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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for NPIPB15 |
 Gene summary |
| Gene information | Gene symbol | NPIPB15 | Gene ID | 440348 |
| Gene name | nuclear pore complex interacting protein family member B15 | |
| Synonyms | A-761H5.4|NPIPL2 | |
| Cytomap | 16q23.1 | |
| Type of gene | protein-coding | |
| Description | nuclear pore complex-interacting protein family member B15nuclear pore complex interacting protein-like 2 | |
| Modification date | 20200313 | |
| UniProtAcc | A6NHN6, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for NPIPB15 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_570197(74379074, +), ADediting_570198(74379690, +), ADediting_570199(74379850, +), ADediting_570200(74379880, +), ADediting_570201(74391950, +), ADediting_1544142(74378137, +), ADediting_1625323(74381095, +), |
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RNA editing positional annotations for NPIPB15 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_570201 | chr16_74391950_+ | nonsynonymous SNV | ENST00000429990.1 | c.A1202G | p.K401R | 0.0 | 0.064 | -1.32 |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_570197 | chr16_74379074_+ | intronic |
| ADediting_570198 | chr16_74379690_+ | intronic |
| ADediting_570199 | chr16_74379850_+ | intronic |
| ADediting_570200 | chr16_74379880_+ | intronic |
| ADediting_570201 | chr16_74391950_+ | exonic |
| ADediting_1544142 | chr16_74378137_+ | intronic |
| ADediting_1625323 | chr16_74381095_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_570197 | chr16_74379074_+ | SINE | Alu | Name=AluSp |
| ADediting_570198 | chr16_74379690_+ | SINE | Alu | Name=AluSc8 |
| ADediting_570199 | chr16_74379850_+ | SINE | Alu | Name=AluSc8 |
| ADediting_570200 | chr16_74379880_+ | SINE | Alu | Name=AluSc8 |
| ADediting_570201 | chr16_74391950_+ | SINE | Alu | Name=AluSp |
| ADediting_1544142 | chr16_74378137_+ | SINE | Alu | Name=AluJb |
| ADediting_1625323 | chr16_74381095_+ | SINE | Alu | Name=AluSx1 |
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RNA A-to-I editing events in the alternative splicing sites for NPIPB15 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NPIPB15 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |