|
||||||
|
 | |
| |
| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
| |
| |
| The effects of the RNA editing to the stability of the RNA structures |
| |
| |
| |
|
Gene summary for GLOD4 |
 Gene summary |
| Gene information | Gene symbol | GLOD4 | Gene ID | 51031 |
| Gene name | glyoxalase domain containing 4 | |
| Synonyms | C17orf25|CGI-150|HC71 | |
| Cytomap | 17p13.3 | |
| Type of gene | protein-coding | |
| Description | glyoxalase domain-containing protein 4 | |
| Modification date | 20200313 | |
| UniProtAcc | Q9HC38, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for GLOD4 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_663855(757550, -), ADediting_663856(757584, -), ADediting_663857(757595, -), ADediting_663860(757603, -), ADediting_663865(757643, -), ADediting_663866(757666, -), ADediting_663867(757672, -), ADediting_663868(757675, -), ADediting_664231(758040, -), ADediting_664296(758062, -), ADediting_664380(758116, -), ADediting_664488(758836, -), ADediting_665305(761669, -), ADediting_665321(761707, -), ADediting_665322(761708, -), ADediting_665359(761755, -), ADediting_666002(763490, -), ADediting_669023(779070, -), ADediting_669024(779085, -), ADediting_669025(779094, -), ADediting_669026(779152, -), ADediting_669027(779185, -), ADediting_669028(779190, -), ADediting_669029(779193, -), ADediting_669030(779214, -), ADediting_669031(779232, -), ADediting_669032(779270, -), ADediting_669033(779306, -), ADediting_669035(779513, -), ADediting_669036(779516, -), ADediting_669037(779543, -), ADediting_669039(779592, -), ADediting_669235(779908, -), ADediting_669236(779920, -), ADediting_669244(779975, -), ADediting_669245(779997, -), ADediting_669246(780042, -), ADediting_669247(780052, -), ADediting_669251(780117, -), ADediting_669252(780118, -), ADediting_669325(780551, -), ADediting_669327(780573, -), ADediting_669328(780576, -), ADediting_669333(780611, -), ADediting_669334(780621, -), ADediting_669338(780631, -), ADediting_669363(780696, -), ADediting_669388(780926, -), ADediting_669394(780948, -), ADediting_669409(780981, -), ADediting_669410(780993, -), ADediting_669411(781031, -), ADediting_669412(781049, -), ADediting_669413(781058, -), ADediting_669414(781059, -), ADediting_669415(781085, -), ADediting_669421(781094, -), ADediting_669429(781100, -), ADediting_669435(781114, -), ADediting_669436(781124, -), ADediting_669437(781125, -), ADediting_669438(781148, -), ADediting_669439(781158, -), ADediting_669457(781171, -), ADediting_669458(781193, -), ADediting_669459(781194, -), ADediting_1549214(758053, -), ADediting_1549215(758054, -), ADediting_1549493(779158, -), ADediting_1549494(779187, -), ADediting_1549497(779921, -), ADediting_1628738(757546, -), ADediting_1628765(761711, -), ADediting_1628814(780986, -), |
Top |
RNA editing positional annotations for GLOD4 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_669363 | chr17_780696_- | nonsynonymous SNV | ENST00000301328.9 | c.A133G | p.I45V | 0.087 | 0.0 | 0.08 |
| ADediting_669363 | chr17_780696_- | nonsynonymous SNV | ENST00000574581.5 | c.A133G | p.I45V | 0.087 | 0.0 | 0.08 |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_663855 | chr17_757550_- | intergenic |
| ADediting_663856 | chr17_757584_- | intergenic |
| ADediting_663857 | chr17_757595_- | intergenic |
| ADediting_663860 | chr17_757603_- | intergenic |
| ADediting_663865 | chr17_757643_- | intergenic |
| ADediting_663866 | chr17_757666_- | intergenic |
| ADediting_663867 | chr17_757672_- | intergenic |
| ADediting_663868 | chr17_757675_- | intergenic |
| ADediting_664231 | chr17_758040_- | intergenic |
| ADediting_664296 | chr17_758062_- | intergenic |
| ADediting_664380 | chr17_758116_- | downstream |
| ADediting_664488 | chr17_758836_- | downstream |
| ADediting_665305 | chr17_761669_- | intronic |
| ADediting_665321 | chr17_761707_- | intronic |
| ADediting_665322 | chr17_761708_- | intronic |
| ADediting_665359 | chr17_761755_- | intronic |
| ADediting_666002 | chr17_763490_- | intronic |
| ADediting_669023 | chr17_779070_- | intronic |
| ADediting_669024 | chr17_779085_- | intronic |
| ADediting_669025 | chr17_779094_- | intronic |
| ADediting_669026 | chr17_779152_- | intronic |
| ADediting_669027 | chr17_779185_- | intronic |
| ADediting_669028 | chr17_779190_- | intronic |
| ADediting_669029 | chr17_779193_- | intronic |
| ADediting_669030 | chr17_779214_- | intronic |
| ADediting_669031 | chr17_779232_- | intronic |
| ADediting_669032 | chr17_779270_- | intronic |
| ADediting_669033 | chr17_779306_- | intronic |
| ADediting_669035 | chr17_779513_- | intronic |
| ADediting_669036 | chr17_779516_- | intronic |
| ADediting_669037 | chr17_779543_- | intronic |
| ADediting_669039 | chr17_779592_- | intronic |
| ADediting_669235 | chr17_779908_- | intronic |
| ADediting_669236 | chr17_779920_- | intronic |
| ADediting_669244 | chr17_779975_- | intronic |
| ADediting_669245 | chr17_779997_- | intronic |
| ADediting_669246 | chr17_780042_- | intronic |
| ADediting_669247 | chr17_780052_- | intronic |
| ADediting_669251 | chr17_780117_- | intronic |
| ADediting_669252 | chr17_780118_- | intronic |
| ADediting_669325 | chr17_780551_- | intronic |
| ADediting_669327 | chr17_780573_- | intronic |
| ADediting_669328 | chr17_780576_- | intronic |
| ADediting_669333 | chr17_780611_- | intronic |
| ADediting_669334 | chr17_780621_- | intronic |
| ADediting_669338 | chr17_780631_- | intronic |
| ADediting_669363 | chr17_780696_- | exonic |
| ADediting_669388 | chr17_780926_- | intronic |
| ADediting_669394 | chr17_780948_- | intronic |
| ADediting_669409 | chr17_780981_- | intronic |
| ADediting_669410 | chr17_780993_- | intronic |
| ADediting_669411 | chr17_781031_- | intronic |
| ADediting_669412 | chr17_781049_- | intronic |
| ADediting_669413 | chr17_781058_- | intronic |
| ADediting_669414 | chr17_781059_- | intronic |
| ADediting_669415 | chr17_781085_- | intronic |
| ADediting_669421 | chr17_781094_- | intronic |
| ADediting_669429 | chr17_781100_- | intronic |
| ADediting_669435 | chr17_781114_- | intronic |
| ADediting_669436 | chr17_781124_- | intronic |
| ADediting_669437 | chr17_781125_- | intronic |
| ADediting_669438 | chr17_781148_- | intronic |
| ADediting_669439 | chr17_781158_- | intronic |
| ADediting_669457 | chr17_781171_- | intronic |
| ADediting_669458 | chr17_781193_- | intronic |
| ADediting_669459 | chr17_781194_- | intronic |
| ADediting_1549214 | chr17_758053_- | intergenic |
| ADediting_1549215 | chr17_758054_- | intergenic |
| ADediting_1549493 | chr17_779158_- | intronic |
| ADediting_1549494 | chr17_779187_- | intronic |
| ADediting_1549497 | chr17_779921_- | intronic |
| ADediting_1628738 | chr17_757546_- | intergenic |
| ADediting_1628765 | chr17_761711_- | intronic |
| ADediting_1628814 | chr17_780986_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_663855 | chr17_757550_- | SINE | Alu | Name=AluSp |
| ADediting_663856 | chr17_757584_- | SINE | Alu | Name=AluSp |
| ADediting_663857 | chr17_757595_- | SINE | Alu | Name=AluSp |
| ADediting_663860 | chr17_757603_- | SINE | Alu | Name=AluSp |
| ADediting_663865 | chr17_757643_- | SINE | Alu | Name=AluSp |
| ADediting_663866 | chr17_757666_- | SINE | Alu | Name=AluSp |
| ADediting_663867 | chr17_757672_- | SINE | Alu | Name=AluSp |
| ADediting_663868 | chr17_757675_- | SINE | Alu | Name=AluSp |
| ADediting_664231 | chr17_758040_- | SINE | Alu | Name=AluSp |
| ADediting_664296 | chr17_758062_- | SINE | Alu | Name=AluSp |
| ADediting_664380 | chr17_758116_- | SINE | Alu | Name=AluSp |
| ADediting_664488 | chr17_758836_- | SINE | Alu | Name=AluSp |
| ADediting_665305 | chr17_761669_- | SINE | Alu | Name=AluSq2 |
| ADediting_665321 | chr17_761707_- | SINE | Alu | Name=AluSq2 |
| ADediting_665322 | chr17_761708_- | SINE | Alu | Name=AluSq2 |
| ADediting_665359 | chr17_761755_- | SINE | Alu | Name=AluSq2 |
| ADediting_666002 | chr17_763490_- | SINE | Alu | Name=AluSx1 |
| ADediting_669023 | chr17_779070_- | SINE | Alu | Name=AluSq2 |
| ADediting_669024 | chr17_779085_- | SINE | Alu | Name=AluSq2 |
| ADediting_669025 | chr17_779094_- | SINE | Alu | Name=AluSq2 |
| ADediting_669026 | chr17_779152_- | SINE | Alu | Name=AluSq2 |
| ADediting_669027 | chr17_779185_- | SINE | Alu | Name=AluSq2 |
| ADediting_669028 | chr17_779190_- | SINE | Alu | Name=AluSq2 |
| ADediting_669029 | chr17_779193_- | SINE | Alu | Name=AluSq2 |
| ADediting_669030 | chr17_779214_- | SINE | Alu | Name=AluSq2 |
| ADediting_669031 | chr17_779232_- | SINE | Alu | Name=AluSq2 |
| ADediting_669032 | chr17_779270_- | SINE | Alu | Name=AluSq2 |
| ADediting_669033 | chr17_779306_- | SINE | Alu | Name=AluSq2 |
| ADediting_669035 | chr17_779513_- | SINE | Alu | Name=AluSq2 |
| ADediting_669036 | chr17_779516_- | SINE | Alu | Name=AluSq2 |
| ADediting_669037 | chr17_779543_- | SINE | Alu | Name=AluSq2 |
| ADediting_669039 | chr17_779592_- | SINE | Alu | Name=AluSq2 |
| ADediting_669235 | chr17_779908_- | SINE | Alu | Name=AluY |
| ADediting_669236 | chr17_779920_- | SINE | Alu | Name=AluY |
| ADediting_669244 | chr17_779975_- | SINE | Alu | Name=AluY |
| ADediting_669245 | chr17_779997_- | SINE | Alu | Name=AluY |
| ADediting_669246 | chr17_780042_- | SINE | Alu | Name=AluY |
| ADediting_669247 | chr17_780052_- | SINE | Alu | Name=AluY |
| ADediting_669251 | chr17_780117_- | SINE | Alu | Name=AluY |
| ADediting_669252 | chr17_780118_- | SINE | Alu | Name=AluY |
| ADediting_669325 | chr17_780551_- | SINE | Alu | Name=AluY |
| ADediting_669327 | chr17_780573_- | SINE | Alu | Name=AluY |
| ADediting_669328 | chr17_780576_- | SINE | Alu | Name=AluY |
| ADediting_669333 | chr17_780611_- | SINE | Alu | Name=AluY |
| ADediting_669334 | chr17_780621_- | SINE | Alu | Name=AluY |
| ADediting_669338 | chr17_780631_- | SINE | Alu | Name=AluY |
| ADediting_669363 | chr17_780696_- | SINE | Alu | Name=AluY |
| ADediting_669388 | chr17_780926_- | SINE | Alu | Name=AluSq2 |
| ADediting_669394 | chr17_780948_- | SINE | Alu | Name=AluSq2 |
| ADediting_669409 | chr17_780981_- | SINE | Alu | Name=AluSq2 |
| ADediting_669410 | chr17_780993_- | SINE | Alu | Name=AluSq2 |
| ADediting_669411 | chr17_781031_- | SINE | Alu | Name=AluSq2 |
| ADediting_669412 | chr17_781049_- | SINE | Alu | Name=AluSq2 |
| ADediting_669413 | chr17_781058_- | SINE | Alu | Name=AluSq2 |
| ADediting_669414 | chr17_781059_- | SINE | Alu | Name=AluSq2 |
| ADediting_669415 | chr17_781085_- | SINE | Alu | Name=AluSq2 |
| ADediting_669421 | chr17_781094_- | SINE | Alu | Name=AluSq2 |
| ADediting_669429 | chr17_781100_- | SINE | Alu | Name=AluSq2 |
| ADediting_669435 | chr17_781114_- | SINE | Alu | Name=AluSq2 |
| ADediting_669436 | chr17_781124_- | SINE | Alu | Name=AluSq2 |
| ADediting_669437 | chr17_781125_- | SINE | Alu | Name=AluSq2 |
| ADediting_669438 | chr17_781148_- | SINE | Alu | Name=AluSq2 |
| ADediting_669439 | chr17_781158_- | SINE | Alu | Name=AluSq2 |
| ADediting_669457 | chr17_781171_- | SINE | Alu | Name=AluSq2 |
| ADediting_669458 | chr17_781193_- | SINE | Alu | Name=AluSq2 |
| ADediting_669459 | chr17_781194_- | SINE | Alu | Name=AluSq2 |
| ADediting_1549214 | chr17_758053_- | SINE | Alu | Name=AluSp |
| ADediting_1549215 | chr17_758054_- | SINE | Alu | Name=AluSp |
| ADediting_1549493 | chr17_779158_- | SINE | Alu | Name=AluSq2 |
| ADediting_1549494 | chr17_779187_- | SINE | Alu | Name=AluSq2 |
| ADediting_1549497 | chr17_779921_- | SINE | Alu | Name=AluY |
| ADediting_1628738 | chr17_757546_- | SINE | Alu | Name=AluSp |
| ADediting_1628765 | chr17_761711_- | SINE | Alu | Name=AluSq2 |
| ADediting_1628814 | chr17_780986_- | SINE | Alu | Name=AluSq2 |
Top |
RNA A-to-I editing events in the alternative splicing sites for GLOD4 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for GLOD4 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |