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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for LINC00674

check button Gene summary
Gene informationGene symbol

LINC00674

Gene ID

100499466

Gene namelong intergenic non-protein coding RNA 674
Synonyms-
Cytomap

17q24.2

Type of genencRNA
Description-
Modification date20200313
UniProtAcc

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for LINC00674

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_659033(68105270, +), ADediting_659034(68108707, +), ADediting_659035(68108740, +), ADediting_659036(68108753, +), ADediting_659037(68108754, +), ADediting_659038(68108880, +), ADediting_659039(68109064, +), ADediting_659040(68109098, +), ADediting_659041(68109126, +), ADediting_659042(68109151, +), ADediting_659043(68109167, +), ADediting_659044(68109183, +), ADediting_659045(68109187, +), ADediting_659046(68109196, +), ADediting_659047(68110406, +), ADediting_659048(68110409, +), ADediting_659049(68110429, +), ADediting_659050(68111194, +), ADediting_659051(68111202, +), ADediting_659052(68111923, +), ADediting_659053(68112093, +), ADediting_659054(68112387, +), ADediting_659055(68112438, +), ADediting_659056(68112443, +), ADediting_659057(68112447, +), ADediting_659058(68112462, +), ADediting_659059(68112465, +), ADediting_659060(68112485, +), ADediting_659061(68112486, +), ADediting_659062(68112551, +), ADediting_659063(68112579, +), ADediting_659064(68112584, +), ADediting_659065(68112597, +), ADediting_659066(68112613, +), ADediting_659067(68112622, +), ADediting_659068(68112657, +), ADediting_659069(68114156, +), ADediting_659070(68115079, +), ADediting_659071(68115091, +), ADediting_659072(68115100, +), ADediting_659073(68115116, +), ADediting_659074(68115135, +), ADediting_659075(68115136, +), ADediting_659076(68115138, +), ADediting_659077(68115148, +), ADediting_659078(68115153, +), ADediting_659079(68115162, +), ADediting_659080(68115165, +), ADediting_659081(68115175, +), ADediting_659082(68115177, +), ADediting_659083(68115181, +), ADediting_659084(68115183, +), ADediting_659085(68115184, +), ADediting_659086(68115188, +), ADediting_659087(68115201, +), ADediting_659088(68115210, +), ADediting_659089(68115221, +), ADediting_659090(68115238, +), ADediting_659091(68115247, +), ADediting_659092(68115259, +), ADediting_659093(68115260, +), ADediting_659094(68115272, +), ADediting_659095(68115273, +), ADediting_659096(68115276, +), ADediting_659097(68115300, +), ADediting_659098(68115312, +), ADediting_1548400(68115202, +), ADediting_1548401(68115211, +), ADediting_1628590(68111990, +),

