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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for CKLF-CMTM1 |
 Gene summary |
| Gene information | Gene symbol | CKLF-CMTM1 | Gene ID | 100529251 |
| Gene name | CKLF-CMTM1 readthrough | |
| Synonyms | - | |
| Cytomap | 16q21 | |
| Type of gene | protein-coding | |
| Description | CKLF-CMTM1 protein | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for CKLF-CMTM1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_551719(66553031, +), ADediting_551720(66553033, +), ADediting_551721(66553085, +), ADediting_551722(66553135, +), ADediting_551723(66554980, +), ADediting_551724(66554981, +), ADediting_551725(66554994, +), ADediting_551726(66555002, +), ADediting_551727(66555003, +), ADediting_551728(66555007, +), ADediting_551729(66555026, +), ADediting_551730(66555047, +), ADediting_551731(66555048, +), ADediting_551732(66555063, +), ADediting_551733(66555072, +), ADediting_551734(66555116, +), ADediting_551735(66555117, +), ADediting_551736(66555122, +), ADediting_551737(66555126, +), ADediting_551738(66555143, +), ADediting_551739(66555152, +), ADediting_551740(66555169, +), ADediting_551741(66555181, +), ADediting_551742(66555188, +), ADediting_551743(66555192, +), ADediting_551744(66555219, +), ADediting_551745(66555220, +), ADediting_551746(66555221, +), ADediting_551747(66557190, +), ADediting_551748(66557194, +), ADediting_551749(66557201, +), ADediting_551750(66557207, +), ADediting_551751(66557267, +), ADediting_551752(66557268, +), ADediting_551753(66557285, +), ADediting_551754(66557297, +), ADediting_551755(66557307, +), ADediting_551756(66557348, +), ADediting_551757(66557351, +), ADediting_551758(66557357, +), ADediting_551759(66557358, +), ADediting_551760(66557402, +), ADediting_551761(66557428, +), ADediting_551762(66557429, +), ADediting_551763(66557442, +), ADediting_551764(66558017, +), ADediting_551765(66558036, +), ADediting_551766(66558055, +), ADediting_551767(66558060, +), ADediting_551768(66558071, +), ADediting_551769(66558088, +), ADediting_551770(66562149, +), ADediting_551771(66562188, +), ADediting_551772(66562189, +), ADediting_551773(66562214, +), ADediting_551774(66562224, +), ADediting_551775(66562266, +), ADediting_551776(66562267, +), ADediting_551777(66562269, +), ADediting_551778(66562270, +), ADediting_551779(66562275, +), ADediting_551780(66562795, +), ADediting_551781(66562801, +), ADediting_551782(66562860, +), ADediting_551783(66562905, +), ADediting_551784(66562942, +), ADediting_551785(66564610, +), ADediting_551786(66568615, +), ADediting_551787(66568684, +), ADediting_551788(66568685, +), ADediting_551789(66568699, +), ADediting_551790(66568710, +), ADediting_551791(66568739, +), ADediting_551792(66568749, +), ADediting_551793(66568765, +), ADediting_551794(66568792, +), ADediting_551795(66568811, +), ADediting_551796(66568815, +), ADediting_1543325(66554989, +), ADediting_1543326(66555073, +), ADediting_1543327(66555078, +), ADediting_1543328(66555186, +), ADediting_1543329(66557309, +), ADediting_1543330(66558042, +), ADediting_1543331(66558043, +), ADediting_1543332(66558070, +), ADediting_1543333(66562226, +), ADediting_1543334(66562259, +), ADediting_1543335(66562838, +), ADediting_1543336(66562977, +), ADediting_1543337(66564652, +), ADediting_1543338(66568653, +), ADediting_1543339(66568662, +), ADediting_1543340(66568818, +), |
Top |
RNA editing positional annotations for CKLF-CMTM1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_551719 | chr16_66553031_+ | intronic |
| ADediting_551720 | chr16_66553033_+ | intronic |
| ADediting_551721 | chr16_66553085_+ | intronic |
| ADediting_551722 | chr16_66553135_+ | intronic |
| ADediting_551723 | chr16_66554980_+ | intronic |
| ADediting_551724 | chr16_66554981_+ | intronic |
| ADediting_551725 | chr16_66554994_+ | intronic |
| ADediting_551726 | chr16_66555002_+ | intronic |
| ADediting_551727 | chr16_66555003_+ | intronic |
| ADediting_551728 | chr16_66555007_+ | intronic |
| ADediting_551729 | chr16_66555026_+ | intronic |
| ADediting_551730 | chr16_66555047_+ | intronic |
| ADediting_551731 | chr16_66555048_+ | intronic |
| ADediting_551732 | chr16_66555063_+ | intronic |
| ADediting_551733 | chr16_66555072_+ | intronic |
| ADediting_551734 | chr16_66555116_+ | intronic |
| ADediting_551735 | chr16_66555117_+ | intronic |
| ADediting_551736 | chr16_66555122_+ | intronic |
| ADediting_551737 | chr16_66555126_+ | intronic |
| ADediting_551738 | chr16_66555143_+ | intronic |
| ADediting_551739 | chr16_66555152_+ | intronic |
| ADediting_551740 | chr16_66555169_+ | intronic |
| ADediting_551741 | chr16_66555181_+ | intronic |
| ADediting_551742 | chr16_66555188_+ | intronic |
| ADediting_551743 | chr16_66555192_+ | intronic |
| ADediting_551744 | chr16_66555219_+ | intronic |
| ADediting_551745 | chr16_66555220_+ | intronic |
| ADediting_551746 | chr16_66555221_+ | intronic |
| ADediting_551747 | chr16_66557190_+ | intronic |
| ADediting_551748 | chr16_66557194_+ | intronic |
| ADediting_551749 | chr16_66557201_+ | intronic |
| ADediting_551750 | chr16_66557207_+ | intronic |
| ADediting_551751 | chr16_66557267_+ | intronic |
| ADediting_551752 | chr16_66557268_+ | intronic |
| ADediting_551753 | chr16_66557285_+ | intronic |
| ADediting_551754 | chr16_66557297_+ | intronic |
| ADediting_551755 | chr16_66557307_+ | intronic |
| ADediting_551756 | chr16_66557348_+ | intronic |
| ADediting_551757 | chr16_66557351_+ | intronic |
| ADediting_551758 | chr16_66557357_+ | intronic |
| ADediting_551759 | chr16_66557358_+ | intronic |
| ADediting_551760 | chr16_66557402_+ | intronic |
| ADediting_551761 | chr16_66557428_+ | intronic |
| ADediting_551762 | chr16_66557429_+ | intronic |
| ADediting_551763 | chr16_66557442_+ | intronic |
| ADediting_551764 | chr16_66558017_+ | intronic |
| ADediting_551765 | chr16_66558036_+ | intronic |
| ADediting_551766 | chr16_66558055_+ | intronic |
| ADediting_551767 | chr16_66558060_+ | intronic |
| ADediting_551768 | chr16_66558071_+ | intronic |
| ADediting_551769 | chr16_66558088_+ | intronic |
| ADediting_551770 | chr16_66562149_+ | intronic |
| ADediting_551771 | chr16_66562188_+ | intronic |
| ADediting_551772 | chr16_66562189_+ | intronic |
| ADediting_551773 | chr16_66562214_+ | intronic |
| ADediting_551774 | chr16_66562224_+ | intronic |
| ADediting_551775 | chr16_66562266_+ | intronic |
| ADediting_551776 | chr16_66562267_+ | intronic |
| ADediting_551777 | chr16_66562269_+ | intronic |
| ADediting_551778 | chr16_66562270_+ | intronic |
| ADediting_551779 | chr16_66562275_+ | intronic |
| ADediting_551780 | chr16_66562795_+ | intronic |
| ADediting_551781 | chr16_66562801_+ | intronic |
| ADediting_551782 | chr16_66562860_+ | intronic |
| ADediting_551783 | chr16_66562905_+ | intronic |
| ADediting_551784 | chr16_66562942_+ | intronic |
| ADediting_551785 | chr16_66564610_+ | intronic |
| ADediting_551786 | chr16_66568615_+ | intronic |
| ADediting_551787 | chr16_66568684_+ | intronic |
| ADediting_551788 | chr16_66568685_+ | intronic |
| ADediting_551789 | chr16_66568699_+ | intronic |
| ADediting_551790 | chr16_66568710_+ | intronic |
| ADediting_551791 | chr16_66568739_+ | intronic |
| ADediting_551792 | chr16_66568749_+ | intronic |
| ADediting_551793 | chr16_66568765_+ | intronic |
| ADediting_551794 | chr16_66568792_+ | intronic |
| ADediting_551795 | chr16_66568811_+ | intronic |
| ADediting_551796 | chr16_66568815_+ | intronic |
| ADediting_1543325 | chr16_66554989_+ | intronic |
| ADediting_1543326 | chr16_66555073_+ | intronic |
| ADediting_1543327 | chr16_66555078_+ | intronic |
| ADediting_1543328 | chr16_66555186_+ | intronic |
| ADediting_1543329 | chr16_66557309_+ | intronic |
| ADediting_1543330 | chr16_66558042_+ | intronic |
| ADediting_1543331 | chr16_66558043_+ | intronic |
| ADediting_1543332 | chr16_66558070_+ | intronic |
| ADediting_1543333 | chr16_66562226_+ | intronic |
| ADediting_1543334 | chr16_66562259_+ | intronic |
| ADediting_1543335 | chr16_66562838_+ | intronic |
| ADediting_1543336 | chr16_66562977_+ | intronic |
| ADediting_1543337 | chr16_66564652_+ | intronic |
| ADediting_1543338 | chr16_66568653_+ | intronic |
| ADediting_1543339 | chr16_66568662_+ | intronic |
| ADediting_1543340 | chr16_66568818_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_551719 | chr16_66553031_+ | SINE | Alu | Name=FRAM |
| ADediting_551720 | chr16_66553033_+ | SINE | Alu | Name=FRAM |
| ADediting_551721 | chr16_66553085_+ | SINE | Alu | Name=FRAM |
| ADediting_551722 | chr16_66553135_+ | SINE | Alu | Name=FRAM |
| ADediting_551723 | chr16_66554980_+ | SINE | Alu | Name=AluSz |
| ADediting_551724 | chr16_66554981_+ | SINE | Alu | Name=AluSz |
| ADediting_551725 | chr16_66554994_+ | SINE | Alu | Name=AluSz |
| ADediting_551726 | chr16_66555002_+ | SINE | Alu | Name=AluSz |
| ADediting_551727 | chr16_66555003_+ | SINE | Alu | Name=AluSz |
| ADediting_551728 | chr16_66555007_+ | SINE | Alu | Name=AluSz |
| ADediting_551729 | chr16_66555026_+ | SINE | Alu | Name=AluSz |
| ADediting_551730 | chr16_66555047_+ | SINE | Alu | Name=AluSz |
| ADediting_551731 | chr16_66555048_+ | SINE | Alu | Name=AluSz |
| ADediting_551732 | chr16_66555063_+ | SINE | Alu | Name=AluSz |
| ADediting_551733 | chr16_66555072_+ | SINE | Alu | Name=AluSz |
| ADediting_551734 | chr16_66555116_+ | SINE | Alu | Name=AluSz |
| ADediting_551735 | chr16_66555117_+ | SINE | Alu | Name=AluSz |
| ADediting_551736 | chr16_66555122_+ | SINE | Alu | Name=AluSz |
| ADediting_551737 | chr16_66555126_+ | SINE | Alu | Name=AluSz |
| ADediting_551738 | chr16_66555143_+ | SINE | Alu | Name=AluSz |
| ADediting_551739 | chr16_66555152_+ | SINE | Alu | Name=AluSz |
| ADediting_551740 | chr16_66555169_+ | SINE | Alu | Name=AluSz |
| ADediting_551741 | chr16_66555181_+ | SINE | Alu | Name=AluSz |
| ADediting_551742 | chr16_66555188_+ | SINE | Alu | Name=AluSz |
| ADediting_551743 | chr16_66555192_+ | SINE | Alu | Name=AluSz |
| ADediting_551744 | chr16_66555219_+ | SINE | Alu | Name=AluSz |
| ADediting_551745 | chr16_66555220_+ | SINE | Alu | Name=AluSz |
| ADediting_551746 | chr16_66555221_+ | SINE | Alu | Name=AluSz |
| ADediting_551747 | chr16_66557190_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551748 | chr16_66557194_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551749 | chr16_66557201_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551750 | chr16_66557207_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551751 | chr16_66557267_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551752 | chr16_66557268_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551753 | chr16_66557285_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551754 | chr16_66557297_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551755 | chr16_66557307_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551756 | chr16_66557348_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551757 | chr16_66557351_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551758 | chr16_66557357_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551759 | chr16_66557358_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551760 | chr16_66557402_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551761 | chr16_66557428_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551762 | chr16_66557429_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551763 | chr16_66557442_+ | SINE | Alu | Name=AluSx1 |
| ADediting_551764 | chr16_66558017_+ | SINE | Alu | Name=FLAM_C |
| ADediting_551765 | chr16_66558036_+ | SINE | Alu | Name=FLAM_C |
| ADediting_551766 | chr16_66558055_+ | SINE | Alu | Name=FLAM_C |
| ADediting_551767 | chr16_66558060_+ | SINE | Alu | Name=FLAM_C |
| ADediting_551768 | chr16_66558071_+ | SINE | Alu | Name=FLAM_C |
| ADediting_551769 | chr16_66558088_+ | SINE | Alu | Name=FLAM_C |
| ADediting_551770 | chr16_66562149_+ | SINE | Alu | Name=AluSg |
| ADediting_551771 | chr16_66562188_+ | SINE | Alu | Name=AluSg |
| ADediting_551772 | chr16_66562189_+ | SINE | Alu | Name=AluSg |
| ADediting_551773 | chr16_66562214_+ | SINE | Alu | Name=AluSg |
| ADediting_551774 | chr16_66562224_+ | SINE | Alu | Name=AluSg |
| ADediting_551775 | chr16_66562266_+ | SINE | Alu | Name=AluSg |
| ADediting_551776 | chr16_66562267_+ | SINE | Alu | Name=AluSg |
| ADediting_551777 | chr16_66562269_+ | SINE | Alu | Name=AluSg |
| ADediting_551778 | chr16_66562270_+ | SINE | Alu | Name=AluSg |
| ADediting_551779 | chr16_66562275_+ | SINE | Alu | Name=AluSg |
| ADediting_551780 | chr16_66562795_+ | SINE | Alu | Name=AluSz6 |
| ADediting_551781 | chr16_66562801_+ | SINE | Alu | Name=AluSz6 |
| ADediting_551782 | chr16_66562860_+ | SINE | Alu | Name=AluSz6 |
| ADediting_551783 | chr16_66562905_+ | SINE | Alu | Name=AluSz6 |
| ADediting_551784 | chr16_66562942_+ | SINE | Alu | Name=AluSz6 |
| ADediting_551785 | chr16_66564610_+ | SINE | Alu | Name=AluY |
| ADediting_551786 | chr16_66568615_+ | SINE | Alu | Name=AluSx |
| ADediting_551787 | chr16_66568684_+ | SINE | Alu | Name=AluSx |
| ADediting_551788 | chr16_66568685_+ | SINE | Alu | Name=AluSx |
| ADediting_551789 | chr16_66568699_+ | SINE | Alu | Name=AluSx |
| ADediting_551790 | chr16_66568710_+ | SINE | Alu | Name=AluSx |
| ADediting_551791 | chr16_66568739_+ | SINE | Alu | Name=AluSx |
| ADediting_551792 | chr16_66568749_+ | SINE | Alu | Name=AluSx |
| ADediting_551793 | chr16_66568765_+ | SINE | Alu | Name=AluSx |
| ADediting_551794 | chr16_66568792_+ | SINE | Alu | Name=AluSx |
| ADediting_551795 | chr16_66568811_+ | SINE | Alu | Name=AluSx |
| ADediting_551796 | chr16_66568815_+ | SINE | Alu | Name=AluSx |
| ADediting_1543325 | chr16_66554989_+ | SINE | Alu | Name=AluSz |
| ADediting_1543326 | chr16_66555073_+ | SINE | Alu | Name=AluSz |
| ADediting_1543327 | chr16_66555078_+ | SINE | Alu | Name=AluSz |
| ADediting_1543328 | chr16_66555186_+ | SINE | Alu | Name=AluSz |
| ADediting_1543329 | chr16_66557309_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1543330 | chr16_66558042_+ | SINE | Alu | Name=FLAM_C |
| ADediting_1543331 | chr16_66558043_+ | SINE | Alu | Name=FLAM_C |
| ADediting_1543332 | chr16_66558070_+ | SINE | Alu | Name=FLAM_C |
| ADediting_1543333 | chr16_66562226_+ | SINE | Alu | Name=AluSg |
| ADediting_1543334 | chr16_66562259_+ | SINE | Alu | Name=AluSg |
| ADediting_1543335 | chr16_66562838_+ | SINE | Alu | Name=AluSz6 |
| ADediting_1543336 | chr16_66562977_+ | SINE | Alu | Name=AluSz6 |
| ADediting_1543337 | chr16_66564652_+ | SINE | Alu | Name=AluY |
| ADediting_1543338 | chr16_66568653_+ | SINE | Alu | Name=AluSx |
| ADediting_1543339 | chr16_66568662_+ | SINE | Alu | Name=AluSx |
| ADediting_1543340 | chr16_66568818_+ | SINE | Alu | Name=AluSx |
Top |
RNA A-to-I editing events in the alternative splicing sites for CKLF-CMTM1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for CKLF-CMTM1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for CKLF-CMTM1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for CKLF-CMTM1 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_291761 | chr11_93733708_- | ENSG00000254788.7 | ENST00000532838.1 | CKLF-CMTM1-204 | hsa-miR-1304-3p | chr16 | 66566387 | 66566394 | 8mer-1a | 66566373 | 66566394 | 153 | -24.04 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_527135 | chr16_24203190_+ | ENSG00000254788.7 | ENST00000532838.1 | CKLF-CMTM1-204 | hsa-miR-1273h-3p | chr16 | 66566125 | 66566131 | 7mer-m8 | 66566109 | 66566132 | 148 | -16.66 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000254788.7 | ENST00000527729.5 | CKLF-CMTM1-201 | hsa-miR-4775 | chr16 | 66579106 | 66579112 | 7mer-m8 | 66579091 | 66579113 | 151 | -12.16 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000254788.7 | ENST00000529718.1 | CKLF-CMTM1-203 | hsa-miR-4775 | chr16 | 66579106 | 66579112 | 7mer-m8 | 66579091 | 66579113 | 151 | -12.16 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000254788.7 | ENST00000616804.5 | CKLF-CMTM1-206 | hsa-miR-4775 | chr16 | 66579106 | 66579112 | 7mer-m8 | 66579091 | 66579113 | 151 | -12.16 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for CKLF-CMTM1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for CKLF-CMTM1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_551720 | chr16_66553033_+ | 0.00319963835846822 | 0.239190252146549 | 4.52753877657055e-06 | 0.364496656041106 | 1.07291947253072e-05 | 0.350857956969947 |
| CER | ADediting_551721 | chr16_66553085_+ | 0.00272514027978862 | 0.243068871710979 | 1.43171461328129e-08 | 0.442494984981198 | 0.0387056780758295 | 0.168992225357162 |
| CER | ADediting_551722 | chr16_66553135_+ | 0.00413475778163633 | 0.232866460015158 | 2.61630427040393e-05 | 0.336070330400213 | 0.0783960379468486 | 0.144163383961135 |
| CER | ADediting_551724 | chr16_66554981_+ | 0.00572205632532979 | 0.224610951645976 | 3.95601655859168e-05 | 0.328946945268156 | 0.137840183226081 | 0.121725752691586 |
| DLPFC | ADediting_551725 | chr16_66554994_+ | 0.0829045243067417 | 0.0986470795912153 | 0.888111729373266 | 0.0080231620935434 | 1.85200315979675e-08 | 0.312710007799498 |
| CER | ADediting_551725 | chr16_66554994_+ | 0.0124741108776422 | 0.20355913190677 | 3.23687390703587e-06 | 0.369636754764373 | 0.00681886900370244 | 0.22003486814956 |
| CER | ADediting_551726 | chr16_66555002_+ | 0.00027233676950063 | 0.293124047918658 | 9.2895348314284e-08 | 0.419265069905819 | 0.00348024160791869 | 0.237134625241807 |
| DLPFC | ADediting_551727 | chr16_66555003_+ | 0.0510076188989143 | 0.110938786885912 | 0.844105007878969 | 0.0112136598558666 | 2.38226366588041e-11 | 0.367545600089907 |
| CER | ADediting_551727 | chr16_66555003_+ | 0.00280212691264594 | 0.242400018819578 | 4.44173634238841e-06 | 0.364792118356855 | 0.0734834286157922 | 0.146573738135701 |
| CER | ADediting_551728 | chr16_66555007_+ | 0.00175334204242468 | 0.253426936143591 | 6.16755138053101e-06 | 0.35968193762299 | 0.00340839516745547 | 0.237646313816462 |
| DLPFC | ADediting_551731 | chr16_66555048_+ | 0.0906148584708789 | 0.0962739711802189 | 0.617310847988567 | 0.0284884011226515 | 3.45375253604235e-08 | 0.306971797009438 |
| DLPFC | ADediting_551732 | chr16_66555063_+ | 0.0249389668050493 | 0.127352221923998 | 0.969483514082507 | 0.00218160951652636 | 5.43160855406558e-17 | 0.45170101767102 |
| CER | ADediting_551734 | chr16_66555116_+ | 0.00552250750110597 | 0.225526690991068 | 0.000126251575202095 | 0.307951194884229 | 0.0331506973296894 | 0.174060555548449 |
| CER | ADediting_551735 | chr16_66555117_+ | 0.00575254591508982 | 0.224473552458103 | 0.000181921024106842 | 0.301004545620975 | 0.0701043642358657 | 0.148308506550978 |
| DLPFC | ADediting_551737 | chr16_66555126_+ | 0.252463435888393 | 0.0651909731592374 | 0.3650530925189 | -0.0516189865306878 | 3.98812325814119e-11 | 0.363659563322224 |
| CER | ADediting_551737 | chr16_66555126_+ | 0.015454178132332 | 0.197420827814632 | 0.000113305580537742 | 0.309975827211214 | 0.13322075619088 | 0.123161761588793 |
| DLPFC | ADediting_551739 | chr16_66555152_+ | 0.060104099010132 | 0.106904164864312 | 0.706607116791361 | -0.0214632765001006 | 2.70556883325251e-11 | 0.366590673662548 |
| CER | ADediting_551739 | chr16_66555152_+ | 0.00306741109689693 | 0.240215890090269 | 7.28156613917452e-06 | 0.357063154433913 | 0.111101635448788 | 0.130623938852563 |
| CER | ADediting_551740 | chr16_66555169_+ | 0.000562745108655495 | 0.278348747585873 | 9.41449041985183e-08 | 0.41909264167164 | 0.0846473147034286 | 0.141266212274167 |
| CER | ADediting_551741 | chr16_66555181_+ | 0.000977079545350497 | 0.266545104970726 | 7.47748332092669e-07 | 0.391105464086761 | 0.879799259583471 | -0.0124510433205592 |
| CER | ADediting_551742 | chr16_66555188_+ | 0.00370582051257306 | 0.235587679044099 | 1.04259279910611e-05 | 0.351321456238996 | 0.00761804257096841 | 0.217096985560711 |
| DLPFC | ADediting_551744 | chr16_66555219_+ | 0.0010589985145504 | 0.185109456859069 | 0.0902642906295707 | 0.0963782824051262 | 5.87644044992340e-09 | 0.322971145045306 |
| DLPFC | ADediting_551745 | chr16_66555220_+ | 0.000307911851269225 | 0.203623210231986 | 0.0486572414007551 | 0.112078105767665 | 4.03911465061909e-10 | 0.3455180410496 |
| CER | ADediting_551745 | chr16_66555220_+ | 9.62976271035598e-06 | 0.352601776197115 | 5.06352632713664e-10 | 0.480117331897924 | 0.106985781374528 | 0.132137931079509 |
| TCX | ADediting_551745 | chr16_66555220_+ | 0.110896282361864 | 0.130698427557976 | 0.408835312125998 | -0.0679284358244982 | 8.46581743855334e-06 | 0.354666310142341 |
| CER | ADediting_551748 | chr16_66557194_+ | 4.6390127835812e-05 | 0.326155441712948 | 8.86227006243336e-10 | 0.474125249282728 | 0.0155255626770652 | 0.19728693348669 |
| DLPFC | ADediting_551750 | chr16_66557207_+ | 0.0787641542898866 | 0.0999957101954352 | 0.667034888370938 | 0.0245303299663095 | 1.80951065109427e-11 | 0.369598388371924 |
| CER | ADediting_551750 | chr16_66557207_+ | 9.09256334721895e-07 | 0.388326849415679 | 2.24130959657231e-13 | 0.552729443889808 | 0.017279770803059 | 0.194154087570583 |
| CER | ADediting_551752 | chr16_66557268_+ | 0.000735473232355789 | 0.272687633616788 | 1.23925641003461e-07 | 0.415524220496 | 0.124306988886793 | 0.126044351059052 |
| CER | ADediting_551754 | chr16_66557297_+ | 0.00015094960017928 | 0.304575162896143 | 2.36821633962362e-09 | 0.463314895059145 | 0.0178808775159284 | 0.193144030118334 |
| CER | ADediting_551755 | chr16_66557307_+ | 0.00213782655165297 | 0.248822419310709 | 3.43353807909516e-07 | 0.401919324818199 | 0.292734529483457 | 0.086469348634471 |
| CER | ADediting_551756 | chr16_66557348_+ | 0.0154759414600487 | 0.197379949860458 | 2.89175685629001e-05 | 0.334361813484581 | 0.462572115824526 | 0.060432007272651 |
| DLPFC | ADediting_551760 | chr16_66557402_+ | 0.00716442800997086 | 0.152452896699688 | 0.812882179161237 | 0.0134981116878403 | 1.70510265887443e-19 | 0.482652219536443 |
| CER | ADediting_551760 | chr16_66557402_+ | 0.0080160622714963 | 0.215734624290237 | 3.69147316013156e-05 | 0.330151659447945 | 0.0298867603216371 | 0.177384731260441 |
| CER | ADediting_551763 | chr16_66557442_+ | 0.00250721806197314 | 0.245059313583112 | 2.5191561935482e-07 | 0.406117628780584 | 0.00336469436649491 | 0.23796232401963 |
| CER | ADediting_551765 | chr16_66558036_+ | 0.00114049504160663 | 0.263139472979928 | 7.92125951168123e-06 | 0.355726218900354 | 0.280747045999175 | 0.0886388287083594 |
| CER | ADediting_551766 | chr16_66558055_+ | 8.27776442992502e-05 | 0.315769531984283 | 1.63702045334368e-08 | 0.440887081683013 | 0.0862877573271381 | 0.140534468187526 |
| CER | ADediting_551767 | chr16_66558060_+ | 6.10341152359736e-06 | 0.359846043372049 | 2.10426423033004e-08 | 0.437851684405856 | 0.0883468655231241 | 0.139631549884053 |
| CER | ADediting_551768 | chr16_66558071_+ | 0.00568649193124561 | 0.224772048270215 | 6.35154591307789e-05 | 0.320567233900463 | 0.823870439455849 | 0.018324505031005 |
| CER | ADediting_551771 | chr16_66562188_+ | 0.00803989125315552 | 0.215654978399576 | 4.13860809198882e-06 | 0.365881150841227 | 0.0313341466058903 | 0.175874415470552 |
| CER | ADediting_551773 | chr16_66562214_+ | 0.189591107111375 | 0.107696308765386 | 7.80703550911199e-05 | 0.316837019210326 | 0.105059403665461 | 0.132862268774882 |
| CER | ADediting_551776 | chr16_66562267_+ | 0.00422969550275993 | 0.232298635795309 | 1.43289266759073e-05 | 0.346139842407323 | 0.16046762491138 | 0.115177109736801 |
| CER | ADediting_551778 | chr16_66562270_+ | 0.00635609959963646 | 0.221879274793386 | 3.85108543007215e-08 | 0.430420917559159 | 0.0439378504020442 | 0.164750581687684 |
| CER | ADediting_551779 | chr16_66562275_+ | 0.00131468912272113 | 0.2599696265993 | 1.27622552056141e-08 | 0.443867828449501 | 0.145607028927593 | 0.119391945954931 |
| CER | ADediting_551781 | chr16_66562801_+ | 2.78612753263688e-05 | 0.334998112451769 | 1.11049516112774e-09 | 0.471677230636177 | 0.0108226597977659 | 0.207539312738237 |
| CER | ADediting_551784 | chr16_66562942_+ | 0.000822362812060889 | 0.270289915689692 | 6.08867040443201e-08 | 0.424667693795807 | 0.0184104814887312 | 0.192278234699938 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 4.01658745128035e-13 | 0.396634448102841 | 6.08985480076075e-21 | 0.499210989750645 | 0.000426273660565066 | 0.198908072670114 |
| AC | 1.65035086797534e-32 | 0.658905424832076 | 4.20436447295618e-36 | 0.685942456219094 | 0.000479524177876925 | 0.219255218489485 |
| PCC | 9.82377179556479e-30 | 0.702536328981514 | 6.28262378401768e-31 | 0.71274611366254 | 0.562343625043111 | 0.0421795198951222 |
| CER | 4.90037876620225e-14 | 0.565186541042417 | 3.35355320017133e-18 | 0.633454805283384 | 0.000238158132060051 | 0.295768465952414 |
| TCX | 1.71055214692478e-09 | 0.466934645409256 | 2.1882991161998e-06 | 0.375523872071694 | 0.763710984076276 | 0.0247480712832487 |
| FP | 8.96217083831413e-12 | 0.48263483085027 | 5.59117560954067e-10 | 0.443600326538888 | 2.12613074655524e-08 | 0.40460205231194 |
| IFG | 0.00244352335385896 | 0.578637514306055 | 0.00139161185807216 | 0.603869284584617 | 0.0681053732892479 | 0.370715345719371 |
| PG | 1.0755315065259e-08 | 0.404002993708912 | 2.5743212021007e-10 | 0.442420558103563 | 0.157024334515327 | 0.104183620318616 |
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Relation with AD stages for CKLF-CMTM1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_551721 | chr16_66553085_+ | 5.74295548196361e-05 | 0.377119765761573 |
| CER | ADediting_551748 | chr16_66557194_+ | 0.000244806539874926 | 0.345979775267539 |
| CER | ADediting_551750 | chr16_66557207_+ | 0.000508010699965348 | 0.328991436801384 |
| CER | ADediting_551778 | chr16_66562270_+ | 0.0014488679099813 | 0.302748806446707 |
| CER | ADediting_551781 | chr16_66562801_+ | 8.88041513990515e-05 | 0.368088644977533 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 0.000148906886895095 | 0.357020714423897 |
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RelatedDrugs for CKLF-CMTM1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CKLF-CMTM1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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