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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for MSANTD3-TMEFF1 |
 Gene summary |
| Gene information | Gene symbol | MSANTD3-TMEFF1 | Gene ID | 100526694 |
| Gene name | MSANTD3-TMEFF1 readthrough | |
| Synonyms | C9orf2|C9orf3-TMEFF1|C9orf30-TMEFF1|H7365|TMEFF1|TR-1 | |
| Cytomap | 9q31.1 | |
| Type of gene | protein-coding | |
| Description | MSANTD3-TMEFF1 fusion proteinC9orf30-TMEFF1 readthroughTomoregulin-1Transmembrane protein with EGF-like and one follistatin-like domain | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for MSANTD3-TMEFF1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_1427894(100442624, +), ADediting_1427895(100442625, +), ADediting_1427896(100442652, +), ADediting_1427897(100442662, +), ADediting_1427898(100448094, +), ADediting_1427899(100452412, +), ADediting_1427900(100452437, +), ADediting_1427901(100452464, +), ADediting_1427902(100452477, +), ADediting_1427903(100452488, +), ADediting_1427904(100452501, +), ADediting_1427905(100452513, +), ADediting_1427906(100452523, +), ADediting_1427907(100452533, +), ADediting_1427908(100452575, +), ADediting_1427909(100452591, +), ADediting_1427910(100452604, +), ADediting_1427911(100452646, +), ADediting_1427912(100452657, +), ADediting_1427913(100452663, +), ADediting_1427914(100454624, +), ADediting_1427915(100454625, +), ADediting_1427916(100454630, +), ADediting_1427917(100454646, +), ADediting_1427918(100454670, +), ADediting_1427919(100454681, +), ADediting_1427920(100454693, +), ADediting_1427921(100454694, +), ADediting_1427922(100454729, +), ADediting_1427923(100454730, +), ADediting_1427924(100454738, +), ADediting_1427925(100454750, +), ADediting_1427926(100454760, +), ADediting_1427927(100454761, +), ADediting_1427928(100454770, +), ADediting_1427929(100454788, +), ADediting_1427930(100454801, +), ADediting_1427931(100454802, +), ADediting_1427932(100454806, +), ADediting_1427933(100454831, +), ADediting_1427934(100454846, +), ADediting_1427935(100454871, +), ADediting_1427936(100457321, +), ADediting_1427937(100457335, +), ADediting_1427938(100457336, +), ADediting_1427939(100458380, +), ADediting_1427940(100458388, +), ADediting_1427941(100458397, +), ADediting_1427942(100458401, +), ADediting_1427943(100458415, +), ADediting_1427944(100458459, +), ADediting_1427945(100458556, +), ADediting_1427946(100458574, +), ADediting_1427947(100462345, +), ADediting_1427948(100463584, +), ADediting_1427949(100465013, +), ADediting_1427950(100466677, +), ADediting_1427951(100483247, +), ADediting_1427952(100493928, +), ADediting_1427953(100493974, +), ADediting_1427954(100493982, +), ADediting_1427955(100493999, +), ADediting_1427956(100494029, +), ADediting_1427957(100494030, +), ADediting_1427958(100494031, +), ADediting_1427959(100494127, +), ADediting_1427960(100494132, +), ADediting_1427961(100494164, +), ADediting_1427962(100496340, +), ADediting_1427963(100501774, +), ADediting_1427964(100501802, +), ADediting_1427965(100501917, +), ADediting_1427966(100505256, +), ADediting_1427967(100505292, +), ADediting_1427968(100505301, +), ADediting_1427969(100506494, +), ADediting_1427970(100509519, +), ADediting_1427971(100509554, +), ADediting_1427972(100509562, +), ADediting_1427973(100509596, +), ADediting_1427974(100509653, +), ADediting_1427975(100509680, +), ADediting_1427976(100509731, +), ADediting_1427977(100510531, +), ADediting_1427978(100510537, +), ADediting_1427979(100510540, +), ADediting_1427980(100510544, +), ADediting_1427981(100510549, +), ADediting_1427982(100510563, +), ADediting_1427983(100510582, +), ADediting_1427984(100510599, +), ADediting_1427985(100510664, +), ADediting_1427986(100510675, +), ADediting_1427987(100510684, +), ADediting_1427988(100510689, +), ADediting_1427989(100510714, +), ADediting_1427990(100510736, +), ADediting_1427991(100510737, +), ADediting_1427992(100510749, +), ADediting_1427993(100526885, +), ADediting_1427994(100526900, +), ADediting_1427995(100526914, +), ADediting_1427996(100527023, +), ADediting_1427997(100535650, +), ADediting_1427998(100539141, +), ADediting_1427999(100572212, +), ADediting_1591794(100454684, +), ADediting_1591795(100454838, +), ADediting_1591796(100510649, +), ADediting_1671283(100477725, +), ADediting_1671284(100509695, +), ADediting_1671285(100509699, +), ADediting_1671286(100572220, +), |
Top |
RNA editing positional annotations for MSANTD3-TMEFF1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1427894 | chr9_100442624_+ | intronic |
| ADediting_1427895 | chr9_100442625_+ | intronic |
| ADediting_1427896 | chr9_100442652_+ | intronic |
| ADediting_1427897 | chr9_100442662_+ | intronic |
| ADediting_1427898 | chr9_100448094_+ | intronic |
| ADediting_1427899 | chr9_100452412_+ | intronic |
| ADediting_1427900 | chr9_100452437_+ | intronic |
| ADediting_1427901 | chr9_100452464_+ | intronic |
| ADediting_1427902 | chr9_100452477_+ | intronic |
| ADediting_1427903 | chr9_100452488_+ | intronic |
| ADediting_1427904 | chr9_100452501_+ | intronic |
| ADediting_1427905 | chr9_100452513_+ | intronic |
| ADediting_1427906 | chr9_100452523_+ | intronic |
| ADediting_1427907 | chr9_100452533_+ | intronic |
| ADediting_1427908 | chr9_100452575_+ | intronic |
| ADediting_1427909 | chr9_100452591_+ | intronic |
| ADediting_1427910 | chr9_100452604_+ | intronic |
| ADediting_1427911 | chr9_100452646_+ | intronic |
| ADediting_1427912 | chr9_100452657_+ | intronic |
| ADediting_1427913 | chr9_100452663_+ | intronic |
| ADediting_1427914 | chr9_100454624_+ | intronic |
| ADediting_1427915 | chr9_100454625_+ | intronic |
| ADediting_1427916 | chr9_100454630_+ | intronic |
| ADediting_1427917 | chr9_100454646_+ | intronic |
| ADediting_1427918 | chr9_100454670_+ | intronic |
| ADediting_1427919 | chr9_100454681_+ | intronic |
| ADediting_1427920 | chr9_100454693_+ | intronic |
| ADediting_1427921 | chr9_100454694_+ | intronic |
| ADediting_1427922 | chr9_100454729_+ | intronic |
| ADediting_1427923 | chr9_100454730_+ | intronic |
| ADediting_1427924 | chr9_100454738_+ | intronic |
| ADediting_1427925 | chr9_100454750_+ | intronic |
| ADediting_1427926 | chr9_100454760_+ | intronic |
| ADediting_1427927 | chr9_100454761_+ | intronic |
| ADediting_1427928 | chr9_100454770_+ | intronic |
| ADediting_1427929 | chr9_100454788_+ | intronic |
| ADediting_1427930 | chr9_100454801_+ | intronic |
| ADediting_1427931 | chr9_100454802_+ | intronic |
| ADediting_1427932 | chr9_100454806_+ | intronic |
| ADediting_1427933 | chr9_100454831_+ | intronic |
| ADediting_1427934 | chr9_100454846_+ | intronic |
| ADediting_1427935 | chr9_100454871_+ | intronic |
| ADediting_1427936 | chr9_100457321_+ | intronic |
| ADediting_1427937 | chr9_100457335_+ | intronic |
| ADediting_1427938 | chr9_100457336_+ | intronic |
| ADediting_1427939 | chr9_100458380_+ | intronic |
| ADediting_1427940 | chr9_100458388_+ | intronic |
| ADediting_1427941 | chr9_100458397_+ | intronic |
| ADediting_1427942 | chr9_100458401_+ | intronic |
| ADediting_1427943 | chr9_100458415_+ | intronic |
| ADediting_1427944 | chr9_100458459_+ | intronic |
| ADediting_1427945 | chr9_100458556_+ | intronic |
| ADediting_1427946 | chr9_100458574_+ | intronic |
| ADediting_1427947 | chr9_100462345_+ | intronic |
| ADediting_1427948 | chr9_100463584_+ | intronic |
| ADediting_1427949 | chr9_100465013_+ | intronic |
| ADediting_1427950 | chr9_100466677_+ | intronic |
| ADediting_1427951 | chr9_100483247_+ | intronic |
| ADediting_1427952 | chr9_100493928_+ | intronic |
| ADediting_1427953 | chr9_100493974_+ | intronic |
| ADediting_1427954 | chr9_100493982_+ | intronic |
| ADediting_1427955 | chr9_100493999_+ | intronic |
| ADediting_1427956 | chr9_100494029_+ | intronic |
| ADediting_1427957 | chr9_100494030_+ | intronic |
| ADediting_1427958 | chr9_100494031_+ | intronic |
| ADediting_1427959 | chr9_100494127_+ | intronic |
| ADediting_1427960 | chr9_100494132_+ | intronic |
| ADediting_1427961 | chr9_100494164_+ | intronic |
| ADediting_1427962 | chr9_100496340_+ | intronic |
| ADediting_1427963 | chr9_100501774_+ | intronic |
| ADediting_1427964 | chr9_100501802_+ | intronic |
| ADediting_1427965 | chr9_100501917_+ | intronic |
| ADediting_1427966 | chr9_100505256_+ | intronic |
| ADediting_1427967 | chr9_100505292_+ | intronic |
| ADediting_1427968 | chr9_100505301_+ | intronic |
| ADediting_1427969 | chr9_100506494_+ | intronic |
| ADediting_1427970 | chr9_100509519_+ | intronic |
| ADediting_1427971 | chr9_100509554_+ | intronic |
| ADediting_1427972 | chr9_100509562_+ | intronic |
| ADediting_1427973 | chr9_100509596_+ | intronic |
| ADediting_1427974 | chr9_100509653_+ | intronic |
| ADediting_1427975 | chr9_100509680_+ | intronic |
| ADediting_1427976 | chr9_100509731_+ | intronic |
| ADediting_1427977 | chr9_100510531_+ | intronic |
| ADediting_1427978 | chr9_100510537_+ | intronic |
| ADediting_1427979 | chr9_100510540_+ | intronic |
| ADediting_1427980 | chr9_100510544_+ | intronic |
| ADediting_1427981 | chr9_100510549_+ | intronic |
| ADediting_1427982 | chr9_100510563_+ | intronic |
| ADediting_1427983 | chr9_100510582_+ | intronic |
| ADediting_1427984 | chr9_100510599_+ | intronic |
| ADediting_1427985 | chr9_100510664_+ | intronic |
| ADediting_1427986 | chr9_100510675_+ | intronic |
| ADediting_1427987 | chr9_100510684_+ | intronic |
| ADediting_1427988 | chr9_100510689_+ | intronic |
| ADediting_1427989 | chr9_100510714_+ | intronic |
| ADediting_1427990 | chr9_100510736_+ | intronic |
| ADediting_1427991 | chr9_100510737_+ | intronic |
| ADediting_1427992 | chr9_100510749_+ | intronic |
| ADediting_1427993 | chr9_100526885_+ | intronic |
| ADediting_1427994 | chr9_100526900_+ | intronic |
| ADediting_1427995 | chr9_100526914_+ | intronic |
| ADediting_1427996 | chr9_100527023_+ | intronic |
| ADediting_1427997 | chr9_100535650_+ | intronic |
| ADediting_1427998 | chr9_100539141_+ | intronic |
| ADediting_1427999 | chr9_100572212_+ | intronic |
| ADediting_1591794 | chr9_100454684_+ | intronic |
| ADediting_1591795 | chr9_100454838_+ | intronic |
| ADediting_1591796 | chr9_100510649_+ | intronic |
| ADediting_1671283 | chr9_100477725_+ | intronic |
| ADediting_1671284 | chr9_100509695_+ | intronic |
| ADediting_1671285 | chr9_100509699_+ | intronic |
| ADediting_1671286 | chr9_100572220_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1427894 | chr9_100442624_+ | SINE | Alu | Name=AluJo |
| ADediting_1427895 | chr9_100442625_+ | SINE | Alu | Name=AluJo |
| ADediting_1427896 | chr9_100442652_+ | SINE | Alu | Name=AluJo |
| ADediting_1427897 | chr9_100442662_+ | SINE | Alu | Name=AluJo |
| ADediting_1427898 | chr9_100448094_+ | SINE | Alu | Name=AluSz |
| ADediting_1427899 | chr9_100452412_+ | SINE | Alu | Name=AluY |
| ADediting_1427900 | chr9_100452437_+ | SINE | Alu | Name=AluY |
| ADediting_1427901 | chr9_100452464_+ | SINE | Alu | Name=AluY |
| ADediting_1427902 | chr9_100452477_+ | SINE | Alu | Name=AluY |
| ADediting_1427903 | chr9_100452488_+ | SINE | Alu | Name=AluY |
| ADediting_1427904 | chr9_100452501_+ | SINE | Alu | Name=AluY |
| ADediting_1427905 | chr9_100452513_+ | SINE | Alu | Name=AluY |
| ADediting_1427906 | chr9_100452523_+ | SINE | Alu | Name=AluY |
| ADediting_1427907 | chr9_100452533_+ | SINE | Alu | Name=AluY |
| ADediting_1427908 | chr9_100452575_+ | SINE | Alu | Name=AluY |
| ADediting_1427909 | chr9_100452591_+ | SINE | Alu | Name=AluY |
| ADediting_1427910 | chr9_100452604_+ | SINE | Alu | Name=AluY |
| ADediting_1427911 | chr9_100452646_+ | SINE | Alu | Name=AluY |
| ADediting_1427912 | chr9_100452657_+ | SINE | Alu | Name=AluY |
| ADediting_1427913 | chr9_100452663_+ | SINE | Alu | Name=AluY |
| ADediting_1427914 | chr9_100454624_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427915 | chr9_100454625_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427916 | chr9_100454630_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427917 | chr9_100454646_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427918 | chr9_100454670_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427919 | chr9_100454681_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427920 | chr9_100454693_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427921 | chr9_100454694_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427922 | chr9_100454729_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427923 | chr9_100454730_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427924 | chr9_100454738_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427925 | chr9_100454750_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427926 | chr9_100454760_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427927 | chr9_100454761_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427928 | chr9_100454770_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427929 | chr9_100454788_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427930 | chr9_100454801_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427931 | chr9_100454802_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427932 | chr9_100454806_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427933 | chr9_100454831_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427934 | chr9_100454846_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427935 | chr9_100454871_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427936 | chr9_100457321_+ | SINE | Alu | Name=AluSg |
| ADediting_1427937 | chr9_100457335_+ | SINE | Alu | Name=AluSg |
| ADediting_1427938 | chr9_100457336_+ | SINE | Alu | Name=AluSg |
| ADediting_1427939 | chr9_100458380_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1427940 | chr9_100458388_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1427941 | chr9_100458397_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1427942 | chr9_100458401_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1427943 | chr9_100458415_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1427944 | chr9_100458459_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1427945 | chr9_100458556_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1427946 | chr9_100458574_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1427947 | chr9_100462345_+ | SINE | Alu | Name=AluSz |
| ADediting_1427948 | chr9_100463584_+ | SINE | Alu | Name=AluSq |
| ADediting_1427949 | chr9_100465013_+ | SINE | Alu | Name=AluSc8 |
| ADediting_1427950 | chr9_100466677_+ | SINE | Alu | Name=AluJr4 |
| ADediting_1427951 | chr9_100483247_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1427952 | chr9_100493928_+ | SINE | Alu | Name=AluJb |
| ADediting_1427953 | chr9_100493974_+ | SINE | Alu | Name=AluJb |
| ADediting_1427954 | chr9_100493982_+ | SINE | Alu | Name=AluJb |
| ADediting_1427955 | chr9_100493999_+ | SINE | Alu | Name=AluJb |
| ADediting_1427956 | chr9_100494029_+ | SINE | Alu | Name=AluJb |
| ADediting_1427957 | chr9_100494030_+ | SINE | Alu | Name=AluJb |
| ADediting_1427958 | chr9_100494031_+ | SINE | Alu | Name=AluJb |
| ADediting_1427959 | chr9_100494127_+ | SINE | Alu | Name=AluJb |
| ADediting_1427960 | chr9_100494132_+ | SINE | Alu | Name=AluJb |
| ADediting_1427961 | chr9_100494164_+ | SINE | Alu | Name=AluJb |
| ADediting_1427962 | chr9_100496340_+ | SINE | Alu | Name=AluSx |
| ADediting_1427963 | chr9_100501774_+ | SINE | Alu | Name=AluSc |
| ADediting_1427964 | chr9_100501802_+ | SINE | Alu | Name=AluSc |
| ADediting_1427965 | chr9_100501917_+ | SINE | Alu | Name=AluSc |
| ADediting_1427966 | chr9_100505256_+ | SINE | Alu | Name=AluSc5 |
| ADediting_1427967 | chr9_100505292_+ | SINE | Alu | Name=AluSc5 |
| ADediting_1427968 | chr9_100505301_+ | SINE | Alu | Name=AluSc5 |
| ADediting_1427969 | chr9_100506494_+ | SINE | Alu | Name=AluY |
| ADediting_1427970 | chr9_100509519_+ | SINE | Alu | Name=AluY |
| ADediting_1427971 | chr9_100509554_+ | SINE | Alu | Name=AluY |
| ADediting_1427972 | chr9_100509562_+ | SINE | Alu | Name=AluY |
| ADediting_1427973 | chr9_100509596_+ | SINE | Alu | Name=AluY |
| ADediting_1427974 | chr9_100509653_+ | SINE | Alu | Name=AluY |
| ADediting_1427975 | chr9_100509680_+ | SINE | Alu | Name=AluY |
| ADediting_1427976 | chr9_100509731_+ | SINE | Alu | Name=AluY |
| ADediting_1427977 | chr9_100510531_+ | SINE | Alu | Name=AluJb |
| ADediting_1427978 | chr9_100510537_+ | SINE | Alu | Name=AluJb |
| ADediting_1427979 | chr9_100510540_+ | SINE | Alu | Name=AluJb |
| ADediting_1427980 | chr9_100510544_+ | SINE | Alu | Name=AluJb |
| ADediting_1427981 | chr9_100510549_+ | SINE | Alu | Name=AluJb |
| ADediting_1427982 | chr9_100510563_+ | SINE | Alu | Name=AluJb |
| ADediting_1427983 | chr9_100510582_+ | SINE | Alu | Name=AluJb |
| ADediting_1427984 | chr9_100510599_+ | SINE | Alu | Name=AluJb |
| ADediting_1427985 | chr9_100510664_+ | SINE | Alu | Name=AluJb |
| ADediting_1427986 | chr9_100510675_+ | SINE | Alu | Name=AluJb |
| ADediting_1427987 | chr9_100510684_+ | SINE | Alu | Name=AluJb |
| ADediting_1427988 | chr9_100510689_+ | SINE | Alu | Name=AluJb |
| ADediting_1427989 | chr9_100510714_+ | SINE | Alu | Name=AluJb |
| ADediting_1427990 | chr9_100510736_+ | SINE | Alu | Name=AluJb |
| ADediting_1427991 | chr9_100510737_+ | SINE | Alu | Name=AluJb |
| ADediting_1427992 | chr9_100510749_+ | SINE | Alu | Name=AluJb |
| ADediting_1427993 | chr9_100526885_+ | SINE | Alu | Name=AluSx |
| ADediting_1427994 | chr9_100526900_+ | SINE | Alu | Name=AluSx |
| ADediting_1427995 | chr9_100526914_+ | SINE | Alu | Name=AluSx |
| ADediting_1427996 | chr9_100527023_+ | SINE | Alu | Name=AluSx |
| ADediting_1427997 | chr9_100535650_+ | SINE | Alu | Name=AluSz6 |
| ADediting_1427998 | chr9_100539141_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1427999 | chr9_100572212_+ | LINE | L1 | Name=L1M4 |
| ADediting_1591794 | chr9_100454684_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1591795 | chr9_100454838_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1591796 | chr9_100510649_+ | SINE | Alu | Name=AluJb |
| ADediting_1671283 | chr9_100477725_+ | SINE | Alu | Name=AluSx |
| ADediting_1671284 | chr9_100509695_+ | SINE | Alu | Name=AluY |
| ADediting_1671285 | chr9_100509699_+ | SINE | Alu | Name=AluY |
| ADediting_1671286 | chr9_100572220_+ | LINE | L1 | Name=L1M4 |
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RNA A-to-I editing events in the alternative splicing sites for MSANTD3-TMEFF1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MSANTD3-TMEFF1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for MSANTD3-TMEFF1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for MSANTD3-TMEFF1 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_843620 | chr2_207754818_+ | ENSG00000251349.3 | ENST00000502978.1 | MSANTD3-TMEFF1-201 | hsa-miR-4775 | chr9 | 100577574 | 100577580 | 7mer-m8 | 100577560 | 100577581 | 146 | -5.01 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000251349.3 | ENST00000502978.1 | MSANTD3-TMEFF1-201 | hsa-miR-5585-3p | chr9 | 100577535 | 100577541 | 7mer-1a | 100577521 | 100577541 | 141 | -15.04 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000251349.3 | ENST00000502978.1 | MSANTD3-TMEFF1-201 | hsa-miR-5585-3p | chr9 | 100577535 | 100577541 | 7mer-1a | 100577521 | 100577541 | 141 | -15.04 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for MSANTD3-TMEFF1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for MSANTD3-TMEFF1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| TCX | ADediting_1427899 | chr9_100452412_+ | 6.23012097413572e-05 | 0.320913715120208 | 2.96440088484969e-05 | 0.333936784084189 | 0.29915365283916 | -0.0853318708215732 |
| DLPFC | ADediting_1427902 | chr9_100452477_+ | 1.0325201608947e-07 | 0.296578912734379 | 1.45524404569589e-08 | 0.314897553885443 | 0.000882490713523191 | 0.187950935918509 |
| DLPFC | ADediting_1427906 | chr9_100452523_+ | 4.55597754956184e-07 | 0.281798791672335 | 0.00037329084445803 | 0.200844957228916 | 1.67454279829414e-08 | 0.313626105209558 |
| DLPFC | ADediting_1427909 | chr9_100452591_+ | 1.3409334952658e-06 | 0.270487763764632 | 0.00416545813427107 | 0.162316217533629 | 1.34562916423882e-12 | 0.388316297626882 |
| DLPFC | ADediting_1427910 | chr9_100452604_+ | 3.93891224279699e-06 | 0.2586616472359 | 0.00116234251352824 | 0.18364247788513 | 4.78559076699191e-09 | 0.324766711649841 |
| DLPFC | ADediting_1427911 | chr9_100452646_+ | 1.1788780672745e-09 | 0.336715856023507 | 4.58876940286278e-11 | 0.362592402093076 | 0.000112215058643476 | 0.217621648300963 |
| CER | ADediting_1427911 | chr9_100452646_+ | 5.01598314834518e-05 | 0.324776055516491 | 5.30976523323115e-05 | 0.32376693422737 | 0.703062348423209 | 0.0313788562465632 |
| TCX | ADediting_1427911 | chr9_100452646_+ | 0.00121382428914666 | 0.261754563616666 | 0.000137449384379953 | 0.30635056580656 | 0.579567157383015 | -0.0455931791403936 |
| DLPFC | ADediting_1427912 | chr9_100452657_+ | 4.72149423159651e-08 | 0.304045863686228 | 2.03315202494038e-10 | 0.351017996233144 | 8.15383559417823e-05 | 0.221868625649586 |
| CER | ADediting_1427912 | chr9_100452657_+ | 1.07558499492993e-07 | 0.417368429254384 | 2.16409095843659e-07 | 0.408156481323266 | 0.88052550123839 | 0.0123752502853979 |
| TCX | ADediting_1427912 | chr9_100452657_+ | 8.50304537109495e-05 | 0.315278604822943 | 7.68524725092859e-05 | 0.317123005304674 | 0.668759289662438 | 0.0352176946069863 |
| DLPFC | ADediting_1427913 | chr9_100452663_+ | 8.18128821750132e-07 | 0.27572788322986 | 7.39799731915545e-09 | 0.320943612448086 | 0.00161948074608503 | 0.178326051023668 |
| CER | ADediting_1427913 | chr9_100452663_+ | 3.93522973466175e-05 | 0.329038824293821 | 1.50244373905908e-06 | 0.38107213667837 | 0.995077644859 | 0.000507970336448485 |
| TCX | ADediting_1427913 | chr9_100452663_+ | 0.00426846035170387 | 0.232070067274755 | 5.75509886932164e-05 | 0.322332922178618 | 0.786289189827637 | -0.022321842926005 |
| CER | ADediting_1427914 | chr9_100454624_+ | 6.38395798021694e-06 | 0.359139931012244 | 3.26745457478532e-05 | 0.332263267254888 | 0.798444149574803 | -0.0210237215831879 |
| DLPFC | ADediting_1427915 | chr9_100454625_+ | 5.0241557794734e-15 | 0.424972400733644 | 2.05638660613497e-14 | 0.416146056421579 | 0.00152711213957785 | 0.179278052447361 |
| CER | ADediting_1427915 | chr9_100454625_+ | 3.66925724112048e-07 | 0.401011587373776 | 3.02890983681164e-06 | 0.370643528542872 | 0.808911365161103 | 0.0199099912174016 |
| CER | ADediting_1427917 | chr9_100454646_+ | 4.31806941617557e-05 | 0.327415405839947 | 2.11391595352011e-07 | 0.408470092550041 | 0.502844448744996 | 0.055126517483869 |
| CER | ADediting_1427918 | chr9_100454670_+ | 0.00775719737851461 | 0.216613651088359 | 4.05757935588598e-05 | 0.328504451854381 | 0.381783501465713 | -0.0719211208478683 |
| CER | ADediting_1427925 | chr9_100454750_+ | 9.49139412255097e-06 | 0.352834446805203 | 1.3972900056776e-06 | 0.382131071865628 | 0.867593534979318 | -0.0137264897303473 |
| DLPFC | ADediting_1427926 | chr9_100454760_+ | 1.61354755492703e-08 | 0.313962785820081 | 3.49257720353584e-08 | 0.306867738019357 | 0.000483052944474033 | 0.197066517504565 |
| CER | ADediting_1427926 | chr9_100454760_+ | 1.2271952114262e-05 | 0.348676424710244 | 9.55395171864891e-06 | 0.352728859963125 | 0.707552894921031 | 0.0308814619756901 |
| DLPFC | ADediting_1427927 | chr9_100454761_+ | 4.11925442140564e-10 | 0.345359042993962 | 3.04736730145342e-10 | 0.347788413001469 | 0.000343067291543523 | 0.202067776038646 |
| CER | ADediting_1427927 | chr9_100454761_+ | 5.69986739785413e-06 | 0.36091762298355 | 4.77763718396798e-05 | 0.325636363662004 | 0.952518846333505 | -0.00490272915860603 |
| CER | ADediting_1427928 | chr9_100454770_+ | 7.86279619030182e-08 | 0.421408823803387 | 2.50620143270264e-07 | 0.406187043189268 | 0.275065826426203 | 0.0896887569858293 |
| DLPFC | ADediting_1427929 | chr9_100454788_+ | 1.44016352100111e-15 | 0.432587888209742 | 1.5343093081038e-15 | 0.432206517730655 | 2.5088301680926e-05 | 0.236881196963128 |
| CER | ADediting_1427929 | chr9_100454788_+ | 3.59033891650612e-06 | 0.368058686687199 | 6.883838716384e-06 | 0.357951629909935 | 0.809795700791477 | -0.0198160641878625 |
| DLPFC | ADediting_1427932 | chr9_100454806_+ | 2.29810374536409e-11 | 0.367814914056461 | 3.92654698621452e-09 | 0.326485733963781 | 0.000368052081494818 | 0.201050151827361 |
| CER | ADediting_1427932 | chr9_100454806_+ | 4.8544792101069e-07 | 0.397154930725996 | 1.11395215152093e-06 | 0.385414750424022 | 0.717243849315066 | 0.0298118121129645 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 2.54423437430118e-30 | 0.588866169678017 | 1.79388790562984e-27 | 0.564382759458389 | 0.280955179841395 | -0.0614265918702131 |
| AC | 4.51003634522761e-69 | 0.844078518686801 | 2.4152948464547e-72 | 0.854042797226002 | 2.18794133519127e-08 | 0.344766476299298 |
| PCC | 3.5531913633103e-30 | 0.706363876589255 | 1.60563683042793e-35 | 0.748245154355137 | 0.0869047101345872 | 0.124208009425463 |
| CER | 4.11134745720326e-17 | 0.61713079453912 | 2.35667386268288e-17 | 0.620838963229754 | 0.0181768024033621 | 0.192657555585971 |
| TCX | 5.06132938234837e-19 | 0.645159791805709 | 2.29398897652254e-11 | 0.511301348249716 | 0.414207031608897 | 0.0671544483725961 |
| FP | 3.41844617375851e-05 | 0.30528237237886 | 3.27963517677766e-10 | 0.448924185880647 | 0.198550696813339 | -0.0968222274249961 |
| IFG | 0.0394406757892445 | 0.414398780529491 | 0.124238132031286 | 0.315683852569425 | 0.354699563776825 | -0.193242683762495 |
| PG | 9.58020403120218e-43 | 0.800353370261786 | 3.69712470155899e-21 | 0.620252397319371 | 0.719809716914966 | -0.026475992484922 |
| STG | 7.54608855902071e-08 | 0.546500179375347 | 1.15977142538378e-09 | 0.604248707661238 | 0.273365751927232 | -0.120884289438014 |
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Relation with AD stages for MSANTD3-TMEFF1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| IFG | 0.0203694277534146 | -0.461022193222986 |
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RelatedDrugs for MSANTD3-TMEFF1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MSANTD3-TMEFF1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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