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RNA editing positional annotations for LINC00674 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_659033chr17_68105270_+ncRNA_intronic
ADediting_659034chr17_68108707_+ncRNA_intronic
ADediting_659035chr17_68108740_+ncRNA_intronic
ADediting_659036chr17_68108753_+ncRNA_intronic
ADediting_659037chr17_68108754_+ncRNA_intronic
ADediting_659038chr17_68108880_+ncRNA_intronic
ADediting_659039chr17_68109064_+ncRNA_intronic
ADediting_659040chr17_68109098_+ncRNA_intronic
ADediting_659041chr17_68109126_+ncRNA_intronic
ADediting_659042chr17_68109151_+ncRNA_intronic
ADediting_659043chr17_68109167_+ncRNA_intronic
ADediting_659044chr17_68109183_+ncRNA_intronic
ADediting_659045chr17_68109187_+ncRNA_intronic
ADediting_659046chr17_68109196_+ncRNA_intronic
ADediting_659047chr17_68110406_+ncRNA_intronic
ADediting_659048chr17_68110409_+ncRNA_intronic
ADediting_659049chr17_68110429_+ncRNA_intronic
ADediting_659050chr17_68111194_+ncRNA_intronic
ADediting_659051chr17_68111202_+ncRNA_intronic
ADediting_659052chr17_68111923_+ncRNA_intronic
ADediting_659053chr17_68112093_+ncRNA_intronic
ADediting_659054chr17_68112387_+ncRNA_intronic
ADediting_659055chr17_68112438_+ncRNA_intronic
ADediting_659056chr17_68112443_+ncRNA_intronic
ADediting_659057chr17_68112447_+ncRNA_intronic
ADediting_659058chr17_68112462_+ncRNA_intronic
ADediting_659059chr17_68112465_+ncRNA_intronic
ADediting_659060chr17_68112485_+ncRNA_intronic
ADediting_659061chr17_68112486_+ncRNA_intronic
ADediting_659062chr17_68112551_+ncRNA_intronic
ADediting_659063chr17_68112579_+ncRNA_intronic
ADediting_659064chr17_68112584_+ncRNA_intronic
ADediting_659065chr17_68112597_+ncRNA_intronic
ADediting_659066chr17_68112613_+ncRNA_intronic
ADediting_659067chr17_68112622_+ncRNA_intronic
ADediting_659068chr17_68112657_+ncRNA_intronic
ADediting_659069chr17_68114156_+ncRNA_intronic
ADediting_659070chr17_68115079_+ncRNA_exonic
ADediting_659071chr17_68115091_+ncRNA_exonic
ADediting_659072chr17_68115100_+ncRNA_exonic
ADediting_659073chr17_68115116_+ncRNA_exonic
ADediting_659074chr17_68115135_+ncRNA_exonic
ADediting_659075chr17_68115136_+ncRNA_exonic
ADediting_659076chr17_68115138_+ncRNA_exonic
ADediting_659077chr17_68115148_+ncRNA_exonic
ADediting_659078chr17_68115153_+ncRNA_exonic
ADediting_659079chr17_68115162_+ncRNA_exonic
ADediting_659080chr17_68115165_+ncRNA_exonic
ADediting_659081chr17_68115175_+ncRNA_exonic
ADediting_659082chr17_68115177_+ncRNA_exonic
ADediting_659083chr17_68115181_+ncRNA_exonic
ADediting_659084chr17_68115183_+ncRNA_exonic
ADediting_659085chr17_68115184_+ncRNA_exonic
ADediting_659086chr17_68115188_+ncRNA_exonic
ADediting_659087chr17_68115201_+ncRNA_exonic
ADediting_659088chr17_68115210_+ncRNA_exonic
ADediting_659089chr17_68115221_+ncRNA_exonic
ADediting_659090chr17_68115238_+ncRNA_exonic
ADediting_659091chr17_68115247_+ncRNA_exonic
ADediting_659092chr17_68115259_+ncRNA_exonic
ADediting_659093chr17_68115260_+ncRNA_exonic
ADediting_659094chr17_68115272_+ncRNA_exonic
ADediting_659095chr17_68115273_+ncRNA_exonic
ADediting_659096chr17_68115276_+ncRNA_exonic
ADediting_659097chr17_68115300_+ncRNA_exonic
ADediting_659098chr17_68115312_+ncRNA_exonic
ADediting_1548400chr17_68115202_+ncRNA_exonic
ADediting_1548401chr17_68115211_+ncRNA_exonic
ADediting_1628590chr17_68111990_+ncRNA_intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_659033chr17_68105270_+SINEAluName=AluY
ADediting_659034chr17_68108707_+SINEAluName=AluSz
ADediting_659035chr17_68108740_+SINEAluName=AluSz
ADediting_659036chr17_68108753_+SINEAluName=AluSz
ADediting_659037chr17_68108754_+SINEAluName=AluSz
ADediting_659038chr17_68108880_+SINEAluName=AluSz
ADediting_659039chr17_68109064_+SINEAluName=AluSx
ADediting_659040chr17_68109098_+SINEAluName=AluSx
ADediting_659041chr17_68109126_+SINEAluName=AluSx
ADediting_659042chr17_68109151_+SINEAluName=AluSx
ADediting_659043chr17_68109167_+SINEAluName=AluSx
ADediting_659044chr17_68109183_+SINEAluName=AluSx
ADediting_659045chr17_68109187_+SINEAluName=AluSx
ADediting_659046chr17_68109196_+SINEAluName=AluSx
ADediting_659047chr17_68110406_+SINEAluName=AluSp
ADediting_659048chr17_68110409_+SINEAluName=AluSp
ADediting_659049chr17_68110429_+SINEAluName=AluSp
ADediting_659050chr17_68111194_+SINEAluName=AluJb
ADediting_659051chr17_68111202_+SINEAluName=AluJb
ADediting_659052chr17_68111923_+SINEAluName=AluSq2
ADediting_659053chr17_68112093_+SINEAluName=AluSq2
ADediting_659054chr17_68112387_+LINEL1Name=L1ME1
ADediting_659055chr17_68112438_+SINEAluName=AluSx1
ADediting_659056chr17_68112443_+SINEAluName=AluSx1
ADediting_659057chr17_68112447_+SINEAluName=AluSx1
ADediting_659058chr17_68112462_+SINEAluName=AluSx1
ADediting_659059chr17_68112465_+SINEAluName=AluSx1
ADediting_659060chr17_68112485_+SINEAluName=AluSx1
ADediting_659061chr17_68112486_+SINEAluName=AluSx1
ADediting_659062chr17_68112551_+SINEAluName=AluSx1
ADediting_659063chr17_68112579_+SINEAluName=AluSx1
ADediting_659064chr17_68112584_+SINEAluName=AluSx1
ADediting_659065chr17_68112597_+SINEAluName=AluSx1
ADediting_659066chr17_68112613_+SINEAluName=AluSx1
ADediting_659067chr17_68112622_+SINEAluName=AluSx1
ADediting_659068chr17_68112657_+SINEAluName=AluSx1
ADediting_659069chr17_68114156_+SINEAluName=AluJr4
ADediting_659070chr17_68115079_+SINEAluName=AluJb
ADediting_659071chr17_68115091_+SINEAluName=AluJb
ADediting_659072chr17_68115100_+SINEAluName=AluJb
ADediting_659073chr17_68115116_+SINEAluName=AluJb
ADediting_659074chr17_68115135_+SINEAluName=AluJb
ADediting_659075chr17_68115136_+SINEAluName=AluJb
ADediting_659076chr17_68115138_+SINEAluName=AluJb
ADediting_659077chr17_68115148_+SINEAluName=AluJb
ADediting_659078chr17_68115153_+SINEAluName=AluJb
ADediting_659079chr17_68115162_+SINEAluName=AluJb
ADediting_659080chr17_68115165_+SINEAluName=AluJb
ADediting_659081chr17_68115175_+SINEAluName=AluJb
ADediting_659082chr17_68115177_+SINEAluName=AluJb
ADediting_659083chr17_68115181_+SINEAluName=AluJb
ADediting_659084chr17_68115183_+SINEAluName=AluJb
ADediting_659085chr17_68115184_+SINEAluName=AluJb
ADediting_659086chr17_68115188_+SINEAluName=AluJb
ADediting_659087chr17_68115201_+SINEAluName=AluJb
ADediting_659088chr17_68115210_+SINEAluName=AluJb
ADediting_659089chr17_68115221_+SINEAluName=AluJb
ADediting_659090chr17_68115238_+SINEAluName=AluJb
ADediting_659091chr17_68115247_+SINEAluName=AluJb
ADediting_659092chr17_68115259_+SINEAluName=AluJb
ADediting_659093chr17_68115260_+SINEAluName=AluJb
ADediting_659094chr17_68115272_+SINEAluName=AluJb
ADediting_659095chr17_68115273_+SINEAluName=AluJb
ADediting_659096chr17_68115276_+SINEAluName=AluJb
ADediting_659097chr17_68115300_+SINEAluName=AluJb
ADediting_659098chr17_68115312_+SINEAluName=AluJb
ADediting_1548400chr17_68115202_+SINEAluName=AluJb
ADediting_1548401chr17_68115211_+SINEAluName=AluJb
ADediting_1628590chr17_68111990_+SINEAluName=AluSq2

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RNA A-to-I editing events in the alternative splicing sites for LINC00674

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LINC00674

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
Soverview
Soverview
Soverview

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
Soverview
Soverview
ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for LINC00674

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for LINC00674

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1548400chr17_68115202_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-4661-5pchr1768115197681152037mer-m86811518168115204158-21.7
ADediting_1548400chr17_68115202_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548ae-3pchr1768115201681152077mer-m86811518868115208141-10.48
ADediting_1548400chr17_68115202_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548ah-3pchr1768115201681152077mer-m86811518968115208145-11.33
ADediting_1548400chr17_68115202_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548aj-3pchr1768115201681152077mer-m86811518868115208141-8.37
ADediting_1548400chr17_68115202_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548am-3pchr1768115201681152077mer-m86811518968115208145-11.48
ADediting_1548400chr17_68115202_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548aq-3pchr1768115201681152077mer-m86811518768115208141-10.48
ADediting_1548400chr17_68115202_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548j-3pchr1768115201681152077mer-m86811518868115208146-10.48
ADediting_1548400chr17_68115202_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548x-3pchr1768115201681152077mer-m86811518968115208141-8.37
ADediting_1548400chr17_68115202_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-7844-5pchr1768115199681152057mer-m86811518568115206164-21.69
ADediting_1548401chr17_68115211_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-1283chr1768115205681152117mer-m86811518968115212155-14.27
ADediting_1548401chr17_68115211_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548ae-3pchr1768115210681152167mer-m86811519768115217157-9.37
ADediting_1548401chr17_68115211_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548ah-3pchr1768115210681152167mer-m86811519668115217153-10.97
ADediting_1548401chr17_68115211_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548aj-3pchr1768115210681152167mer-m86811519768115217157-10.27
ADediting_1548401chr17_68115211_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548am-3pchr1768115210681152167mer-m86811519668115217153-10.27
ADediting_1548401chr17_68115211_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548aq-3pchr1768115210681152167mer-m86811519668115217157-10.4
ADediting_1548401chr17_68115211_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548j-3pchr1768115210681152167mer-m86811519768115217157-9.77
ADediting_1548401chr17_68115211_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-548x-3pchr1768115210681152167mer-m86811519868115217157-10.27
ADediting_659070chr17_68115079_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-3940-3pchr1768115077681150837mer-m86811506368115084151-22.47
ADediting_659073chr17_68115116_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-17-3pchr1768115110681151167mer-m86811509668115117150-18.3
ADediting_659073chr17_68115116_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-485-5pchr1768115114681151207mer-m86811510168115121154-18.59
ADediting_659073chr17_68115116_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6884-5pchr1768115114681151207mer-m86811510368115121142-21.71
ADediting_659074chr17_68115135_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-516a-5pchr1768115132681151387mer-m86811511768115139141-19.6
ADediting_659075chr17_68115136_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-1199-5pchr1768115130681151367mer-m86811511868115137151-25.39
ADediting_659075chr17_68115136_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-1200chr1768115132681151387mer-m86811511768115139153-24.54
ADediting_659075chr17_68115136_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6751-3pchr1768115130681151367mer-m86811511768115137145-14.52
ADediting_659076chr17_68115138_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-188-5pchr1768115135681151417mer-m86811512268115142145-14.29
ADediting_659076chr17_68115138_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-4780chr1768115133681151408mer-1a6811511968115140157-22.55
ADediting_659076chr17_68115138_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-623chr1768115134681151407mer-m86811512068115141145-23.09
ADediting_659076chr17_68115138_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6866-3pchr1768115135681151417mer-m86811512168115142146-18.3
ADediting_659077chr17_68115148_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6765-5pchr1768115147681151537mer-m86811513368115154153-25.88
ADediting_659079chr17_68115162_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6840-3pchr1768115157681151637mer-m86811514368115164156-27.54
ADediting_659080chr17_68115165_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6743-3pchr1768115161681151677mer-m86811514668115168140-19.35
ADediting_659081chr17_68115175_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-17-3pchr1768115172681151787mer-m86811515868115179142-20.77
ADediting_659082chr17_68115177_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-100-5pchr1768115174681151818mer-1a6811516168115181160-23.04
ADediting_659082chr17_68115177_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-99a-5pchr1768115174681151818mer-1a6811516168115181160-23.04
ADediting_659082chr17_68115177_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-99b-5pchr1768115174681151818mer-1a6811516068115181152-23.64
ADediting_659083chr17_68115181_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-4327chr1768115180681151867mer-m86811516968115187141-17.25
ADediting_659083chr17_68115181_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-500a-3pchr1768115177681151848mer-1a6811516368115184145-18.96
ADediting_659083chr17_68115181_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6804-3pchr1768115176681151838mer-1a6811516168115183148-17.23
ADediting_659085chr17_68115184_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-486-5pchr1768115179681151857mer-m86811516568115186149-19.89
ADediting_659085chr17_68115184_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6735-3pchr1768115181681151888mer-1a6811516568115188149-24.89
ADediting_659086chr17_68115188_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6770-3pchr1768115185681151917mer-m86811517168115192158-22.54
ADediting_659087chr17_68115201_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-1207-3pchr1768115195681152028mer-1a6811518568115202145-17.57
ADediting_659087chr17_68115201_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-34a-3pchr1768115198681152047mer-m86811518368115205143-9.45
ADediting_659091chr17_68115247_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-4645-5pchr1768115242681152487mer-m86811523168115249147-14.37
ADediting_659091chr17_68115247_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-4673chr1768115242681152487mer-m86811522768115249152-21.99
ADediting_659091chr17_68115247_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-4690-3pchr1768115246681152538mer-1a6811523368115253149-19.12
ADediting_659091chr17_68115247_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-4742-5pchr1768115241681152477mer-m86811522468115248144-18.12
ADediting_659091chr17_68115247_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-5685chr1768115246681152538mer-1a6811523268115253153-21.61
ADediting_659092chr17_68115259_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-1289chr1768115258681152647mer-m86811524468115265158-21.8
ADediting_659093chr17_68115260_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-28-5pchr1768115259681152657mer-m86811524168115266155-21.67
ADediting_659093chr17_68115260_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-3139chr1768115259681152657mer-m86811524468115266161-24.89
ADediting_659093chr17_68115260_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-708-5pchr1768115259681152657mer-m86811524568115266154-17.79
ADediting_659096chr17_68115276_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-1255b-2-3pchr1768115272681152787mer-m86811526168115279142-14.7
ADediting_659097chr17_68115300_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-3189-3pchr1768115295681153017mer-m86811528368115302149-28.89
ADediting_659097chr17_68115300_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6813-3pchr1768115296681153027mer-m86811528368115303140-12.15

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_659070chr17_68115079_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-1262chr1768115073681150797mer-m86811452368115080144-16.95
ADediting_659070chr17_68115079_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-4701-3pchr1768115073681150797mer-m86811506168115080153-18.62
ADediting_659070chr17_68115079_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-661chr1768115076681150827mer-m86811452568115083147-20.51
ADediting_659070chr17_68115079_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6736-5pchr1768115073681150797mer-m86811452568115080143-20.97
ADediting_659070chr17_68115079_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6742-3pchr1768115075681150817mer-m86811506368115082140-13.49
ADediting_659073chr17_68115116_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-377-5pchr1768115114681151207mer-m86811510068115121145-17.7
ADediting_659073chr17_68115116_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6086chr1768115114681151207mer-m86811510268115121142-22.54
ADediting_659073chr17_68115116_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6516-5pchr1768115110681151167mer-m86811509668115117148-15.03
ADediting_659074chr17_68115135_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-526b-5pchr1768115132681151387mer-m86811511768115139146-17.62
ADediting_659075chr17_68115136_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-526b-5pchr1768115132681151387mer-m86811511768115139146-17.62
ADediting_659076chr17_68115138_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-526b-5pchr1768115132681151387mer-m86811511768115139146-17.62
ADediting_659077chr17_68115148_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-1233-5pchr1768115143681151497mer-m86811512568115150147-26.35
ADediting_659077chr17_68115148_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-1273h-5pchr1768115142681151487mer-m86811512868115149141-16.04
ADediting_659077chr17_68115148_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-30b-3pchr1768115142681151487mer-m86811513168115149141-13.71
ADediting_659077chr17_68115148_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-3689a-3pchr1768115142681151487mer-m86811513268115149143-14.62
ADediting_659077chr17_68115148_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-3689b-3pchr1768115142681151487mer-m86811513068115149144-15.36
ADediting_659077chr17_68115148_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-3689cchr1768115142681151487mer-m86811513068115149144-15.36
ADediting_659077chr17_68115148_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6778-5pchr1768115143681151497mer-m86811512968115150150-23.18
ADediting_659077chr17_68115148_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6779-5pchr1768115142681151487mer-m86811512968115149148-21.53
ADediting_659077chr17_68115148_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-6780a-5pchr1768115142681151487mer-m86811512768115149141-18.98
ADediting_659078chr17_68115153_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-4478chr1768115151681151577mer-m86811514268115158155-27.09
ADediting_659078chr17_68115153_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-485-5pchr1768115152681151587mer-m86811513768115159149-17.15
ADediting_659078chr17_68115153_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-7160-5pchr1768115149681151557mer-m86811513668115156150-18.56
ADediting_659078chr17_68115153_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-7162-3pchr1768115148681151547mer-m86811513768115155152-18.02
ADediting_659079chr17_68115162_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-3664-3pchr1768115157681151637mer-m86811514168115164147-16.66
ADediting_659079chr17_68115162_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-767-3pchr1768115160681151667mer-m86811514568115167140-12.87
ADediting_659080chr17_68115165_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-767-3pchr1768115160681151667mer-m86811514568115167140-12.87
ADediting_659081chr17_68115175_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-20b-3pchr1768115172681151787mer-m86811515868115179151-15.85
ADediting_659082chr17_68115177_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-20b-3pchr1768115172681151787mer-m86811515868115179151-15.85
ADediting_659089chr17_68115221_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-1283chr1768115216681152238mer-1a6811520268115223152-12.62
ADediting_659089chr17_68115221_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-3675-3pchr1768115220681152267mer-m86811520668115227149-12.58
ADediting_659089chr17_68115221_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-4684-5pchr1768115219681152257mer-m86811520268115226151-11.22
ADediting_659089chr17_68115221_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-519a-2-5pchr1768115218681152258mer-1a6811520568115225154-15.27
ADediting_659089chr17_68115221_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-520b-5pchr1768115218681152258mer-1a6811520568115225154-15.27
ADediting_659091chr17_68115247_+ENSG00000237854.3ENST00000435469.2LINC00674-201hsa-miR-3135achr1768115244681152507mer-m86811523168115251148-17.57

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for LINC00674

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000435469.2lncRNASoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_659070ENST00000435469.2chr17_68115079_+239-188.80-188.20-220.70
ADediting_659071ENST00000435469.2chr17_68115091_+251-186.90-188.20-220.70
ADediting_659072ENST00000435469.2chr17_68115100_+260-188.20-188.20-220.70
ADediting_659073ENST00000435469.2chr17_68115116_+276-188.20-188.20-220.70
ADediting_659074ENST00000435469.2chr17_68115135_+295-188.50-188.20-220.70
ADediting_659075ENST00000435469.2chr17_68115136_+296-194.40-188.20-220.70
ADediting_659076ENST00000435469.2chr17_68115138_+298-188.80-188.20-220.70
ADediting_659077ENST00000435469.2chr17_68115148_+308-189.00-188.20-220.70
ADediting_659078ENST00000435469.2chr17_68115153_+313-188.20-188.20-220.70
ADediting_659079ENST00000435469.2chr17_68115162_+322-190.00-188.20-220.70
ADediting_659080ENST00000435469.2chr17_68115165_+325-188.10-188.20-220.70
ADediting_659081ENST00000435469.2chr17_68115175_+335-189.40-188.20-220.70
ADediting_659082ENST00000435469.2chr17_68115177_+337-189.00-188.20-220.70
ADediting_659083ENST00000435469.2chr17_68115181_+341-190.00-188.20-220.70
ADediting_659084ENST00000435469.2chr17_68115183_+343-188.20-188.20-220.70
ADediting_659085ENST00000435469.2chr17_68115184_+344-188.30-188.20-220.70
ADediting_659086ENST00000435469.2chr17_68115188_+348-189.20-188.20-220.70
ADediting_659087ENST00000435469.2chr17_68115201_+361-191.00-188.20-220.70
ADediting_1548400ENST00000435469.2chr17_68115202_+362-187.90-188.20-220.70
ADediting_659088ENST00000435469.2chr17_68115210_+370-187.30-188.20-220.70
ADediting_1548401ENST00000435469.2chr17_68115211_+371-188.40-188.20-220.70
ADediting_659089ENST00000435469.2chr17_68115221_+381-190.30-188.20-220.70
ADediting_659090ENST00000435469.2chr17_68115238_+398-188.90-188.20-220.70
ADediting_659091ENST00000435469.2chr17_68115247_+407-190.30-188.20-220.70
ADediting_659092ENST00000435469.2chr17_68115259_+419-191.00-188.20-220.70
ADediting_659093ENST00000435469.2chr17_68115260_+420-190.80-188.20-220.70
ADediting_659094ENST00000435469.2chr17_68115272_+432-189.80-188.20-220.70
ADediting_659095ENST00000435469.2chr17_68115273_+433-190.20-188.20-220.70
ADediting_659096ENST00000435469.2chr17_68115276_+436-187.90-188.20-220.70
ADediting_659097ENST00000435469.2chr17_68115300_+460-188.50-188.20-220.70
ADediting_659098ENST00000435469.2chr17_68115312_+472-188.50-188.20-220.70

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Relation with ADAR for LINC00674

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_659070chr17_68115079_+0.00403468853563350.2334777955251820.0001127368239409760.3100696471221080.5492319167903710.049283467013782
CERADediting_659071chr17_68115091_+0.01358170748979560.2011414129377999.31649287607011e-050.3136018114859720.04462829734214090.164222897081426
CERADediting_659077chr17_68115148_+0.0005573859562752580.2785489051548332.48664365527233e-050.3369340297212050.6146126621624640.0414396115832291
CERADediting_659080chr17_68115165_+0.003523259985747680.2368327857857041.13511970399971e-050.3499448419134740.6365220294505670.0388957194099032
CERADediting_659081chr17_68115175_+0.0001834294908285630.3008454905391352.98577433894601e-060.3708605496393050.06795819361754720.149445906206701
DLPFCADediting_659089chr17_68115221_+0.1668677480417010.078707672827620.801775417035777-0.01431578602017673.71654627732108e-100.34619062697103
CERADediting_659096chr17_68115276_+0.005582954041722350.2252462207251930.0001170114462146860.3093750742237880.1316397766567390.123661983573044

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC8.55636053455893e-050.2212330035653280.963063117239045-0.002640898960563497.20714669707211e-750.814689537919848
AC5.27111509058447e-230.570703839764471.07766204139818e-150.4782580942460532.42023582014847e-200.540222423554799
CER1.62805161819214e-140.5739004051473767.35213910548149e-170.6132047868292892.49032627778937e-060.373592366685891
TCX0.0003778261857300060.2865586214562710.0452585886320504-0.1637471062461291.95931892132832e-150.589953229684222
FP4.44735726136462e-070.367669915943640.03624207966215590.1570977968526133.74437472548254e-120.490282093121517
IFG0.0050176530144980.5431679650035930.00122487059076270.6093131830521240.030735868629980.432713618586704
PG1.16245620737312e-130.5091671021603395.87996985665234e-060.3253158996603940.1122422347199640.116840554519503
STG0.009145718232528870.2828053756758650.6554576295733160.04939405812722370.003550973855667380.314699950785921

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Relation with AD stages for LINC00674

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER7.65086500436005e-050.371206524486085
TCX1.01670846894104e-050.41418103233555

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RelatedDrugs for LINC00674

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for LINC00674

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource