352_+SINEAluName=AluJb
ADediting_440939chr14_64931369_+SINEAluName=AluJb
ADediting_440940chr14_64931413_+SINEAluName=AluJb
ADediting_440941chr14_64931449_+SINEAluName=AluJb
ADediting_440942chr14_64931459_+SINEAluName=AluJb
ADediting_440943chr14_64934088_+SINEAluName=AluSx
ADediting_440944chr14_64934109_+SINEAluName=AluSx
ADediting_440945chr14_64934111_+SINEAluName=AluSx
ADediting_440946chr14_64934114_+SINEAluName=AluSx
ADediting_440947chr14_64934123_+SINEAluName=AluSx
ADediting_440948chr14_64934157_+SINEAluName=AluSx
ADediting_440949chr14_64934198_+SINEAluName=AluSx
ADediting_440950chr14_64934199_+SINEAluName=AluSx
ADediting_440951chr14_64934202_+SINEAluName=AluSx
ADediting_440952chr14_64934218_+SINEAluName=AluSx
ADediting_440953chr14_64934228_+SINEAluName=AluSx
ADediting_440954chr14_64934269_+SINEAluName=AluSx
ADediting_440955chr14_64934297_+SINEAluName=AluSx
ADediting_440956chr14_64934298_+SINEAluName=AluSx
ADediting_440957chr14_64936359_+SINEAluName=AluJo
ADediting_440958chr14_64936401_+SINEAluName=AluJo
ADediting_440959chr14_64936425_+SINEAluName=AluJo
ADediting_440960chr14_64936435_+SINEAluName=AluJo
ADediting_440961chr14_64936436_+SINEAluName=AluJo
ADediting_440962chr14_64936461_+SINEAluName=AluJo
ADediting_440963chr14_64936530_+SINEAluName=AluJo
ADediting_440964chr14_64936551_+SINEAluName=AluJo
ADediting_440965chr14_64936582_+SINEAluName=AluJo
ADediting_440966chr14_64936600_+SINEAluName=AluJo
ADediting_440967chr14_64936609_+SINEAluName=AluJo
ADediting_440968chr14_64936610_+SINEAluName=AluJo
ADediting_440969chr14_64938340_+SINEAluName=AluSz
ADediting_440970chr14_64938413_+SINEAluName=AluSz
ADediting_440971chr14_64938451_+SINEAluName=AluSz
ADediting_440972chr14_64938575_+SINEAluName=AluSz
ADediting_440973chr14_64945082_+SINEAluName=AluJo
ADediting_440974chr14_64945083_+SINEAluName=AluJo
ADediting_440975chr14_64973391_+SINEAluName=AluSz
ADediting_440976chr14_64974244_+SINEAluName=AluY
ADediting_440977chr14_64974450_+SINEAluName=AluY
ADediting_440978chr14_64974451_+SINEAluName=AluY
ADediting_440979chr14_64974461_+SINEAluName=AluY
ADediting_440980chr14_64975079_+SINEAluName=AluSq2
ADediting_440981chr14_64975148_+SINEAluName=AluSq2
ADediting_440982chr14_64975149_+SINEAluName=AluSq2
ADediting_440983chr14_64975164_+SINEAluName=AluSq2
ADediting_440984chr14_64975188_+SINEAluName=AluSq2
ADediting_440985chr14_64975544_+SINEAluName=AluSx1
ADediting_440986chr14_64975792_+SINEAluName=AluSg
ADediting_440987chr14_64975799_+SINEAluName=AluSg
ADediting_440988chr14_64975800_+SINEAluName=AluSg
ADediting_440989chr14_64975805_+SINEAluName=AluSg
ADediting_440990chr14_64975856_+SINEAluName=AluSg
ADediting_440991chr14_64975865_+SINEAluName=AluSg
ADediting_440992chr14_64976275_+SINEAluName=AluSx
ADediting_440993chr14_64976334_+SINEAluName=AluSx
ADediting_440994chr14_64976335_+SINEAluName=AluSx
ADediting_440995chr14_64976342_+SINEAluName=AluSx
ADediting_440996chr14_64976391_+SINEAluName=AluSx
ADediting_440997chr14_64976392_+SINEAluName=AluSx
ADediting_440998chr14_64977434_+SINEAluName=AluSg
ADediting_440999chr14_64977488_+SINEAluName=AluSg
ADediting_441000chr14_64977489_+SINEAluName=AluSg
ADediting_441001chr14_64977555_+SINEAluName=AluSg
ADediting_441002chr14_64977630_+SINEAluName=AluSg
ADediting_441003chr14_64977998_+SINEAluName=AluY
ADediting_441004chr14_64980181_+SINEAluName=AluSc
ADediting_441005chr14_64980324_+SINEAluName=AluSc
ADediting_441006chr14_64988552_+SINEAluName=AluSx1
ADediting_441007chr14_64988564_+SINEAluName=AluSx1
ADediting_441008chr14_64988569_+SINEAluName=AluSx1
ADediting_441009chr14_64988574_+SINEAluName=AluSx1
ADediting_441010chr14_64988576_+SINEAluName=AluSx1
ADediting_441011chr14_64988614_+SINEAluName=AluSx1
ADediting_441012chr14_64988617_+SINEAluName=AluSx1
ADediting_441013chr14_64988633_+SINEAluName=AluSx1
ADediting_441014chr14_64988641_+SINEAluName=AluSx1
ADediting_441015chr14_64988667_+SINEAluName=AluSx1
ADediting_441016chr14_64988706_+SINEAluName=AluSx1
ADediting_441017chr14_64989185_+SINEAluName=AluJo
ADediting_441018chr14_64989186_+SINEAluName=AluJo
ADediting_441019chr14_64989194_+SINEAluName=AluJo
ADediting_441020chr14_64989216_+SINEAluName=AluJo
ADediting_441021chr14_64989232_+SINEAluName=AluJo
ADediting_441022chr14_64989240_+SINEAluName=AluJo
ADediting_441023chr14_64989253_+SINEAluName=AluJo
ADediting_441024chr14_64989256_+SINEAluName=AluJo
ADediting_441025chr14_64989317_+SINEAluName=AluJo
ADediting_441026chr14_64989323_+SINEAluName=AluJo
ADediting_441027chr14_64989341_+SINEAluName=AluJo
ADediting_441028chr14_64991448_+SINEAluName=AluSz
ADediting_441029chr14_64991451_+SINEAluName=AluSz
ADediting_441030chr14_64991457_+SINEAluName=AluSz
ADediting_441031chr14_64991483_+SINEAluName=AluSz
ADediting_441032chr14_64991493_+SINEAluName=AluSz
ADediting_441033chr14_64995952_+SINEAluName=AluSq2
ADediting_441034chr14_64996222_+SINEAluName=FLAM_C
ADediting_441035chr14_65001345_+DNATcMar-TiggerName=Tigger3a
ADediting_441036chr14_65001387_+DNATcMar-TiggerName=Tigger3a
ADediting_441037chr14_65004685_+SINEAluName=AluSq
ADediting_441038chr14_65004756_+SINEAluName=AluSq
ADediting_441039chr14_65004846_+SINEAluName=AluSq
ADediting_1537335chr14_64926282_+SINEAluName=FLAM_C
ADediting_1537336chr14_64934147_+SINEAluName=AluSx
ADediting_1537337chr14_64934254_+SINEAluName=AluSx
ADediting_1537338chr14_64934303_+SINEAluName=AluSx
ADediting_1537339chr14_64936418_+SINEAluName=AluJo
ADediting_1537340chr14_64936474_+SINEAluName=AluJo
ADediting_1537341chr14_64936622_+SINEAluName=AluJo
ADediting_1537342chr14_65001410_+DNATcMar-TiggerName=Tigger3a
ADediting_1537343chr14_65001433_+DNATcMar-TiggerName=Tigger3a
ADediting_1619778chr14_64993020_+SINEAluName=AluJb

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RNA A-to-I editing events in the alternative splicing sites for CHURC1-FNTB

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CHURC1-FNTB

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for CHURC1-FNTB

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for CHURC1-FNTB


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CHURC1-FNTB

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for CHURC1-FNTB

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_440976chr14_64974244_+0.3289520644185880.05562773757949590.247782686022414-0.06583701689394969.71653217524586e-230.518594357240536
DLPFCADediting_440977chr14_64974450_+0.1528755004348380.08138123280761880.685512697718686-0.02308994655530896.30520638360933e-100.341891688401098
DLPFCADediting_440988chr14_64975800_+0.7171520554777080.02065667027652150.0558967952817566-0.1087023476047042.36674874701743e-210.50374831745009

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC3.88372022822437e-060.2588202591361940.3586225265145180.05231412495186234.2207083746318e-100.345162012708016
AC8.88298801092232e-090.35366186504753.62117192881668e-060.288160917614630.0006166331197790.215102253957114
CER3.08937682461629e-110.5084346087402387.255308678122e-060.357120376870980.003553002737670870.236626029829912
TCX9.68261078732472e-090.4471409381828570.4123675580216860.0674188228496961.61153995990532e-090.467593538283945
PG3.65698272923884e-110.4607448769879230.0001842455664314990.2708888704231620.1447104960102980.107354760666189
STG0.003023750052054170.31979213895120.02667871925585790.2418281784071060.003279591061338980.317229666930116

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Relation with AD stages for CHURC1-FNTB

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
TCX0.001191034759962940.310652289032902

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RelatedDrugs for CHURC1-FNTB

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CHURC1-FNTB

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource